Infectious Dose

In this Outbreak After Dark episode, we revisit Thanksgiving’s origin story through the lens of infectious disease. Heather, Sam, and Kate dive into the epidemics that devastated Indigenous nations before the Pilgrims ever arrived, the microbial mismatches between Old World and New, and the narratives that still distort how we talk about “the First Thanksgiving.” It’s a campfire conversation that blends history, science, myth-busti...

This week’s episode dives into the roots of the global antimicrobial resistance crisis. How did routine cuts, UTIs, and pneumonias become untreatable? What systems helped superbugs evolve — and why is the problem accelerating worldwide?

We explore the science, the policies, the failures, and the future of drug-resistant microbes in A Prescription for Pest...

Rift Valley fever is back — and it’s hitting harder than it has in years. In this episode, we trace the 2025 outbreak from Mauritania to Senegal, explore how the virus hides between rainy seasons, and reveal what scientists have learned from unexpected hotspots in Tanzania. From mosquitoes and livestock to people and policy, this is Rift Valley fever: when the rains bring life and loss.

Headed into holiday travel season? This episode of Infectious Dose is your go-to guide for staying healthy on the road — without panic, shame, or disinfecting your entire row like you're filming a CSI episode. We talk practical prevention for planes, airports, road trips, and cruises, including how to avoid RSV, norovirus, and long COVID, what to pack in your health kit, why snacks matter, and how to travel with kids without losing...

Welcome to Outbreak After Dark, a new monthly ritual within Infectious Dose, where the science stays real but the stories get darker, weirder, and yes—sometimes just plain gross.

In this Halloween premiere, Ocularium, Heather is joined by cohosts Kate and Sam, to share true “medical horror” stories about parasites that call the eye home: Loa loa, Onchocerca volvulus, Acanthamoeba, and Thelazia gulosa.

🍂 Grab your themed snacks an...

What if you couldn’t wake up—and your mind kept trying to lecture its way out of the dark?

In this week’s Month of the Macabre episode, “The Sleep Lecture,” a neurologist begins a talk on encephalitis lethargica—the mysterious “sleepy sickness” that swept the world a century ago—only to discover she’s become part of her own subject. Based on true clinical rec...

In this special Month of the Macabre episode, Infectious Dose steps into gothic territory with a haunting reimagining of Edgar Allan Poe’s The Raven—rewritten for the age of science denial.

The R@VN follows a man who built his fame on rejecting vaccines and mistrusting public health—until a disease he dismissed returns to claim him. As paralysis sets in...

In 1692, the people of Salem believed the Devil walked among them.

But centuries later, scientists and historians would wonder: could the culprit have been something far more earthly—a hallucinogenic fungus lurking in their daily bread?

This Month of the Macabre episode of Infectious Dose examines the ergotism theory...

Step into the shoes of a 1970s CDC outbreak detective as a mysterious cluster of fatal pneumonia cases pulls you into the shadows of a crumbling city hotel. In this immersive Month of the Macabre episode, you’ll chase clues through fog-filled ballrooms and forgotten ventilation shafts, racing to stop an invisible killer before it spreads. Along the way, the case, inspired by a real investigation, reveals just how crucial—and fragil...

Our public health safety net is unraveling. In this episode, we explore why infectious disease surveillance — once our invisible safety net — is quietly vanishing, and what that means for early outbreak detection. Dr. Jim Alwine breaks down common misunderstandings around gain-of-function research and explains how fear-driven narratives like the lab leak theory have warped public perception and policymaking. We also examine how rec...

Organizer–sociologist Jon Shaffer, PhD, (Defend Public Health / University of Vermont) joins Heather to talk about turning evidence into local, winnable public-health protections. We dig into why “apolitical” public health backfires, how real teams (not one-off mobilizations) build durable power, and practical, nonpartisan roles for scientists and clinicians—even if you only have an hour a month. Though this moment really deserves ...

West Nile virus is back in the headlines, with new human cases in the U.S. and steady activity in Europe. In this episode of Infectious Dose, Heather tracks the current outbreak season through CDC and ECDC surveillance and state-level reports, explores how the virus cycles between birds and mosquitoes, and examines what happens when you get infected. Most infections are silent, but for a small fraction, West Nile unleashes a devast...

Heather brings you a bonus mini Booster Dose episode to explain everything you need to know about the new changes in FDA-approved access to fall COVID shots, who’s eligible by brand/age, what counts as “underlying,” off-label/insurance realities, why ACIP mainly affects coverage (not labels), a brief CDC leadership update, and practical protections—documentation, ventilation, high-filtration ...

Back-to-school season means new teachers, new friends…and a whole new round of germs. From runny noses to strep throats, pinkeye to flu, classrooms are a breeding ground for illness once the school bell rings. In this episode of Infectious Dose, Heather breaks down the most common fall outbreaks in kids, when to keep children home, and the prevention strategies that actually make a difference.

In this gripping episode, we dive into the world of Vibrio vulnificus—a flesh-eating bacterium once confined to warm southern waters, now making deadly appearances from Florida to Cape Cod.

We begin with real-life cases from the 2025 surge across the U.S., then uncover the science behind this microscopic killer: how it invades, how it spreads, and why it’...

Chikungunya is sweeping through southern China in its largest recorded outbreak—and it’s not just a local problem. In this episode of Infectious Dose, Heather takes you inside Foshan’s summer surge, unpacks how this mosquito-borne virus travels the globe, and explores why its painful symptoms can linger for months or even years. You’ll hear how two species of mosquitoes are redrawing the map o...

What do vaccines really contain? Why do people still believe they cause autism? And who keeps spreading these lies?

In honor of Immunization Awareness Month, this special episode of Infectious Dose is your guided tour through our vaccine safety series. Heather maps out the key episodes that break down myths, expose disinformation campaigns, and explain ...

In this episode, Heather unpacks one of 2025’s most urgent and underreported global health crises.

Cholera—an ancient disease we know how to prevent and treat—is resurging across dozens of countries. But this isn’t about biology alone. From Sudan’s displaced families to Angola’s overcrowded clinics and the gold fields of the DRC, people are dying not from mystery—but from neglect.

You’ll learn what cholera is, how it spreads, how c...