Infectious dose is the shot of science you need to protect yourself from misinformation. Heather McSharry, PhD, an expert in viral pathogenesis, brings her blog to the airwaves to help bridge the dangerous gap between the science of infectious diseases and public misperception. On the podcast website, infectiousdose.com, all episodes have corresponding blog posts with the information contained in the episode along with links or PDFs for all sources used. To prevent unwelcome surprises, episodes with limited, mild profanity are marked as explicit. *Podcast intro and outro music are adapted from Heather Nova’s song, I Miss My Sky. Used with permission.
Show Notes — ACIP Undone: Proof, Policy, and Panic Over a Hepatitis B Vaccine
This episode unpacks everything you need to know about hepatitis B and the life-saving vaccine that helps prevent chronic liver disease and liver cancer later in life. From the biology of the virus to the science behind the birth dose, we explore how this vaccine works, why it’s given so early, and what’s at stake now that ideology is overriding evidence ...
A leaked FDA memo sparked headlines claiming the COVID vaccine killed children — but the memo included no evidence, no data, and no scientific analysis. In today’s episode, Heather unpacks what the memo actually said, why experts across the field immediately rejected its conclusions, and how vaccine safety is truly evaluated. She explains the real risks of COVID in kids, from MIS-C to long COVID, and why misinformation from inside ...
There’s more to your favorite winter rituals than nostalgia.
In this episode, we dive into how centuries of winter traditions—across Europe, Asia, Africa, and the Americas—offered accidental protection against infectious diseases. From citrus in stockings to cloves in mulled wine, from kimchi to candlelight, we trace how ancient practices around food, air...
In this Outbreak After Dark episode, we revisit Thanksgiving’s origin story through the lens of infectious disease. Heather, Sam, and Kate dive into the epidemics that devastated Indigenous nations before the Pilgrims ever arrived, the microbial mismatches between Old World and New, and the narratives that still distort how we talk about “the First Thanksgiving.” It’s a campfire conversation that blends history, science, myth-busti...
This week’s episode dives into the roots of the global antimicrobial resistance crisis. How did routine cuts, UTIs, and pneumonias become untreatable? What systems helped superbugs evolve — and why is the problem accelerating worldwide?
We explore the science, the policies, the failures, and the future of drug-resistant microbes in A Prescription for Pest...
Rift Valley fever is back — and it’s hitting harder than it has in years. In this episode, we trace the 2025 outbreak from Mauritania to Senegal, explore how the virus hides between rainy seasons, and reveal what scientists have learned from unexpected hotspots in Tanzania. From mosquitoes and livestock to people and policy, this is Rift Valley fever: when the rains bring life and loss.
Headed into holiday travel season? This episode of Infectious Dose is your go-to guide for staying healthy on the road — without panic, shame, or disinfecting your entire row like you're filming a CSI episode. We talk practical prevention for planes, airports, road trips, and cruises, including how to avoid RSV, norovirus, and long COVID, what to pack in your health kit, why snacks matter, and how to travel with kids without losing...
Welcome to Outbreak After Dark, a new monthly ritual within Infectious Dose, where the science stays real but the stories get darker, weirder, and yes—sometimes just plain gross.
In this Halloween premiere, Ocularium, Heather is joined by cohosts Kate and Sam, to share true “medical horror” stories about parasites that call the eye home: Loa loa, Onchocerca volvulus, Acanthamoeba, and Thelazia gulosa.
🍂 Grab your themed snacks an...
What if you couldn’t wake up—and your mind kept trying to lecture its way out of the dark?
In this week’s Month of the Macabre episode, “The Sleep Lecture,” a neurologist begins a talk on encephalitis lethargica—the mysterious “sleepy sickness” that swept the world a century ago—only to discover she’s become part of her own subject. Based on true clinical rec...
In this special Month of the Macabre episode, Infectious Dose steps into gothic territory with a haunting reimagining of Edgar Allan Poe’s The Raven—rewritten for the age of science denial.
The R@VN follows a man who built his fame on rejecting vaccines and mistrusting public health—until a disease he dismissed returns to claim him. As paralysis sets in...
In 1692, the people of Salem believed the Devil walked among them.
But centuries later, scientists and historians would wonder: could the culprit have been something far more earthly—a hallucinogenic fungus lurking in their daily bread?
This Month of the Macabre episode of Infectious Dose examines the ergotism theory...
Step into the shoes of a 1970s CDC outbreak detective as a mysterious cluster of fatal pneumonia cases pulls you into the shadows of a crumbling city hotel. In this immersive Month of the Macabre episode, you’ll chase clues through fog-filled ballrooms and forgotten ventilation shafts, racing to stop an invisible killer before it spreads. Along the way, the case, inspired by a real investigation, reveals just how crucial—and fragil...
Our public health safety net is unraveling. In this episode, we explore why infectious disease surveillance — once our invisible safety net — is quietly vanishing, and what that means for early outbreak detection. Dr. Jim Alwine breaks down common misunderstandings around gain-of-function research and explains how fear-driven narratives like the lab leak theory have warped public perception and policymaking. We also examine how rec...
Organizer–sociologist Jon Shaffer, PhD, (Defend Public Health / University of Vermont) joins Heather to talk about turning evidence into local, winnable public-health protections. We dig into why “apolitical” public health backfires, how real teams (not one-off mobilizations) build durable power, and practical, nonpartisan roles for scientists and clinicians—even if you only have an hour a month. Though this moment really deserves ...
West Nile virus is back in the headlines, with new human cases in the U.S. and steady activity in Europe. In this episode of Infectious Dose, Heather tracks the current outbreak season through CDC and ECDC surveillance and state-level reports, explores how the virus cycles between birds and mosquitoes, and examines what happens when you get infected. Most infections are silent, but for a small fraction, West Nile unleashes a devast...
This week, Heather pulls back the curtain on how she figures out what’s true. From gut checks and trusted sources to the brutal training of grad school and the constant practice of science writing, she shares the habits that help her navigate conflicting claims—like the current confusion around COVID vaccine access. You don’t need a PhD to think like a scientist, just the right process.
Heather brings you a bonus mini Booster Dose episode to explain everything you need to know about the new changes in FDA-approved access to fall COVID shots, who’s eligible by brand/age, what counts as “underlying,” off-label/insurance realities, why ACIP mainly affects coverage (not labels), a brief CDC leadership update, and practical protections—documentation, ventilation, high-filtration ...
Back-to-school season means new teachers, new friends…and a whole new round of germs. From runny noses to strep throats, pinkeye to flu, classrooms are a breeding ground for illness once the school bell rings. In this episode of Infectious Dose, Heather breaks down the most common fall outbreaks in kids, when to keep children home, and the prevention strategies that actually make a difference.
<...In this gripping episode, we dive into the world of Vibrio vulnificus—a flesh-eating bacterium once confined to warm southern waters, now making deadly appearances from Florida to Cape Cod.
We begin with real-life cases from the 2025 surge across the U.S., then uncover the science behind this microscopic killer: how it invades, how it spreads, and why it’...
Chikungunya is sweeping through southern China in its largest recorded outbreak—and it’s not just a local problem. In this episode of Infectious Dose, Heather takes you inside Foshan’s summer surge, unpacks how this mosquito-borne virus travels the globe, and explores why its painful symptoms can linger for months or even years. You’ll hear how two species of mosquitoes are redrawing the map o...
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
Listen to 'The Bobby Bones Show' by downloading the daily full replay.
The official podcast of comedian Joe Rogan.
Betrayal Weekly is back for a brand new season. Every Thursday, Betrayal Weekly shares first-hand accounts of broken trust, shocking deceptions, and the trail of destruction they leave behind. Hosted by Andrea Gunning, this weekly ongoing series digs into real-life stories of betrayal and the aftermath. From stories of double lives to dark discoveries, these are cautionary tales and accounts of resilience against all odds. From the producers of the critically acclaimed Betrayal series, Betrayal Weekly drops new episodes every Thursday. Please join our Substack for additional exclusive content, curated book recommendations and community discussions. Sign up FREE by clicking this link Beyond Betrayal Substack. Join our community dedicated to truth, resilience and healing. Your voice matters! Be a part of our Betrayal journey on Substack. And make sure to check out Seasons 1-4 of Betrayal, along with Betrayal Weekly Season 1.