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July 14, 2025 66 mins

When Mark Lacey was diagnosed with metastatic prostate cancer, his PSA was 3,500 and his scan was lit up from head to toe. Less than a year later, most of the bone mets are gone. In this honest, hard-hitting conversation, Mark shares what worked and why he’s still here — still farming, still thinking, still fighting.

  • Orchiectomy causes a flatline in testosterone, but doesn’t interfere with the brain’s signaling loop.

  • This stabilizes hormonal levels — no peaks, valleys, or drug half-lives to manage.

  • In some men, this steady state reduces cognitive side effects that were present on drug-based ADT.

Orchiectomy eliminates fluctuations

Mark as Played

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