SetSet with April Pride

SetSet with April Pride

SetSet supports women exploring psychedelics. This show is intended for anyone seeking transformation with the assistance of psychoactive substances. If you're looking to "trip" with friends or "journey" with a trained facilitator, SetSet offers practical, seasoned insights to help you optimize the potential of your next experience. Host April Pride shares expert knowledge, anecdotal stories, and data-backed resources for listeners, including as they integrate their insights and discoveries from expanded consciousness. aprilpride.substack.com

Episodes

December 12, 2025 25 mins

114. How to Start Microdosing with Psilocybin

A science-backed guide to microdosing psychedelics with SetSet’s 12-week protocol, featuring expert insight and lived experience.

Episode Summary

If you’ve been microdose-curious — or maybe you’re already experimenting and want a little more structure — this episode is your map. Host April Pride pulls together insights from SetSet collaborators including author Amy Wong, integrative therap...

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113. Psychedelic Law in Seattle: What’s Actually Legal in 2025?

SetSet Salon breaks down psychedelic law in Seattle with attorneys Perry Salzhauer & Daniel Shortt—what the entheogen resolution covers, what it doesn’t, and the risks it creates.

Episode Summary

Most people think Seattle has legalized psychedelics. It hasn’t—at all. In this episode, recorded live at SetSet’s Psychedelic Salon at Town Hall Seattle, host April Pride sits d...

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112. Epidemic of Fear: How Psychedelics Help Us Transcend Stuckness

Discover how psychedelics help retrain the nervous system to move from fear to flow. April Pride explores the roots of stuckness, the Hero’s Journey, and how microdosing and macrodosing support nervous system healing.

🔵 What You’ll Learn

- Why fear is the defining epidemic of our time—and how it paralyzes potential.

- How Traditional Chinese Medicine, neuroscience, an...

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111. Trip Report: Kanna vs. MDMA Plus How Molly Effs With Your Sleep For Weeks

What if you could feel more connected, relaxed, and joyful—without alcohol or MDMA? In this episode, I talk to Andrew Weisse, founder of getKanna and writer of Substack's The Psychedelic Blog, about the mood-enhancing, heart-opening power of Kanna, a South African plant that’s gaining popularity as a functional empathogen. We discuss its chemical makeup, ...

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110. How to Rethink Drinking Without "Hitting Rock Bottom"

What if your relationship with alcohol doesn’t require a dramatic rock-bottom moment to change? In this episode of SetSet, I sit down with sobriety coach Martha Wright, who went from building a life around wine—professionally and personally—to questioning its role in her daily rituals. Just as I did with cannabis. Together, Martha and I explore what it means to be a “gray ar...

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109. How Psilocybin Microdosing Supports Menopause: A Brain-Based Guide

How can women navigate the emotional, cognitive, and hormonal rollercoaster of perimenopause and menopause? In this episode, April Pride explores how psilocybin microdosing may offer real support for women in midlife. From balancing neuroplasticity and mood to improving sexual function and breaking addictive patterns, this conversation highlights the science, li...

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108. Why Bong Design Matters for Modern Women: Esther Ramirez from Session Goods

What if your bong could live on your coffee table—without shame or splashback? In this 4/20 Easter special, April Pride sits down with Esther Lenore Ramirez, co-founder and CEO of Session Goods, to explore how minimalist bong design supports women who want elegant, intentional tools for cannabis. From design trade-offs (no percs, no ice pinches) to the...

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107. Psilocybin for Menstrual Cycles and Menopause: A Women’s Wellness Protocol

How can mushrooms sync with your cycle—or shift your experience of menopause? In this episode, April Pride is joined by Jennifer Chesak, author of The Psilocybin Handbook for Women, to decode the powerful relationship between psilocybin and women’s hormones. Together, they explore the latest research, ancestral wisdom, and practical strategies for using ...

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106. Natural Psychedelics and the Healing Power of Community

What if the most potent medicine isn’t just the mushroom or the ceremony—but the community that holds you through it? In this soul-stirring conversation, host April Pride continues her dialogue with healer and teacher Satya on the role of natural psychedelics in helping women heal trauma and reconnect with their core selves. From the roots of survival instinct to the chemi...

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105. Integrating Science and Spirituality: A New Framework for Psychedelic Healing

What does it mean to truly heal in a psychedelic space? In this episode, host April Pride is joined by Satya—a seasoned facilitator whose work bridges psychotherapy, meditation, and natural psychedelic therapy. Together, they unpack how conscious language, sacred space, and personalized protocols shape transformative outcomes. From working with trauma...

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104. How Microdosing for Women Rewires Habit, Hormone, and Healing Cycles

How does a microdose change a life? In this powerful conversation, April Pride returns with part two of her interview with guide Sand Symes to unpack what really happens when women begin a psychedelic microdosing protocol. From rewiring somatic patterns to clearing menopausal brain fog, this episode explores how subtle shifts lead to seismic inner changes. San...

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103. Feminine Psychedelic Power: Healing Stories from the Inside Out

In this soulful and story-rich episode, April Pride welcomes Sand Symes, a guide with decades of experience guiding women through psychedelic journeys. Together, they explore how feminine energy—when supported by plant medicine like psilocybin, cannabis, and MDMA—can become a powerful portal to emotional liberation and embodied truth. Through lived experience and c...

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102. Is At-Home Ketamine Treatment Safe for Women with Trauma?

In this powerful second conversation with author and mental health advocate Kaia Roman, host April Pride explores the clinical, emotional, and cultural dimensions of at-home ketamine treatment—particularly for women navigating trauma, depression, and midlife transitions. With brutal honesty and personal insight, the two discuss dissociation, PTSD, accessibility, and whet...

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101. Ketamine for Emotional Healing: Divorce, Depression, and Dosing with Kaia Roman

What happens when your life falls apart—and a new path reveals itself through ketamine-assisted therapy? In this vulnerable and science-savvy episode, April Pride talks with Kaia Roman, author of The Joy Plan, about using ketamine for emotional healing during divorce and lockdown. Kaia breaks down how different types of ketamine administration affec...

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100. 100 Episodes In: What We’ve Learned About Psychedelic Therapy for Women

This milestone episode is a love letter to our listeners. April Pride marks 100 episodes of SetSet by reflecting on what’s changed—and what still needs changing—in the conversation around psychedelic therapy for women. From the rise of ketamine clinics to our monthly psychedelic integration Salons, SetSet continues to fill the critical gaps in education, sa...

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99. Ketamine Therapy for Women: Healing Trauma and Depression at Home

How does healing begin when traditional mental health tools fall short? In this episode, April Pride continues her conversation with Jennifer Whetzel—branding expert, researcher, and founder of the Women in Cannabis Study. Together, they unpack the role of at-home ketamine therapy in treating major depression and PTSD. Jennifer shares the rituals, risks, and reali...

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98. At-Home Ketamine Therapy for Trauma: Jennifer Whetzel on Healing from the Inside Out

What happens when traditional therapies stop working, but the healing isn’t done yet? In this episode, April Pride talks with Jennifer Whetzel—cannabis branding expert and creator of the Women in Cannabis Study—about how at-home ketamine therapy became a powerful tool for processing trauma, managing chronic pain, and rewiring lifelong emotional ...

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97. From Tour Buses to Trauma Work: Rachel Demy on Psychedelic Healing Photography

What happens when a touring photographer turns the camera inward? In this episode, April Pride sits down with Rachel Demy—longtime Death Cab for Cutie crew member turned fine art photographer—to explore how addiction, trauma, and psychedelics shaped her latest solo exhibition. Demy shares how a prescribed medication led to addiction and ultimately spa...

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96. Why Functional Mushroom Coffee Might Be the Future of Wellness

Curious about the magic behind mushroom coffee? In this episode, we’re sharing a feed drop from the Mush Love Podcast hosted by Tim Keck, featuring Wonderground founder Jody Hall. From Cupcake Royale to cannabis edibles to mushroom adaptogens, Jody's journey is one of bold pivots and deep purpose. Tune in as she unpacks the science and story behind functional mushroo...

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95. What’s Really in Your Mushroom Bar? The Truth About Psilocybin Product Safety

What if your “mushroom chocolate” has no mushrooms at all? In this eye-opening episode, April Pride continues her conversation with Joe Robinson, founder of PsiloSafe, to unpack the chaotic world of unregulated psychedelics. They dive deep into psilocybin product safety, how to find a trustworthy facilitator, and why synthetic alternatives like 4-ACO-D...

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