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August 18, 2025 32 mins

Headaches don’t punch the clock at bedtime — in fact, for many, night is when they strike hardest. In this episode, we’ll:

  • Explore how disrupted sleep can trigger and intensify migraines, cluster headaches, hypnic headaches, and chronic daily headache
  • Examine the role of sleep apnea in “morning headaches” and how CPAP therapy can make them disappear
  • Review the latest research linking insomnia treatment to reduced headache burden — including new findings from a Seattle study on prazosin for posttraumatic headache in veterans
  • Break down the brain mechanisms connecting sleep and pain, from hypothalamic circadian control to CGRP signaling
  • Offer practical, research-backed strategies for patients and clinicians to address both sides of the equation

Produced by: Maeve Winter

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Thanks for listening and sleep well!

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