Dr. Ravi Kamepalli made a startling realization that changed everything: bacteria aren't the enemy. As both an infectious disease specialist and wound care physician, he witnessed firsthand how traditional medicine's war on microbes was failing patients catastrophically. In this profound conversation, he unveils his revolutionary "disease triangles" framework that connects our immune system, lipid metabolism, and microbiome in ways that transform how we understand healing.
The statistics he shares will shock you: diabetic foot amputations have a higher five-year mortality rate than breast cancer. While diabetes costs healthcare systems $237 billion annually compared to cancer's $80 billion, we're attacking symptoms instead of root causes. Dr. Kamepalli explains his concept of "energy toxicity" - how excess stored energy triggers inflammatory cascades that turn our own immune systems against us.
Through his personal journey of losing 50 pounds and dramatically reducing his LP(a) levels, he demonstrates that supposedly "genetic" markers are actually nutritionally modifiable. His approach integrates metabolic interventions with wound care, using continuous glucose monitoring, food logging, and remote patient tracking to address the underlying metabolic dysfunction that prevents healing.
This isn't just about wound care - it's about reimagining medicine itself. Dr. Kamepalli advocates for moving beyond "mass medicine mindset" toward personalized, n-of-one healthcare that empowers patients with tools, tracking, and understanding rather than simply prescribing interventions. His vision extends from revolutionizing American healthcare to building sustainable systems in rural India.
BIG IDEA
"We cannot kill bacteria and keep the humans alive - we need to learn how to survive together, and that survival depends on fixing our metabolic dysfunction, not declaring war on microbes."
Dr. Ravi Kamepalli Contact Info
Website: https://nobadbugs.com/
Social Media: @WoundPhysician
Website: ColigoMed.com
Society for Metabolic Health Practitioners SMHP.org
Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table.
Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.
Stay Off My Operating Table on X:
Learn more:
Theme Song : Rage Against
Written & Performed by Logan Gritton & Colin Gailey
(c) 2016 Mercury Retro Recordings
Any use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
Crime Junkie
Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.
Cardiac Cowboys
The heart was always off-limits to surgeons. Cutting into it spelled instant death for the patient. That is, until a ragtag group of doctors scattered across the Midwest and Texas decided to throw out the rule book. Working in makeshift laboratories and home garages, using medical devices made from scavenged machine parts and beer tubes, these men and women invented the field of open heart surgery. Odds are, someone you know is alive because of them. So why has history left them behind? Presented by Chris Pine, CARDIAC COWBOYS tells the gripping true story behind the birth of heart surgery, and the young, Greatest Generation doctors who made it happen. For years, they competed and feuded, racing to be the first, the best, and the most prolific. Some appeared on the cover of Time Magazine, operated on kings and advised presidents. Others ended up disgraced, penniless, and convicted of felonies. Together, they ignited a revolution in medicine, and changed the world.