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September 16, 2025 56 mins

Dr. Ravi Kamepalli made a startling realization that changed everything: bacteria aren't the enemy. As both an infectious disease specialist and wound care physician, he witnessed firsthand how traditional medicine's war on microbes was failing patients catastrophically. In this profound conversation, he unveils his revolutionary "disease triangles" framework that connects our immune system, lipid metabolism, and microbiome in ways that transform how we understand healing.

The statistics he shares will shock you: diabetic foot amputations have a higher five-year mortality rate than breast cancer. While diabetes costs healthcare systems $237 billion annually compared to cancer's $80 billion, we're attacking symptoms instead of root causes. Dr. Kamepalli explains his concept of "energy toxicity" - how excess stored energy triggers inflammatory cascades that turn our own immune systems against us.

Through his personal journey of losing 50 pounds and dramatically reducing his LP(a) levels, he demonstrates that supposedly "genetic" markers are actually nutritionally modifiable. His approach integrates metabolic interventions with wound care, using continuous glucose monitoring, food logging, and remote patient tracking to address the underlying metabolic dysfunction that prevents healing.

This isn't just about wound care - it's about reimagining medicine itself. Dr. Kamepalli advocates for moving beyond "mass medicine mindset" toward personalized, n-of-one healthcare that empowers patients with tools, tracking, and understanding rather than simply prescribing interventions. His vision extends from revolutionizing American healthcare to building sustainable systems in rural India.


BIG IDEA

"We cannot kill bacteria and keep the humans alive - we need to learn how to survive together, and that survival depends on fixing our metabolic dysfunction, not declaring war on microbes."


Dr. Ravi Kamepalli Contact Info
Website: https://nobadbugs.com/
Social Media: @WoundPhysician
Website: ColigoMed.com
Society for Metabolic Health Practitioners SMHP.org


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