Superhero Hormone: What Progesterone Is Really Doing Behind the Scenes

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You’ve heard of estrogen, maybe even LH—but the real superhero in fertility? It’s progesterone.

In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols reveals how progesterone silently supports pregnancy, stabilizes the uterine lining, and prevents early contractions—all without the recognition it deserves.

We break down the science: how progesterone is made from cholesterol, how it converts into testosterone and estrogen, and how granulosa and theca cells work together to build a pregnancy-ready uterus.

Plus, Dr. Amols explains why blood levels may look “low” on vaginal progesterone, why that doesn’t mean treatment failure, and why route of delivery really matters—especially in frozen embryo transfers.

Whether you're trying naturally, doing IUI, or planning an FET, this episode will help you understand what progesterone is really doing behind the scenes—and why it might just be the most important hormone you never thought about.

Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform.

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Join us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.