All Episodes

April 14, 2025 34 mins

In this episode, Dr. Jeremy Pettus and Dr. Steve Edelman go head-to-head in a friendly face-off between two of the most talked-about medications in diabetes and weight management: Ozempic and Mounjaro. Both are part of the powerful GLP-1 class, but which one might be better for you? From A1C reduction and weight loss to heart and kidney protection, ease of use, side effects, and insurance coverage—Drs. E & P walk you through a category-by-category comparison. They bring the clinical data and their own real-world patient experience to help you understand the key differences (and similarities) between these leading therapies. Whether you're managing type 2 diabetes, living with type 1, or exploring options for weight loss, this episode is designed to help you make an informed decision with your healthcare provider.

Key Topics:

  • How These Medications Work: Learn the difference between GLP-1 and dual agonist therapies
  • A1C Reduction: See which drug leads to greater blood sugar improvements based on head-to-head clinical trials.
  • Weight Loss: Discover how much weight patients lose on each medication—and why Mounjaro often shows stronger results.
  • Heart Health: Understand which medication has FDA approval for cardiovascular protection and what’s still under investigation.
  • Kidney Protection: Explore the latest studies showing Ozempic’s ability to slow kidney disease progression.
  • Side Effects: Get practical tips on managing common GI side effects and why titration matters.
  • Ease of Use: Compare how the pens work, dosing flexibility, and what may be easier for patients day to day.
  • Sleep Apnea: Find out how Mounjaro earned a new indication for reducing sleep apnea severity—especially through weight loss.
  • Access for Type 1s: Learn why these meds aren’t yet approved for T1D and how some patients are still getting them.
  • Emerging Indications: Hear about new uses for these meds, including fatty liver, osteoarthritis, and even alcohol reduction.
  • How to Choose: Get expert guidance on which medication may be right for you based on your goals and health needs.
★ Support this podcast ★
Mark as Played

Advertise With Us

Popular Podcasts

Law & Order: Criminal Justice System - Season 1 & Season 2

Law & Order: Criminal Justice System - Season 1 & Season 2

Season Two Out Now! Law & Order: Criminal Justice System tells the real stories behind the landmark cases that have shaped how the most dangerous and influential criminals in America are prosecuted. In its second season, the series tackles the threat of terrorism in the United States. From the rise of extremist political groups in the 60s to domestic lone wolves in the modern day, we explore how organizations like the FBI and Joint Terrorism Take Force have evolved to fight back against a multitude of terrorist threats.

Dateline NBC

Dateline NBC

Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com

NFL Daily with Gregg Rosenthal

NFL Daily with Gregg Rosenthal

Gregg Rosenthal and a rotating crew of elite NFL Media co-hosts, including Patrick Claybon, Colleen Wolfe, Steve Wyche, Nick Shook and Jourdan Rodrigue of The Athletic get you caught up daily on all the NFL news and analysis you need to be smarter and funnier than your friends.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.