In this episode, Dr. Steve Edelman sits down with Michael Killiam, Director of Clinical Services at Pacific Northwest Research Institute, to discuss two groundbreaking studies—TEDDY and Cascade—that have shaped our understanding of genetic and environmental triggers for type 1 diabetes. The TEDDY study, spanning over 20 years and involving nearly 8,800 participants, investigates why some genetically at-risk individuals develop type 1 diabetes while others do not. Cascade builds upon TEDDY’s findings, aiming to integrate early screening into standard healthcare and identify potential preventative interventions. Michael and Dr. Edelman break down the major findings of these studies, including the role of viruses, genetics, and immune responses, and what they mean for the future of type 1 diabetes prevention and treatment.
Key Topics:
- What is the TEDDY Study, and why is it so important?
- Can genetics alone determine who will develop type 1 diabetes?
- How do environmental factors influence the onset of type 1 diabetes?
- Do certain viruses trigger autoimmune attacks on beta cells?
- What did TEDDY reveal about the timing of early autoimmunity?
- Can diet or probiotics help lower the risk of type 1 diabetes?
- What is the Cascade Study, and how does it build on TEDDY’s research?
- How does newborn screening for type 1 diabetes risk work?
- Could vitamin D, Omega-3s, or other supplements slow or prevent type 1 diabetes?
- What’s next in research for type 1 diabetes prevention and treatment?
Teddy Study: https://teddy.epi.usf.edu/
CASCDE study: https://cascadekids.org/
Visit TCOYD's Website for more diabetes edutainment for people living with diabetes: tcoyd.org
**Tune in for two new episodes each month! Like what you hear and want to help us grow? Please rate and review this podcast so we can reach more people living with diabetes!**
Follow our social media channels to empower yourself with the essential areas of diabetes knowledge led by two endocrinologists living with type 1 diabetes: Facebook | Instagram | YouTube
Popular Podcasts
Are You A Charlotte?
In 1997, actress Kristin Davis’ life was forever changed when she took on the role of Charlotte York in Sex and the City. As we watched Carrie, Samantha, Miranda and Charlotte navigate relationships in NYC, the show helped push once unacceptable conversation topics out of the shadows and altered the narrative around women and sex. We all saw ourselves in them as they searched for fulfillment in life, sex and friendships. Now, Kristin Davis wants to connect with you, the fans, and share untold stories and all the behind the scenes. Together, with Kristin and special guests, what will begin with Sex and the City will evolve into talks about themes that are still so relevant today. "Are you a Charlotte?" is much more than just rewatching this beloved show, it brings the past and the present together as we talk with heart, humor and of course some optimism.
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com