An Oil Change for Your Body: Inside Therapeutic Plasma Exchange

We’re not dealing with 'a few toxins' anymore—we’re living in a chemical era our biology was never built for. On this episode of The TBD Fit Podcast, Dr. Paul Savage shares his journey from top trauma physician to a 300-pound, multi-medication patient who didn’t know how to heal himself. He shares how hormones helped him rebuild his health, how he went on to create dozens of hormone clinics and a software company managing millions of patient records, and why treating mold, chronic fatigue, fibromyalgia, and Lyme eventually led him to conclude that 'the toxins had won.'

Dr. Savage explains how modern toxins—microplastics, industrial chemicals, and drug residues—now saturate our environment and our bodies, even before birth. He breaks down why traditional detox methods like binders, chelation, and saunas only remove a fraction of this load, and how therapeutic plasma exchange offers a different solution by physically replacing toxic plasma with clean albumin.  Tune in as we explore real-world reactions in severely ill patients, how MD Lifespan’s protocols integrate avoidance guidebooks, nutrient repletion, stem cells, and exosomes, and why the long-term vision is to make this 'oil change for the body' safer, more accessible, and ultimately less expensive for people who are tired of trying everything and still staying sick.

Dr. Paul Savage is the founder and chief medical officer of MD Lifespan and a board-certified physician with over 25 years of experience in functional and integrative medicine. After a decade as a nighttime trauma doctor at one of the world’s busiest emergency departments, he found himself 300 pounds, on multiple medications, and still getting worse—an experience that pushed him to rethink what real health care looks like.

He went on to build dozens of hormone-focused clinics, create an electronic health records company that handled millions of patients’ data, and launch practices dedicated to some of the toughest chronic conditions, including chronic fatigue, fibromyalgia, Lyme disease, and mold toxicity. When he saw toxins rising faster than traditional detox could keep up, he created MD Lifespan and leaned into advanced tools like therapeutic plasma exchange. Now, he and his team use toxin testing, avoidance strategies, precision nutrients, stem cells, and exosomes to help patients lower their toxic burden and finally feel better.

Dr. Paul Savage, MD

Website: MDLifespan.com/

Instagram: Instagram.com/mdlifespan/?hl=en

LinkedIn: Linkedin.com/in/paul-savage-md-8807869

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