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July 18, 2025 46 mins

In this episode of The Bioactive Nexus podcast, Dr. Bill Clark and Dr. Gene Bruno delve into the critical topic of cognitive function, particularly as it relates to aging and the growingmarket for brain health supplements. They discuss the importance of understanding cognitive function's subdomains, such as memory and attention, and explore the mechanisms of action that underpin various nutraceuticals. The conversation highlights market trends, key ingredients for cognitive support, and the significance of formulation strategies that consider consumer expectations. The episode concludes with insights into future topics, including the role of psychedelics in cognitive health and the importance of gut health for brain function.

Keywords

cognitive function, brain health, nutraceuticals, neuroplasticity, aging, supplements, mechanisms of action, market trends, formulation strategies, consumer expectations

 

Takeaways

·      Cognitive function is crucial as we age.

·      Neuroplasticity allows the brain to reorganizeitself.

·      The nootropics market is rapidly growing.

·      Different mechanisms of action should be used informulations.

·      Realistic consumer expectations are essentialfor product success.

·      Gut health significantly impacts cognitivefunction.

·      Psychedelics are gaining attention in cognitivehealth research.

·      Formulation strategies should avoid the kitchensink approach.

·      Clinically relevant doses are necessary foreffectiveness.

·      Brain health requires a long-term commitment.

Chapters

00:00 Introduction to Cognitive Function and Aging

07:16 Understanding Cognitive Function and Neuroplasticity

12:04 Market Trends in Brain Health Supplements

18:17 Mechanisms of Action in Cognitive Health

20:06 Key Ingredients for Cognitive Enhancement

21:46 Exploring Cognitive Enhancers: Lion's Mane and Ginkgo Biloba

23:21 The Power of Caffeine and Theanine

25:04 Omega-3s and Spermidine: Essential Nutrients for BrainHealth

26:53 Emerging Ingredients: Uridine Monophosphate and PQQ

28:49 The Role of Sage and Nicotinamide Riboside inCognitive Function

30:46 Neuroprotective Polyphenols: Blueberries and Curcumin

32:07 Formulation Strategies: Synergy and Dosing

35:23 Navigating Nootropic Claims: Real vs. Hype

38:56 Building Brand Loyalty Through Realistic Expectations

41:14 Final Takeaways: The Long Game of BrainHealth

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