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September 14, 2025 43 mins

In this episode, Dr. Bill Clark and Dr. Gene Bruno delve into the complexities of inflammation, particularly its role in aging and chronic diseases. They discuss the differences between acute and chronic inflammation, the molecular players involved, and how chronic inflammation accelerates age-related decline. The conversation also highlights the importance of nutraceuticals in managing inflammation and the best practices for formulating effective supplements. The episode emphasizes a proactive approach to health and the significance of evidence-based practices in the nutraceutical industry.


Keywords

inflammation, aging, nutraceuticals, chronic inflammation,health span, supplements, anti-inflammatory, wellness, longevity, immune system


Takeaways

- Inflammation can be both beneficial and harmfuldepending on its type.

- Acute inflammation is necessary for healing,while chronic inflammation is detrimental.

- NFKB is a key regulator in the inflammatoryprocess.

- Oxidative stress and inflammation areinterconnected in a vicious cycle.

- Chronic inflammation is linked to variousage-related diseases.

- Nutraceuticals can help manage inflammationeffectively.

- Using clinically relevant doses in formulationsis crucial.

- Avoid the kitchen sink approach in supplementformulation.

- Proactive health measures can mitigate theeffects of aging.

- Evidence-based practices are essential foreffective nutraceuticals.


Chapters

00:00 Introduction to Inflammation and Aging

07:21 Understanding Acute vs. Chronic Inflammation

14:10 Molecular Players in Inflammation

19:49 Impact of Chronic Inflammation on Aging

20:42 Understanding Chronic Inflammation

21:06 Exploring Anti-Inflammatory Botanicals

22:15 Nutrients and Lipids in Inflammation Management

24:35 The Role of Probiotics in Inflammation

26:25 Innovative Compounds for Inflammation Relief

28:13 The Power of Quercetin

30:00 Best Practices for Formulating Anti-Inflammatory Products

35:07 Proactive Approaches to Health and Inflammation

38:56 Looking Ahead: Future Innovations in Nutraceuticals

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