All Episodes

April 8, 2025 30 mins

We take another break as we are joined by Prof. Wendy Sligl, formidable ID and ICU doc, to discuss the critical topic of optimizing antibiotic prescribing in critical care settings.

The discussion covers various aspects of antibiotic use, including the importance of timely administration, the role of communication in ensuring effective treatment, and the nuances of dosing strategies such as loading doses and continuous infusions. The conversation also delves into the duration of antibiotic therapy, emphasizing the need for individualized treatment based on patient response.

Takeaways:

  • Infections are common in intensive care units, and sepsis is a life-threatening condition.
  • Identifying the clinical syndrome is crucial for appropriate antibiotic therapy.
  • Empiric therapy is often necessary before culture data is available.
  • Timely administration of antibiotics is linked to better patient outcomes.
  • Communication among healthcare teams is essential for effective antibiotic delivery.
  • Loading doses can help achieve therapeutic levels quickly in critically ill patients.
  • Continuous infusions of certain antibiotics may improve clinical outcomes.
  • Shorter courses of antibiotics can be as effective as longer ones.
  • Monitoring patient response is key to adjusting antibiotic therapy.
  • Consulting infectious disease specialists can enhance treatment strategies.

Chapters:

00:00

Introduction to Antibiotic Optimization

01:07

Understanding Infections and Sepsis

02:47

Emergency Room Protocols for Antibiotic Administration

04:56

Identifying Sepsis and Administering Antibiotics

06:33

Communication and Timeliness in Antibiotic Delivery

08:42

Optimizing Antibiotic Dosing Strategies

10:59

Pharmacodynamics and Continuous Infusions

12:44

Duration of Antibiotic Therapy

18:52

Monitoring and Adjusting Antibiotic Treatment

21:39

The Debate on Antibiotic Duration

26:37

Specific Infections and Treatment Duration

31:24

Practical Strategies for Antibiotic Stewardship

32:43

Rapid Fire Questions on Antibiotic Use

Mark as Played

Advertise With Us

Popular Podcasts

24/7 News: The Latest
Crime Junkie

Crime Junkie

Does hearing about a true crime case always leave you scouring the internet for the truth behind the story? Dive into your next mystery with Crime Junkie. Every Monday, join your host Ashley Flowers as she unravels all the details of infamous and underreported true crime cases with her best friend Brit Prawat. From cold cases to missing persons and heroes in our community who seek justice, Crime Junkie is your destination for theories and stories you won’t hear anywhere else. Whether you're a seasoned true crime enthusiast or new to the genre, you'll find yourself on the edge of your seat awaiting a new episode every Monday. If you can never get enough true crime... Congratulations, you’ve found your people. Follow to join a community of Crime Junkies! Crime Junkie is presented by audiochuck Media Company.

The Clay Travis and Buck Sexton Show

The Clay Travis and Buck Sexton Show

The Clay Travis and Buck Sexton Show. Clay Travis and Buck Sexton tackle the biggest stories in news, politics and current events with intelligence and humor. From the border crisis, to the madness of cancel culture and far-left missteps, Clay and Buck guide listeners through the latest headlines and hot topics with fun and entertaining conversations and opinions.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.