Could a simple gas naturally produced in your body be the key to preventing heart disease, dementia, cancer, and sexual dysfunction? Dr. Nathan Bryan, a pioneering biochemist who has spent nearly three decades researching nitric oxide, reveals why this molecule is fundamental to human health and longevity.
After the 1998 Nobel Prize recognized the importance of nitric oxide, scientists began to understand its essential role as a vasodilator that keeps blood flowing freely throughout our bodies. Dr. Bryan explains how this critical gas production naturally declines with age, but can be accelerated by modern lifestyle factors including processed foods, sugar consumption, antiseptic mouthwash, fluoride exposure, and pharmaceutical drugs – particularly proton pump inhibitors like Prilosec and Nexium.
The conversation takes a fascinating turn when Dr. Bryan connects the dots between oral health and systemic disease. He presents compelling evidence that root canals and dental infections may contribute to cancer development by creating environments of low oxygen, low pH, and disrupted energy pathways. This controversial but evidence-backed perspective challenges conventional medical and dental practices while offering new hope for disease prevention.
Most importantly, Dr. Bryan provides practical, actionable strategies to maintain and restore healthy nitric oxide levels. He cautions that most marketed "nitric oxide supplements" are ineffective placebos, and instead recommends specific lifestyle changes: eliminating sugar and processed foods, increasing green leafy vegetable consumption, avoiding fluoride products and antiseptic mouthwash, practicing intermittent fasting, and getting regular sun exposure.
Whether you're concerned about cardiovascular health, cognitive function, metabolic disorders, or simply want to optimize your wellness and longevity, this eye-opening conversation provides critical information that could transform your understanding of health and disease prevention.
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Transcript
Episode Transcript
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Speaker 1 (00:00):
You can't do it to the heart, you can't do it to
the brain, the liver, the lungs,every organ in the body.
And then, number two, you startto see an increase in blood
pressure and because nitricoxide is a vasodilator, it's
opening up the blood vessels.
So now you're.
If you lose the ability to makenitric oxide, you become
chronically constricted.
Now you've got the same volumeof blood going through smaller
(00:22):
pipes, if you will, and thatcauses an increase in blood
pressure.
Speaker 2 (00:26):
Basic physics Hello everyone, thank you for joining
me today.
I took a long break, but it'swonderful to be back.
This episode I want to presentto you in such an eloquent way.
(00:48):
He is world-renowned researcher, dr Nathan Bryan, somebody
that's dear to me, an incrediblyessential human being.
Dr Bryan is doing God's workand he has helped so many people
understand the essentialimportance of nitric oxide.
He's recently released a book,the Secrets of Nitric Oxide, and
(01:13):
on this show today we're goingto dive right into it and how
important it is to live and Imean that to live.
It's such an important asset ofour body and he's going to
explain to us what nitric oxideis, why we're deficient in it,
how do we know if we'redeficient and, if we are, what
are the causes, what are thesymptoms and how can we get it
(01:34):
back.
So thank you for joining me andI'm very excited to show Dr
Nathan Bryan, phd on nitricoxide.
All right, dr Brian, it's sonice to have you on my podcast.
It's an honor.
I love your work, I follow yourwork and I appreciate you, and
I'm very, very grateful that youaccepted my invitation.
(01:57):
So thank you.
Speaker 1 (01:59):
Thank you, those are kind words and I appreciate this
and honor and invite for the.
You may invite me to be withyou, so I'm looking forward to
it.
Speaker 2 (02:07):
Absolutely All right, let's get into this amazing
conversation of nitric oxide.
So how did you get into thisfield?
You have a PhD.
You've been studying this formany, many years and have worked
with hundreds and hundreds ofpatients.
So tell us what is nitric oxide?
Speaker 1 (02:26):
Well, you know it's a fascinating molecule.
It's a gas that's naturallyproduced in the body.
The odor we get, the less wemake, and that's what's
responsible for age-relateddisease.
But I was first introduced tothe science of nitric oxide in
the late 90s, early 2000s, whenI was a student at LSU School of
Medicine.
They were working on a PhD inmolecular and cellular
physiology and a Nobel Prize hadjust been awarded in 1998 for
(02:50):
the discovery of nitric oxide.
So you know it was an excitingtime.
Everybody had a lot of promisefor this molecule, that it had
really the potential to changethe world, of managing chronic
disease, even preventing a lotof the poorly managed chronic
disease that we're still dealingwith today.
And so that's how I gotintroduced to this.
And you know, fast forward 30years, 25 years Now, here we are
(03:15):
.
We've made a lot of discoveries.
So there's over 200,000scientific papers published in
the nitric oxide literature.
So you know we understand a lotmore today about nitric oxide
certainly than we did 25 yearsago.
Speaker 2 (03:24):
So when you say that as you get older, that your body
produces less nitric oxide,from what age are we looking at?
Speaker 1 (03:36):
We know it's quite variable and so let me just
preface that by saying there'sreally two ways the body makes
nitric oxide.
There's an enzyme in the liningof the blood vessel and when we
talk about this age-relateddecline in nitric oxide
production, it's really lookingat the function of the enzyme
that typically makes nitricoxide from L-arginine.
That's called the NOS pathwayand so it's similar to.
(03:59):
You know you can kind of mirrorthe effects we see in human
growth hormone.
You know it peaks kind of inour teens and then just steadily
declines as we get older.
But there are many things thatcontribute to a loss of nitric
oxide production in terms of thefunction of that enzyme.
But today we know that we don'tnecessarily see that age-related
(04:20):
decline.
We can prevent it, we canprolong it or we can accelerate
it.
Related decline we can preventit, we can prolong it or we can
accelerate it.
So to answer your question, youknow today there are 18, 20, 24
year old kids and young peoplethat have the nitric oxide
production of a 60 or 70 yearold and we have people like, for
instance, I'm 51, and I havethe kind of the nitric oxide
(04:40):
production potential of someonein their 30s production
potential of someone in their30s.
So we can you know it's not astatic kind of concept, but it
depends upon diet, it dependsupon lifestyle, it depends upon
what you put in your body, onyour body and how you really go
about every day, but it's theWestern lifestyle diet, physical
inactivity, pharmaceuticaldrugs, antacids, fluoride,
(05:03):
antiseptic mouthwash,antibiotics all of those lead to
a loss of nitric oxide or anaccelerated decrease in nitric
oxide production.
Speaker 2 (05:12):
Now I want to ask these two questions.
You said food has an impact onnitric oxide, so does this mean
that whether you eat organicfood or grass-fed meat, do all
of these play a factor in thedecrease of nitric oxide?
Speaker 1 (05:31):
They do.
And so what we're finding isthat diet really serves two
functions.
Number one you've got toeliminate things in your diet
that are inhibiting nitric oxideproduction, and then you've got
to start including things inyour diet that can enhance or
stimulate and activate nitricoxide production.
So then you got to startincluding things in your diet
that can enhance or stimulateand activate nitric oxide
production.
So really, the biggest culpritin inhibition of nitric oxide is
(05:51):
sugar.
So you know, we we wereconsuming way too much sugar in
the Western world and simplecarbohydrates.
So simple, elimination of sugar.
You know, we explained thisbecause sugars, or glucose, is
like glue right, it's the rootword of glucose.
It's a glue, it sticks thingstogether.
So when you have an elevationin fasting or blood glucose
(06:14):
levels, that molecule, thatsugar, sticks to things like
hemoglobin, and we measure thatas hemoglobin A1C.
But it also sticks to enzymes,and enzymes in biochemistry and
enzymology are designed toundergo conformational change to
transfer electrons throughdifferent domains of an enzyme,
and if there's too much sugar onthere, it's stuck in a single
conformation so that enzymecan't do its job.
(06:37):
So that's number one you have toeliminate sugar,
sugar-containing supplements,sugar-containing foods and then
start to increase theconsumption of green leafy
vegetables, healthy fats, a lotof protein.
Now, you know, the older we getthem, the higher consumption of
protein that's required toprevent muscle loss and bone
loss.
So those are the biggies.
(06:58):
And I'm not a big fan ofhardcore vegan, hardcore
carnivore, keto.
But I think the most importantthing is eliminate carbs and
sugar and then, you know, eat abalanced diet in moderation Lots
of protein, good fats, verylittle carbs.
Speaker 2 (07:14):
What are some of the symptoms a person can experience
if their nitric oxide isdecreasing?
Speaker 1 (07:20):
Yeah, you know, we've come a long way in
understanding that, and that's areally important question
because it's not part of yourstandard lab.
So if you go to your physicianor healthcare practitioner and
they want to draw blood, thereis no option.
For what is my nitric oxidelevels?
Right, because it's a gas.
Once it's produced, it's gonein less than a second.
So we have to rely on symptomsand the presentation of symptoms
(07:42):
in people.
So usually the first thing thatyou see and experience when your
body has the inability toproduce sufficient nitric oxide
is sexual dysfunction orerectile dysfunction.
That occurs in both men andwomen, because in order for
women to have an orgasm or mento have an erection, we have to
dilate the blood vessels of thesex organs, and that's done
(08:02):
through the production of nitricoxide.
So if we've lost the ability toproduce nitric oxide, we don't
get dilation, we don't getencouragement, women become an
orgasmic and men can't get anerection.
So that's number one and that'swhat we call the canary in the
coal mine, because if you can'tproduce nitric oxide and
regulate blood flow to the sexorgans, you can't do it to the
heart.
You can't do it to the heart,you can't do it to the brain,
(08:22):
the liver, the lungs, everyorgan in the body.
And then, number two, you startto see an increase in blood
pressure.
And because nitric oxide is avasodilator, it's opening up the
blood vessels.
So now you're.
If you lose the ability to makenitric oxide, you become
chronically constricted.
Now you've got the same volumeof blood going through smaller
(08:42):
pipes, if you will and thatcauses an increase in blood
pressure.
Basic physics so, an increase in.
Two out of three Americans havean unsafe elevation in blood
pressure.
So that should tell you howmany people are nitric oxide
deficient.
And then, number three, youstart to get metabolic disease,
things like glucose and insulinresistance, type two diabetes,
(09:04):
because in order for insulin towork in the cell and for that
cell to bring in glucose andclear it from the circulation,
it requires that cell to be ableto produce nitric oxide.
The nitric oxide is part of theinsulin signaling pathway and
responsible for glucose uptake.
And then, number four, youstart to develop exercise and
tolerance.
If you can't walk up a flightof steps or do basic exercise
(09:26):
without becoming windedtightness of chest, then your
body can't make nitric oxide.
And then, fifth, you start toget dementia and.
Alzheimer's.
We and others have discoveredthat really Alzheimer's disease
is a symptom of nitric oxidedeficiency.
It's lack of cerebral bloodflow, it's insulin resistance,
it's type three diabetes, andnitric oxide corrects all of
(09:48):
those.
So if you maintain normalperfusion, you don't get the
focal ischemia, you can maintainnormal glucose uptake in the
brain.
You don't get misfolding ofproteins.
So there's no taut angles,there's no amyloid plaque built
up and all that can be correctedby maintaining optimal nitric
oxide levels.
Amyloid plaque built up.
Speaker 2 (10:05):
And all that can be corrected by maintaining optimal
nitric oxide levels.
Exactly and what I noticed.
Now I want to get into theproton pump inhibitors.
I want to talk about that?
Yeah, because some of thesymptoms that you just described
that occur from decreasing thenitric oxide.
Do they prescribe these protonpump inhibitors to help with the
situation?
Look, I've never understoodthis type of drugs.
Speaker 1 (10:31):
Now look the standard of care in Western medicine and
I think it's kind of gone allover now but if you're admitted
to the hospital, and it doesn'tmatter if it's from trauma or
influenza-like illness or moreserious critical conditions such
as a heart attack or stroke.
And it doesn't matter if it'sfrom trauma or influenza-like
illness or more serious criticalconditions such as a heart
attack or stroke.
The first thing they do is giveyou omeprazole.
Speaker 2 (10:51):
Yes.
Speaker 1 (10:52):
Prilosec and proton pump inhibitors, and so to me
it's no wonder that people getworse when they're admitted into
a hospital and very few peopleget better, because if you've
ever been to the hospital andeaten hospital food.
It's I mean it's.
It's criminal.
But even more criminal isgiving these patients proton
(11:13):
pump inhibitors without any realindication, and these are only
approved for gastroesophagealreflux disease.
But here's what happens If youput patients on a PPI they can't
absorb nutrients things likemagnesium, iron, selenium,
chromium, iodine, b vitamins andyou can't break down proteins
into amino acids.
So you start to developfoodborne allergies and you
(11:35):
can't regulate acid base balanceand you become acidotic.
We saw this in COVID from thehypoxemia and the acidosis from
admitted COVID patients.
So giving PPIs is the worstidea in the world that I could
think of as a biochemist andphysiologist.
But you would only give them ifyou wanted to make your
patients sicker.
So there's a host of bad thingsthat happen with inhibiting
(12:00):
stomach acid production.
I mean, secretion of stomachacid is probably one of the most
fundamental critical aspectsabout human physiology.
But it's also these drugs arecompletely in shutting down
nitric oxide production andagain we like to start with
important clinical observationsand then work back to figure out
mechanism.
But if you just look at theclinical data and these drugs,
(12:22):
have been on the market fordecades now, and it was clear
that if you've been on a protonpump inhibitor and these drugs
have been on the market fordecades now and it was clear
that if you've been on a protonpump inhibitor and these are
things like Prilosec, prevacid,nexium, omeprazole, pantoprazole
those are the prescriptionmedications Now you can get them
over the counter.
If you've been on those drugsfor three to five years, what
the clinical data tell us isthat you have a 40% higher
(12:43):
incidence of heart attack,stroke and Alzheimer's.
Speaker 2 (12:46):
Alzheimer's Right.
I was reading your yeah, yeah.
Speaker 1 (12:49):
So yeah, I mean, we have to do better, we can do
better.
And it's just.
The data are very clear.
Now we just have to apply thepressures.
You know these drugs shouldhave black box warnings on them
because they're dangerous andthey should be taken off the
market.
I think these drugs are moredangerous, more deadly, than the
COX-2 inhibitors from the early2000s that were killing people
(13:11):
left and right from heart attackand stroke and taken off the
market for a brief time.
But now they're back on themarket with a clear black box
warning that these drugs cancause heart attack and stroke,
and the same thing should beacknowledged for proton pump
inhibitors.
Speaker 2 (13:32):
I was watching a few of your podcasts and one thing
that you had said is, I think,that we're afraid of acid in our
body.
We try to contain that as muchas possible, but, understanding
your work, what you're sayingit's needed Because if we don't
have it, then our supplementsare like magnesium and so are
not going to be breaking downproperly in our body.
Can you explain us?
You know a little bit aboutthat.
(13:53):
Yes, so the gastrointestinalsystem.
Speaker 1 (13:55):
First of all, the human body is a lot smarter than
we are.
It knows what to do under allcircumstances.
We just got to get out of theway.
So here's how normalgastrointestinal physiology is
designed to work.
When we eat food, we getnutrients from our food.
This is the basic parts ofenergetic and converting food we
eat into cellular energy.
(14:15):
We need stomach acid to absorbthings like B vitamins,
magnesium, selenium, iron,chromium, iodine.
So if we can't make stomachacid, then when we consume these
foods that contain thesenutrients, they just pass right
through.
You know, the gi tract from themouth to the anus is the outside
world.
I mean, it's a hollow type thatgoes hollow pipe that goes
(14:38):
straight through us.
It's the outside world.
Yeah, so our gi system, ourepithelial cells, our gastric
mucosa and the lumen of thestomach, those different
environments are designed toabsorb specific nutrients.
Along passage from the stomachto the duodenum, the jejunum,
small intestine, largeintestines, colon At different
stages of digestion, there'stransporters that take up
(15:01):
nutrients from the food and thenput it inside our body so that
our cells can use it.
So that's number one.
Number two is that for thepancreas, the exocrine pancreas,
to secrete sodium bicarb, whichis the buffer system to make
sure that our body maintains anormal pH of 7.4 and an
electrical potential of minus 25millivolts across the cell
(15:22):
membrane.
we have to secrete sodium bicarbfrom the pancreas, and the
signal to tell the pancreas tosecrete sodium bicarbonate is
the acid dump from the lumen ofthe stomach.
So if our body's not makingstomach acid, the duodenum, the
early part of the smallintestine, doesn't detect and
get the signal.
Hey, I need to secrete somesodium bicarb and that's the
(15:44):
acid-based buffering and theacid-based system for
maintaining normal cellularpotential voltage and pH.
So this leads to a hallmark ofa number of problems.
And then the other thing isthat you can't break proteins
into amino acids.
So you know, we make humanproteins.
We're never designed to take onanimal proteins or plant
(16:06):
proteins.
Speaker 2 (16:07):
Really.
Speaker 1 (16:08):
Proteins are made up of amino acids.
Right, so when we consume plantprotein or animal protein, the
purpose of the stomach and itsacidity is to activate an enzyme
called trypsin, which thencleaves that peptide bond and
releases amino acids.
So now the amino acids can beabsorbed in the small intestines
(16:30):
and then we transport thoseinto the cell and we make human
proteins out of those basicamino acids.
But if you don't have stomachacid, you can't break those down
.
Now you have peptide fragmentsthat are absorbed across the gut
.
You lose the integrity of thebarrier, the epithelial cells,
and now your body sees this as aforeign substance and it makes
antibodies against it because itdoesn't recognize foreign
(16:53):
proteins or foreign peptidefragments.
And for me that's the basis ofall foodborne allergies.
You know, when I was a kid inschool we didn't have kids with
peanut allergies, milk allergies, all these allergies.
And because I think it's whenkids throw up or spit up as a
baby, what do you do?
The pediatrician gives them anantacid and now that makes them
(17:13):
prone to foodborne allergies,because they can't break down
milk proteins, they can't breakdown proteins like gluten and
peptides, so they developintolerance to them and
foodborne allergies are born.
So nitric oxide is important,obviously for a number of
reasons, but we have to get awayfrom inhibiting stomach acid
production.
(17:34):
I think it's what's leading tomost of the symptoms and
syndromes and things today.
Speaker 2 (17:39):
My goodness, dr Bryan , can we get into the four
hallmarks of disease?
I think this is such animportant matter to kind of
address If you briefly explainto us what they are so we can
understand them better.
Speaker 1 (17:55):
Well, you have to kind of take a step back and
look outside of how medicine ispracticed today, because
everything is siloed right.
So if you've got a heart orvascular issue, you go to your
cardiologist and he's onlyfocused on your heart and blood
vessels.
Yes, please, neurologist, butyou got to remember everything
is connected.
And so whether you're lookingat heart disease, liver disease,
(18:27):
kidney disease, neurologicaldisease, when you step back and
look, there's always commondenominators and those four
hallmarks are low blood flow tothe organ.
So in cardiovascular disease weget a buildup of plaque in the
coronary arteries and you get anobstruction of blood flow and
we develop ischemic heartdisease In the brain, whether
it's Alzheimer's, parkinson's,adhd, bipolar, through imaging,
(18:50):
spec scans, functional MRIs, wesee that there's a loss of
regulation of blood flow to thebrain.
So number one, it's low bloodflow.
And then number two isinflammation.
We know inflammation is whatdrives chronic disease.
Number three is oxidativestress.
And then, number four, we startto develop immune dysfunction.
And so if you go back and now,mechanistically and we and
(19:10):
others have discovered for thepast 25 years if you can prevent
the age-related decline innitric oxide production, you
maintain normal perfusion of theorgan.
It inhibits inflammation.
In fact I've got a number ofissued patents that are on
(19:31):
methods of reducing inflammationby nitric oxide and we
completely inhibit the oxidativestress that occurs we see in
most disease processes and wemitigate the immune dysfunction.
So simply by giving nitricoxide or restoring the
production and signaling ofnitric oxide, you're addressing
the hallmarks of every singlechronic disease.
Speaker 2 (19:51):
I think what I have learned from reading so much
about research like howessential blood flow is in a
person's body.
Speaker 1 (19:56):
That's right.
Yeah, it's blood flow, and it'soxygenation.
So there's two things it'shypoxia, which means low oxygen,
or it's ischemia, which means adisruption in the blood supply,
whether there's oxygenatedblood or not.
So ischemia occurs when there'san obstruction, either a
thrombus or an embolism.
That's what happens in ischemicstroke or an acute MI there's
(20:17):
an occlusion of the bloodvessels.
There's no blood flow gettingin, it's a roadblock.
The other problem and weexperienced this, this during
COVID was the hypoxemia.
So you may have adequate bloodflow and circulation, but the
hemoglobin, the oxygen carryingcapacity of the red cell, is
compromised.
And again, all that iscontrolled by nitric oxide.
Nitric oxide dilates the bloodvessels to improve circulation
(20:41):
and it's how we oxygenatehemoglobin in red blood cells.
So nitric oxide controlseverything we know about
circulation and tissueoxygenation.
Speaker 2 (20:52):
Earlier we were talking about heart disease and
heart attacks.
Are those also caused by thelack of nitric oxide in the body
, like high blood pressure?
Because number one killer rightnow is heart disease and heart
attack right.
Speaker 1 (21:07):
It has been for the past 100 years.
Speaker 2 (21:09):
Yeah, so what are some things that people can do
to prevent that?
I mean, what can we do to havemore nitric or maintain our
nitric oxide?
Speaker 1 (21:19):
Well, I'll just answer the first question.
The first question is yes.
So when we lose the ability tomake nitric oxide the functional
loss of the endothelial cells,which are the cells that line
all blood vessels throughout thebody when those endothelial
cells lose the ability toproduce nitric oxide, you start
to get an upregulation ofadhesion molecules and then
monocytes, neutrophils.
(21:40):
Cholesterol starts sticking andit's transported across the
endothelium into the intima.
Cholesterol starts sticking andit's transported across the end
of the limb into the intima.
You get smooth musclehyperplasia, intima media
thickness and you start toocclude the lumen of that blood
vessel.
And then that starts theinflammation, oxidative stress
and immune dysfunction.
So that functional loss ofnitric oxide occurs years,
(22:00):
sometimes decades, beforethere's ever a significant
occlusion or stenosis of, forinstance, the corneal arteries
or the carotid arteries.
But then and the otherimportant thing about is this
nitric oxide can actuallystabilize plaque.
It can prevent the plaque fromfrom occurring in the first
place.
But it's really not the degreeof stenosis that causes the
(22:21):
problem, it's the vulnerabilityof the plaque.
Stenosis that causes theproblem.
It's the vulnerability of theplaque.
And about 50% of heart attacks,sudden cardiac death, in America
, is in patients who have lessthan 50% stenosis of the
coronary arteries.
So it's the vulnerability theygot vulnerable plaque that
erupts.
Now you've got a thrombus andan embolus that goes down, clogs
(22:41):
up those coronary arteries andthat's acute MI or myocardial
infarction, and many peopletheir first sign is sudden
cardiac death and there's nogoing back from that.
So what we have to do is wehave to maintain adequate nitric
oxide production so you don'tget plaque deposition, you don't
get plaque instability and youdon't have an eruption of that
(23:01):
plaque and causing acute MI.
So it goes back tounderstanding number one, how
the human body makes nitricoxide, and then further
understanding of what's causinga loss of the natural production
of nitric oxide.
Then, and only then, can youstart to kind of suggest or
recommend therapeutic strategiesto restore nitric oxide.
So we've touched on those alittle bit.
(23:22):
I mean you have to get rid ofantacids, you have to get rid of
antiseptic mouthwash and Maybethat's probably a nice segue
into this other pathway, becausewe discovered that the oral
bacteria are responsible forproducing nitric oxide.
So anything that destroys oralbacteria fluoride, toothpaste,
and really fluoride it's nottoothpaste, it's the fluoride in
(23:44):
the toothpaste.
Or things like Listerine, scope, antiseptic mouthwash,
chlorhexidine those kill.
When you see the commercials,it says this kills 99.99% of the
bacteria.
You should believe them,because it does, and that's not
a good thing.
By the way, we have to we, nowthat the entire microbiome
project has been mapped out andwe know that the bacteria that
(24:06):
live in and on our bodyoutnumber our human cells 10 to
1.
We need to maintain a healthymicrobiome.
We don't need to kill it, weneed to support it, and so
things like mouthwash arecompletely disrupting nitric
oxide production.
We and others have publishedthat to use mouthwash, your
blood pressure goes up, you losethe protective benefits of
exercise, and so it's just badnews.
So get rid of mouthwash,eliminate fluoride, wean off
(24:30):
antacids, and then it's justcommon sense moderate physical
exercise, 20, 30 minutes ofdirect sunlight exposure day,
and then a balanced diet, inmoderation no sugar, few carbs,
healthy fats, a lot of proteinand throw in some green leafy
vegetables.
Speaker 2 (24:50):
What about some foods ?
I mean, yes, those are going tohelp the nitric oxide, but what
are some foods that we shouldstay away?
Speaker 1 (24:54):
from yeah, the white foods, bread, dairy, anything
that leads to an increase inBread, dairy, kind of your white
foods, your high glycemic indexfoods.
Speaker 2 (25:06):
What about sourdough?
Because I have a lot of momsthat make sourdough bread from
starter, you know.
So it's an important thing forus to know.
Speaker 1 (25:15):
I think it's difficult to say because
everybody's different and itdepends upon kind of your
metabolic flexibility.
And now the beauty of thesecontinuous glucose monitors you
can monitor in real time and aslong as you don't see a rapid
increase in your blood glucoselevels, you stay away from
things that cause a spike inglucose Because, as I mentioned,
(25:36):
an elevation, a prolongedelevation in glucose leads to
vascular dysfunction, leads toloss of nitric oxide production.
So just do an experiment onyourself, get you a continuous
glucose monitor.
Eat things, monitor your bloodsugar and if you have good
insulin sensitivity, then itshouldn't lead to an increase in
blood sugar that persists andlasts for many, many hours, like
(25:58):
it does in type 2 diabetics.
So, everybody's different but Ijust respond to what I know my
body tolerates and I listen tomy body and if it's insulting
and makes me feel bad then Itypically don't eat it again.
I'm too busy to feel bad.
Speaker 2 (26:12):
So there's bread and then there's processed food.
What else?
Speaker 1 (26:16):
Yeah, I mean mainly it's sugar, your simple
carbohydrates, processed foods,like you know anything that any
food product that's notrefrigerated it can sit on a
shelf for weeks, months or years.
It's probably not good for you,right?
Because food real food willspoil over time, and you've
(26:37):
probably seen it.
You know people that buy theMcDonald's food and leave it out
on the shelf for years and itdoesn't spoil.
I mean, ants won't even eat it.
I mean, we got to look atnature, right, that's true.
If ants don't touch it, it'sprobably a pretty good
indication that it's not realfood.
And so that's the McDonald'sexperiment.
Speaker 2 (26:54):
What about oils?
Dr Bryan, what oils do yourecommend?
That's good for us.
Speaker 1 (26:59):
Yeah, certainly you got to stay away from seed oils.
I mean we need, you know, oliveoil, kind of natural oils,
avocado oil, ghee, beef tallow.
Because the seed oils we got toremember and this goes back to
basic cell biology every cell iscontained within a cell
membrane and that phospholipidbilayer is made up of fats,
(27:23):
cholesterol, triglycerides,fatty acids.
And these seed oils, theseomega-6, really affect the
membrane fluidity and now welose the control of what's going
on outside and inside becausethere has to be intracellular
signaling.
The outside of the cell gets asignal and there's this seven
transmembrane signalingmechanism that depends upon cell
(27:45):
membrane fluidity.
And if we lose that, we losethe intracellular signaling
inside the cell and cells becomedysfunctional.
We develop disease and thehalf-life of these seed oils
canola oil, corn oil, vegetableoil is about 600 days, almost
two years, and what that meansis if you consume a seed oil, it
(28:06):
takes about two years for halfof it to be excreted out of your
body.
Speaker 2 (28:10):
Oh, my goodness.
Speaker 1 (28:11):
And really we need about five half-lives to
completely eliminate somethingfrom the body.
So seed oils stay around forabout 10 years and they're
causing damage, they're causingdiabetes, they're mitochondrial
toxicants, they're losing thebody's ability to communicate
cells in the body to communicatewith one another.
So we have to avoid those cellsin the body to communicate with
(28:33):
one another, so we have toavoid this.
Speaker 2 (28:34):
Dr Bryan, there has been such a high rise in cancer
rates among men and women intheir 20s, in their 30s.
I watched a recent podcast ofyours when you were talking
about you have treated hundredsand hundreds of patients and
every single one of them had ayou know something going on,
(28:55):
like whether that's I don't knowa cavity or root canal.
So can you, can you brieflytalk to us about that?
Like is, is cancer or havingproblems orally?
Is it related?
How does that relate to cancer?
yeah, it's a confusing thing,but you know.
Speaker 1 (29:13):
Yeah, you can see that that one little clip on
Instagram has hundreds ofthousands of comments and shares
and you know some really somepretty bitter and nasty
responses that you know I'vekind of fallen off the wagon and
I don't know what I'm doing.
But no, that means you're,you're making an impact because
this is thinking.
It's a completely new paradigm.
(29:34):
So, number one, I'm not aphysician.
I don't treat patients, butwhat I do is, you know, people
call me, people that are sickand chronically ill, that the
standard of care and theconventional medicine has failed
them, and so people come see meand I just give them what I
know about human physiology andbiochemistry.
But when these people, thesechronic patients that are sent
(29:55):
home to die, they've gonethrough surgery, chemo,
radiation, the standardtreatment of cancer, and even MD
Anderson will tell you they'venever cured a person of cancer
their goal is to make you diewith cancer and not make you die
from cancer.
Speaker 2 (30:13):
I mean, what a low bar right, there's a word that I
had a water scientist.
He said if the disease won'tkill you the cure will kill you.
Speaker 1 (30:28):
No, that's exactly what happens in oncology today,
and it should be criminal.
And here's the problem In everyoncologist and I've gone to the
oncologist appointments withmany of these patients that I've
developed a oncologist, andI've gone to the oncologist
appointments with many of thesepatients that I've developed a
friendship with and I simply goin and ask the tough questions
that the family obviously isn'taware of or educated enough to
ask important questions.
And I go what caused thispatient's cancer?
And no one can answer that.
(30:49):
And so my question is how inthe hell are you going to treat
something if you don't know whatcaused it?
And so every cancer is looked atthe same, but we're going to
cut it out, we're going toradiate the shit out of it.
Which radiation causes cancerin the first place?
You're going to get a toxicchemotherapeutic agent that's
going to kill all rapidlydividing cells, including those
of the gut, including those ofthe hair follicles, and we're
(31:10):
going to make you extremely sickand actually make you want to
die.
That's what I've witnessed.
People get cancer treatment.
They want to die because thelife they're living, the quality
of life, is awful, and thosethat believe you know they're
going to go on to an everlastinglife, so what we have to do is
what again look at the clinicalhallmarks of cancer and Otto
(31:32):
Warburg, in the 1920s and 30s,discovered that cancer is a
metabolic disease and he wasawarded a Nobel Prize.
It's called the Warburg effectbecause cancer cells only thrive
, replicate, proliferate in alow oxygen, low pH environment
through mitochondrialdysfunction.
So then you got to ask yourselfwhat is causing the metabolic
disease?
(31:52):
So nine out of 10 Americanshave metabolic or metabolically
challenged, meaning they're notmetabolically healthy, and
that's the first step in therapid progression of cancer.
So then you got to ask yourselfwhat's leading to that?
So the issue of oral hygiene.
You know it's been known forover 100 years now that people
with gingivitis, periodontaldisease, oral dysbiosis, have
(32:14):
about a 10-time higher risk ofheart attack, stroke and
all-cause mortality, and we callthat the oral systemic leak.
But let's talk about the rootcanals in cancer.
Speaker 2 (32:25):
Yes.
Speaker 1 (32:26):
And if you go and you have to understand what a root
canal is, If you develop atoothache, you go to the dentist
, they'll typically refer youout to the dentist, they'll
typically refer you out to anendodontist and you've got an
infection right.
You've got nerve cells in theroot of the tooth that are
sensing pain and that pain istypically if it's not from
trauma, it's from bacterialtranslocation and an infection.
(32:48):
So what they do is they take thenerve root out of the tooth.
It's a root canal.
They canal down, they take theroot out of the tooth, so now
you no longer feel the pain, andthey also remove the blood
supply to that tooth.
And then they send you home andput you on an oral antibiotic.
And they must have forgottenthat 10 minutes before that they
(33:09):
took out the blood supply tothat infected tooth.
So the oral antibiotic, it goessystemic but it's not getting
to the site of infection.
So now you still have aninfected tooth, but now you've
got dead tissue, because withoutnerve supply and without blood
supply, that tooth, that tissue,that crystalline tissue in your
(33:30):
head, is now dead.
And dentists are the onlyprofessionals who think it's
okay to leave dead tissue in thebody.
If you develop a gangrenous toeor foot and you don't get rid
of it or don't amputate it.
Speaker 2 (33:46):
It will kill you.
Speaker 1 (33:48):
But yet they think it's okay to leave dead teeth in
the body and expect people tolive a happy life, and that
doesn't happen.
And so, number one, you've gotan asymptomatic infection in
that root canal tooth.
And these bacteria, they'reanaerobes, so they don't need
oxygen, but they're just eatingand metabolizing and spitting
out toxins.
And this goes back to reallytraditional medicine, ayurvedic
(34:12):
medicine, where it's known thatevery tooth, these acupuncture
meridians, are connected to anorgan and so the teeth are like
circuit breakers.
And if you've got a disruptionin that meridian you don't get
voltage, you don't get electronflow, you don't get nerve
conductance in that meridian.
And what happens?
Low voltage, low voltage, lowph, low oxygen, and that's
(34:35):
cancer.
My goodness, I'm shocked, yeah,and I tell you know, when people
come to see me no, that's thefirst thing I say and a lot of
people look at me like I've,I've lost my mind.
They go look, I don't have atoothache, I got cancer, help me
.
And I go look, the reason youmay have cancer is just go and
let's, let's figure step by step.
(34:55):
But I made a kind of a profoundcomment in that one podcast I
did and said the people thatcome to me with solid tumors
with metastatic disease.
I've never seen anybody that Ididn't send to a dentist and
people on that commented andthey go I've gone to the dentist
and I don't have any dentalinfections and I've had cancer
and I still got cancer.
(35:16):
Well, their dentist is lookingat an x-ray and sending them.
Oh, the x-ray comes back clear,it's unremarkable.
Well, an x-ray is not going topick up the radiolucency of an
asymptomatic osteo-necroticinfection in the jawbone so you
have to do a CT scan or a 3Dcone beam.
So if you go and let them doand it's not always a root canal
(35:36):
right Root canals are a problembecause 100% of them are
infected and it's dead tissue.
But the other problem could befrom an extraction from years
ago that left an unresolvedinfection and now you've got a
cavitation underneath thatextracted tooth, so it could be
cavitations.
A cavitation underneath thatextracted tooth, so it could be
cavitations, it could be rootcanal tooth.
(35:56):
It could be an asymptomaticinfection, an osteonecrosis
somewhere else in that tooth.
And almost without fail, if youlook at the acupuncture
meridians in the tooth chart,wherever you had the primary
tumor developed whether it'sbreast cancer, prostate cancer,
liver cancer, gi cancer it'llalways revert back to that tooth
along that meridian.
(36:17):
So all you have to do is justgo and get it extracted, find a
dentist who can use ozone gas,because you have to use a gas to
permeate the small tubules ofthe tooth and the jawbone to
kill the bacteria, and then theycan do a bone graft and regrow
that bone and make it strongenough now for an implant if you
(36:37):
need an implant for cosmeticregions.
But that's just the basics andso you know, when you get a
chance to understand thephysiology and the mechanism of
that, it makes perfect sense whyroot canal may be leading to
primary tumors and those aresolid tumors.
And so there's a differencebetween metastatic solid tumors
(36:57):
and bloodborne cancers likeleukemia, lymphoma, multiple
myeloma.
From my experience again, I'mnot an oncologist, I'm not a
cancer doctor, I'm a biochemistand physiologist.
But I've seen enough of thesecases to know that those are
caused from exposure to somechemical toxicant.
It's either mold and mycotoxins, it's exposure to things like
(37:17):
Roundup, glyphosate, herbicides,pesticides.
You've seen the class actionlawsuits now.
You've exposed to glyphosate orRoundup and you've developed
lymphoma leukemia.
You can get some money.
So a clear association andcausation by those.
So those are basically the boxwe have to check.
If you have a solid tumor, Isend you to a dentist, do a 3D
(37:39):
CD comb beam and then go to adentist who can extract the two,
clean up the infection and nowwe've got to get your body back
strong again, to where youcreate an environment where the
cancer cells can't grow.
But sometimes it's too latebecause unfortunately a lot of
the people that contact me havegone through chemo radiation
surgery and they're sent home todie on hospice and I can't
(38:03):
always rescue those patientsbecause they've been poisoned,
they've been radiated andthey've never addressed the
underlying root cause of theircancer and every disease process
reaches a point where there's apoint of no return.
So what we're trying to do isget this word out there and this
has been known for 60 years.
All you have to do is look forit.
(38:24):
But people would never in theirright mind again.
I taught in medical schools,I've talked to a lot of dentists
and this is never taught.
So if you don't know what tolook for, you're not going to
find it.
But if you know what to lookfor, there's a preponderance of
evidence out there dating back50, 60 years on the association
with dental infections, rootcanals and primary tumor
(38:46):
formation.
Speaker 2 (38:48):
You know you stated something about Ayurveda
medicine.
I'm a big, huge fan of Ayurvedamedicine and every organ in
your body is such an essential,every single organ is so
important.
Yet in today's world, themedical industry, we're so quick
to remove gallbladders and thisand that, and so I mean, how
(39:10):
effective is that?
I mean, are we shortening lifeby doing that?
Because I think gallbladder issuch an important?
But every other person that haspain there is just, you know,
cut off, remove.
Everything is just remove,remove, remove.
We're not really looking at allthese other you know research
and evidence.
Speaker 1 (39:31):
Well, when you're a hammer, everything looks like a
nail.
When you're a surgeon, you knowthey want to remove things and
they want to do surgery.
And if you've got an afflictingorgan, rather than try to
understand what's causing theaffliction, they just want to
take it out.
And for me, I believe that mycreator didn't make any mistakes
and I'm going to leave herewith what I can't do.
Speaker 2 (39:51):
That's right.
Speaker 1 (39:53):
Look, it's all connected because you go back to
how does the gallbladder work?
What causes the gallbladder tobecome clogged and gallstones
and dysfunction, it's thatsecretion and the recognition of
that acid load from the stomachand all that enters into the
portal at the same level as thepancreas, the liver, the
(40:14):
gallbladder, and so if you'renot getting that, the
gallbladder never gets thesignal.
Hey, I need to secrete a littlebile here to break down these
fats and so it becomes cloggedand then they take your
gallbladder out.
Now you can't digest fats, youcan't absorb basic nutrients and
it's a life of misery.
Because they're quick to react,they just want to take it out
(40:35):
and eliminate the symptoms.
But you haven't addressed theroot cause of why they had the
symptoms in the first place.
Speaker 2 (40:39):
That's right, dr Bryan.
What are the best ways fromyour perspective?
A person can increase bloodflow in the body, since that's
such an essential.
Speaker 1 (40:50):
Well, there are a number of vasoactive substances
in the body right.
There's vasodilators andthere's vasoconstrictors, and so
what we have to do is maintaina balance of both of those.
But nitric oxide is the mainvasodilator.
So if you can't, if you losethe ability to produce nitric
oxide now, you've lost thevasomotor activity and the
response to vascular reactivity.
So we just have to prevent theage-related decline of nitric
(41:12):
oxide production.
We've got to maintain a healthyoral microbiome, We've got to
eat nitrogen-rich foods and wehave to provide the body the
nutrients it needs.
And for the enzyme to makenitric oxide, it requires eight
different cofactors andsubstrates, one of those being
magnesium, and 75% of Americansare deficient in magnesium,
based on the government's owndata and I'm not a big believer
(41:35):
in government data, but you knowthat's real data and so 75% of.
Americans are deficient inmagnesium, the basic nutrient we
need for 800 biochemicalreactions and one of those is to
make nitroxyl.
So we focus on two things Dobasic micronutrient analysis,
understand what your body'smissing and then supplement it
(41:56):
back.
And then, number two,understand what your body's
exposed to.
What toxins are there presentin your body that's inhibiting
basic biochemical reactions?
Because people get sick for tworeasons, and two reasons only
they're missing something theyneed or they're exposed to
something that's toxic.
And if you address those twofundamentals, which is very
basic detoxify, replete missingnutrients, then the body heals
(42:20):
itself and the body basicallydoes what it's designed to do to
repair and replacedysfunctional tissues.
And we're regenerative bynature, the human body is
regenerative by nature.
And eliminate drug therapy andsynthetic compounds and pay
attention to what you put in andon your body.
Speaker 2 (42:38):
That's right If a person is diagnosed with cancer.
Dr Brian, what are the?
What are?
The first thing, what's thefirst thing on second and third
that they should do?
Speaker 1 (42:49):
second and third that they should do.
First, if it's a solid tumor,you know a primary tumor, or
even if it's, you know, advancedand it's metastatic disease and
they got, you know, cancer allover their body, the first thing
is go see a biological dentist.
And when I say go see abiological dentist, this isn't
your local dentist in your townor in your community.
You have to.
(43:11):
There's an organization calledInternational Association of
Biological Dental Medicine,iabdm.
And the website is iabdmorg andyou can put your zip code in
there and it'll give you a localbiological dentist in your area
that's familiar with this typeof dental and systemic medicine.
Then there's another reallygood dental group called IAOMT.
(43:33):
It's the InternationalAssociation of Mercury Toxicity,
IAOMT IOMT.
Speaker 2 (43:38):
IAOMT, i-a-o International.
Speaker 1 (43:44):
Association of Oral Medicine and Toxicology, and
then the other is theIntegrative Dental.
Speaker 2 (43:51):
Medical Society.
Speaker 1 (43:52):
And that's a really good group.
And these are the dentists thatare on the forefront of dental
medicine and who understand theroot cause in this oral systemic
link and know how to mitigateand remediate the infections the
dental infections where thenormal dentist is trained in.
today's dental schools don'tunderstand this at all, and so
(44:12):
that's what I do, then the otherthing is, you know, especially
if you've undergone chemotherapyand radiation, we have to
detoxify you.
That's right, because you'vebeen exposed to some really,
really toxic chemicals andradiation.
And we can put people in sauna,we can give them chelators, you
know, high-dose niacin and then, give them binders to.
(44:33):
If they mobilize the toxins,they need to excrete them.
But our main routes ofexcretion of toxins are
breathing.
We have to learn how to deepbreathe and take deep breaths.
We have to sweat.
That's one of the benefits ofsauna.
We have to stay hydrated withgood, clean, fluoride-free water
, and then we have to haveregular bowel movements.
So if we're not drinking a lotand if we're not urinating a lot
(44:55):
and not pooping and sweatingand doing deep breathing, we get
a buildup of toxins.
Speaker 2 (45:00):
And that's cheap right, that's costly.
These are just normalbiological responses, that's
right, we just have to look outfor what about fasting?
Yeah, how effective is fasting.
Speaker 1 (45:13):
Look again.
Everything I do is based onwhat's published in the
scientific and medicalliterature and there's enormous
benefit from intermittentfasting.
Caloric restriction is probablythe most powerful thing you can
do to improve longevity Caloricrestriction.
Caloric restriction Caloric yeah, so eating less calories.
You know, everything in the USis based on a 2,000-calorie diet
(45:34):
and everybody's different,right?
If you're a well-trainedathlete and you're competing in
the Olympics, you need toconsume a lot of calories to
fuel you during your event.
But if you're the normal couchpotato American, then you don't
need to eat a whole lot ofcalories because you're not
burning them and what happens isyou're going to store this fat.
But I do an 18-hour fasttypically every day.
(45:57):
This is sometimes difficult whenI'm traveling in different time
zones, but I think what isclear is that when you do the
intermittent fasting and you gofor these prolonged periods, it
completely rewires yourmetabolism and upregulates these
longevity genes and inducesmitochondrial biogenesis and
improves mitochondrial ATPproduction and it clears out
(46:17):
these what we call zombie cells.
And so you have these old cellsthat aren't functioning and we
have a process called autophagy.
It's called self-eating.
When we do intermittent fasting, or even 24-72 fasting,
autophagy is turned on and westart eating up these old
dysfunctional cells and wegenerate nitric oxide and we
(46:39):
mobilize stem cells and wereplace those old zombie cells
of senescent cells with cellsthat actually function.
Speaker 2 (46:45):
My father is big on that.
Speaker 1 (46:47):
Yeah, no, look, it's been life changing for me
because I, you know, we weretold you know, breakfast is your
most important meal of the day.
You have to eat breakfast.
But I mean, we've beenmisinformed so much by the
so-called policy makers that Idon't believe anything they say
anymore.
Speaker 2 (47:04):
That's right.
Question authority.
Speaker 1 (47:06):
Yeah, absolutely.
Speaker 2 (47:07):
Yeah, what should people look for when considering
nitric oxide supplements?
Speaker 1 (47:14):
Yeah, look, that's a loaded question and it's
confusing.
You know, I've been doing thisfor almost 30 years and I'm
pretty well informed and I goand look and see what's online.
If you just Google nitric oxidesupplements, you're going to
get a laundry list of all these,and so it's what comes up.
First are the companies who paythe most money.
First are the companies who paythe most money, and mostly
(47:36):
these companies who pay the mostmoney are spending more money
on marketing and no money onscience and understanding the
underlying problem of why peopleare nitric oxide deficient.
So about 95, 99% of theproducts on the market that are
sold as nitric oxide productsare placebos in terms of nitric
oxide.
Wow.
So, and the reason is that thesecompanies don't understand the
(47:56):
underlying biochemistry and thecomplexity of the science.
They just read our article andgo oh well, l-arginine is how
you make nitric oxide, so youget all these products with
L-arginine or L-citrulline.
And then beets came up.
You know, a hero vegetable inthe 2012 Olympic Games.
So people are selling beetrootproducts and beetroot powder and
(48:17):
things like that, and I'vetested all these and they're
basically placebos.
That's right.
All they do is turn your pee andyour poop red and cause a lot
of anxiety.
People think they're having adream.
That's hilarious.
I can't tell you how many callsI've gotten from that.
What I've tried to do over thepast 15 years is how does the
consumer know?
(48:37):
Because, based on the DietarySupplement, health and Education
Act, what we called the SHEAback in the 90s every supplement
manufacturer basically can saythe same thing May support
healthy blood pressure, sexualfunction it's called structure
function claims.
So all these companies,including myself and my
companies, we can't make drugclaims because we're supplements
(48:59):
.
So how do you identify aproduct that actually works?
And so supplements fall in thecategory of nutraceuticals right
Nutrients that supplement orprovide therapy.
Soutical means therapy.
So I trademarked a term which Icalled nitroceuticals.
It's nitric for nitric oxide,and so all of my products are
(49:22):
nitroceuticals because itproduces nitric oxide and we can
quantify, we can detect, we canverify nitric oxide gas coming
off my products and they'renitroceuticals, they aren't
nitroceuticals, they'renitroceuticals, they aren't.
They aren't nitroceuticals,they're nitroceuticals.
And so I encourage people lookfor, look for products that
actually produce nitric oxidegas.
(49:43):
So if your body can't make it,then I'm going to do it for you,
and this is hormone replacementtherapy at its very best, if
you're.
If men can't make testosterone,what do we do?
We give them testosterone.
We don't give them DHEA andhope their body can make
testosterone out of it.
We don't give them HGH and hopetheir body stimulates
testosterone.
That's their problem they can't.
They've lost the ability to doit.
(50:04):
And it's the same thing withnitric oxide.
The reason people are nitricoxide deficient is they can't
utilize arginine.
They don't have the right oralbacteria to convert any nitrate
and beet juice into nitric oxide.
You can't make stomach acid tomake nitric oxide, so no matter
what you give them, they can'tmake it.
So that's what we do.
That's different is, if yourbody can't make it, then we do
(50:27):
it for you and but we also fixthe reason your body can't make
it.
Spending 20 years working onthese enzymes that make nitric
oxide, I know how to restore thefunction, so we put that in our
technology and we're restoringthe oral microbiome.
Speaker 2 (50:41):
That's amazing, Dr Bryan.
We've talked about the adultsbriefly.
I know we're almost out of time.
I want to talk about thechildren Now.
I have a two-year-old and a10-year-old.
How can mothers and the fathersand the families that are
watching maintain the health andthe nitric oxide of their
children?
What are some things that wecan do to, you know, keep them
(51:01):
healthy.
Speaker 1 (51:03):
Well, it starts at conception.
You know the mother and thefather have to have good
nutrients.
So you've got a viable cell,viable sperm, and then,
especially the mother, duringthose nine months of gestation,
you have to have good nutrition,limit your exposure to toxins,
so you're creating anenvironment for that baby to
grow and thrive and haveeverything it needs.
And then, upon birth, you knowwe need to breastfeed.
(51:25):
There's clear healthdisparities between breastfed
and formula fed babies.
So and I understand, there'scertain times when women can't
breastfeed, their milk doesn'tcome in or other reasons Most
important thing, give the babygood nutrition, but
breastfeeding, it's nature'smost perfect food, god give it
and then you know when theystart eating solid foods.
You know, certainly do not giveantacids to a baby, even though
(51:48):
they may be prone to spitting upand regurgitating at times.
But avoid antacids and just youknow again.
Good, high quality foods, notprocessed foods, good fats, lots
of protein.
You know baby's metabolicdemands as they're growing may
need a little bit more carbsthan kind of a full grown adult,
because they're reallymetabolically much more active.
(52:10):
But, yes, basic good nutrients,elimination of toxins and
physical activity love that andavoiding fluoride avoiding.
Now there's data I think there's40.
There's a meta-analysisrecently produced showing, I
think, 40 independent studiesshowing that fluoride lowers the
iq in kids that's right.
(52:30):
I mean you've got it.
This is awful, and I think,with this new administration and
an rfk going in there, you knowwe're going to start
eliminating fluoride in ourmunicipal water and you know, I
spoke before the American DentalAssociation last summer and I
think we're finally getting theattention of the ADA.
And so just because you didthis 100 years ago doesn't mean
it's still sound science today.
We can do better.
Speaker 2 (52:52):
Yeah, I have been rejecting that since my eldest
was born.
He's 11.
And I kid you, not 11 years ago, when you said no fluoride to
the dentist, oof.
Speaker 1 (53:02):
It kicked you out, right.
Speaker 2 (53:03):
Yeah, it did.
I was looked at as a crazy madwoman, but you know.
Speaker 1 (53:08):
God told me, your intuition that's right, that's
right, dr Bryan.
Speaker 2 (53:14):
It's been such an honor.
Thank you so much.
The information is amazing.
I've learned so much from you,as the audience have, and I
appreciate you.
I'll link everything so thateverybody knows where you are
and how they can definitelyreach you, because you're such
an important person.
You're like God given.
This is God's work, becauseyou're such an important person.
Speaker 1 (53:34):
You're like God, given this is God's work, I feel
we have an obligation andresponsibility to get, because
it's education and it'sknowledge, and you know,
knowledge is power, but only ifyou, if you act on it, and so
there's a lot of misinformationout there and let me just plug
my upcoming book.
I got a new book coming out herein a couple of weeks called the
Secret of Nitric Oxide andreally in that book I tell, I
chronicle what nitric oxide is,how it was discovered, what
(53:56):
we've learned, and really talkabout kind of the part
autobiographical of thediscoveries we've made and how
we've got to where we are today.
But the purpose of the book isto empower the reader to
understand these things thatthey may not have even
considered and to take actionand do these simple things and
to maintain optimal nitric oxideproduction and you'll see their
(54:16):
life transform.
Speaker 2 (54:19):
That's right.
And before we go, there's thisone question that I ask all the
professionals on my show, andit's going to ask you this
question If there was onesupplement that you would take
and give it to your children,what would that one supplement
be?
Speaker 1 (54:37):
Well, look, you're asking a strong person.
Speaker 2 (54:41):
I'm saying magnesium, but I would love to know your
perspective.
Speaker 1 (54:47):
Well, no, I mean based on just the work.
If I'm limited to one, I wantto enhance my nitric oxide.
So I would take my N1O1 lozengebecause it contains magnesium.
It produces nitric oxide, andwhen you have adequate blood
flow, adequate tissueoxygenation, adequate
mitochondrial function, lowerinflammation, no oxidative
stress or immune dysfunction,then the body can function.
(55:09):
And so that's what I take.
That's what I've been takingnow for more than 20 years, even
some early prototypes of it,but it's our nitric oxide
generating lozenge.
Speaker 2 (55:18):
That's your brand.
Speaker 1 (55:19):
That's my brand N101.
Speaker 2 (55:21):
Okay, and if you weren't limited to one?
Speaker 1 (55:26):
The next would be iodine.
There are 12.5 milligrams ofiodine a day because the
American diet is completelydepleted of any iodine.
95% of Americans are deficientin iodine.
There's iodine receptors onevery cell.
You need iodine to make stomachacid in the palloric cells.
You need stomach acid toconvert thyroid T4 to the rise
of autoimmune disease my goshPart of our immune dysfunction.
(55:49):
Iodine is antibacterial, so ifyou develop iodine deficiency,
then bad things are going tohappen.
So I think that's a veryimportant, very neat nutrient.
But those are my go-tos.
Speaker 2 (56:01):
Awesome.
Well, thank you so much.
I appreciate you and you have ablessed day.
Speaker 1 (56:06):
Thank you very much.
Same to you.
You can't do it to the heart, you can't do it to
the brain, the liver, the lungs,every organ in the body.
And then, number two, you startto see an increase in blood
pressure and because nitricoxide is a vasodilator, it's
opening up the blood vessels.
So now you're.
If you lose the ability to makenitric oxide, you become
chronically constricted.
Now you've got the same volumeof blood going through smaller
(00:22):
pipes, if you will, and thatcauses an increase in blood
pressure.
Speaker 2 (00:26):
Basic physics Hello everyone, thank you for joining
me today.
I took a long break, but it'swonderful to be back.
This episode I want to presentto you in such an eloquent way.
(00:48):
He is world-renowned researcher, dr Nathan Bryan, somebody
that's dear to me, an incrediblyessential human being.
Dr Bryan is doing God's workand he has helped so many people
understand the essentialimportance of nitric oxide.
He's recently released a book,the Secrets of Nitric Oxide, and
(01:13):
on this show today we're goingto dive right into it and how
important it is to live and Imean that to live.
It's such an important asset ofour body and he's going to
explain to us what nitric oxideis, why we're deficient in it,
how do we know if we'redeficient and, if we are, what
are the causes, what are thesymptoms and how can we get it
(01:34):
back.
So thank you for joining me andI'm very excited to show Dr
Nathan Bryan, phd on nitricoxide.
All right, dr Brian, it's sonice to have you on my podcast.
It's an honor.
I love your work, I follow yourwork and I appreciate you, and
I'm very, very grateful that youaccepted my invitation.
(01:57):
So thank you.
Speaker 1 (01:59):
Thank you, those are kind words and I appreciate this
and honor and invite for the.
You may invite me to be withyou, so I'm looking forward to
it.
Speaker 2 (02:07):
Absolutely All right, let's get into this amazing
conversation of nitric oxide.
So how did you get into thisfield?
You have a PhD.
You've been studying this formany, many years and have worked
with hundreds and hundreds ofpatients.
So tell us what is nitric oxide?
Speaker 1 (02:26):
Well, you know it's a fascinating molecule.
It's a gas that's naturallyproduced in the body.
The odor we get, the less wemake, and that's what's
responsible for age-relateddisease.
But I was first introduced tothe science of nitric oxide in
the late 90s, early 2000s, whenI was a student at LSU School of
Medicine.
They were working on a PhD inmolecular and cellular
physiology and a Nobel Prize hadjust been awarded in 1998 for
(02:50):
the discovery of nitric oxide.
So you know it was an excitingtime.
Everybody had a lot of promisefor this molecule, that it had
really the potential to changethe world, of managing chronic
disease, even preventing a lotof the poorly managed chronic
disease that we're still dealingwith today.
And so that's how I gotintroduced to this.
And you know, fast forward 30years, 25 years Now, here we are
(03:15):
.
We've made a lot of discoveries.
So there's over 200,000scientific papers published in
the nitric oxide literature.
So you know we understand a lotmore today about nitric oxide
certainly than we did 25 yearsago.
Speaker 2 (03:24):
So when you say that as you get older, that your body
produces less nitric oxide,from what age are we looking at?
Speaker 1 (03:36):
We know it's quite variable and so let me just
preface that by saying there'sreally two ways the body makes
nitric oxide.
There's an enzyme in the liningof the blood vessel and when we
talk about this age-relateddecline in nitric oxide
production, it's really lookingat the function of the enzyme
that typically makes nitricoxide from L-arginine.
That's called the NOS pathwayand so it's similar to.
(03:59):
You know you can kind of mirrorthe effects we see in human
growth hormone.
You know it peaks kind of inour teens and then just steadily
declines as we get older.
But there are many things thatcontribute to a loss of nitric
oxide production in terms of thefunction of that enzyme.
But today we know that we don'tnecessarily see that age-related
(04:20):
decline.
We can prevent it, we canprolong it or we can accelerate
it.
Related decline we can preventit, we can prolong it or we can
accelerate it.
So to answer your question, youknow today there are 18, 20, 24
year old kids and young peoplethat have the nitric oxide
production of a 60 or 70 yearold and we have people like, for
instance, I'm 51, and I havethe kind of the nitric oxide
(04:40):
production potential of someonein their 30s production
potential of someone in their30s.
So we can you know it's not astatic kind of concept, but it
depends upon diet, it dependsupon lifestyle, it depends upon
what you put in your body, onyour body and how you really go
about every day, but it's theWestern lifestyle diet, physical
inactivity, pharmaceuticaldrugs, antacids, fluoride,
(05:03):
antiseptic mouthwash,antibiotics all of those lead to
a loss of nitric oxide or anaccelerated decrease in nitric
oxide production.
Speaker 2 (05:12):
Now I want to ask these two questions.
You said food has an impact onnitric oxide, so does this mean
that whether you eat organicfood or grass-fed meat, do all
of these play a factor in thedecrease of nitric oxide?
Speaker 1 (05:31):
They do.
And so what we're finding isthat diet really serves two
functions.
Number one you've got toeliminate things in your diet
that are inhibiting nitric oxideproduction, and then you've got
to start including things inyour diet that can enhance or
stimulate and activate nitricoxide production.
So then you got to startincluding things in your diet
that can enhance or stimulateand activate nitric oxide
production.
So really, the biggest culpritin inhibition of nitric oxide is
(05:51):
sugar.
So you know, we we wereconsuming way too much sugar in
the Western world and simplecarbohydrates.
So simple, elimination of sugar.
You know, we explained thisbecause sugars, or glucose, is
like glue right, it's the rootword of glucose.
It's a glue, it sticks thingstogether.
So when you have an elevationin fasting or blood glucose
(06:14):
levels, that molecule, thatsugar, sticks to things like
hemoglobin, and we measure thatas hemoglobin A1C.
But it also sticks to enzymes,and enzymes in biochemistry and
enzymology are designed toundergo conformational change to
transfer electrons throughdifferent domains of an enzyme,
and if there's too much sugar onthere, it's stuck in a single
conformation so that enzymecan't do its job.
(06:37):
So that's number one you have toeliminate sugar,
sugar-containing supplements,sugar-containing foods and then
start to increase theconsumption of green leafy
vegetables, healthy fats, a lotof protein.
Now, you know, the older we getthem, the higher consumption of
protein that's required toprevent muscle loss and bone
loss.
So those are the biggies.
(06:58):
And I'm not a big fan ofhardcore vegan, hardcore
carnivore, keto.
But I think the most importantthing is eliminate carbs and
sugar and then, you know, eat abalanced diet in moderation Lots
of protein, good fats, verylittle carbs.
Speaker 2 (07:14):
What are some of the symptoms a person can experience
if their nitric oxide isdecreasing?
Speaker 1 (07:20):
Yeah, you know, we've come a long way in
understanding that, and that's areally important question
because it's not part of yourstandard lab.
So if you go to your physicianor healthcare practitioner and
they want to draw blood, thereis no option.
For what is my nitric oxidelevels?
Right, because it's a gas.
Once it's produced, it's gonein less than a second.
So we have to rely on symptomsand the presentation of symptoms
(07:42):
in people.
So usually the first thing thatyou see and experience when your
body has the inability toproduce sufficient nitric oxide
is sexual dysfunction orerectile dysfunction.
That occurs in both men andwomen, because in order for
women to have an orgasm or mento have an erection, we have to
dilate the blood vessels of thesex organs, and that's done
(08:02):
through the production of nitricoxide.
So if we've lost the ability toproduce nitric oxide, we don't
get dilation, we don't getencouragement, women become an
orgasmic and men can't get anerection.
So that's number one and that'swhat we call the canary in the
coal mine, because if you can'tproduce nitric oxide and
regulate blood flow to the sexorgans, you can't do it to the
heart.
You can't do it to the heart,you can't do it to the brain,
(08:22):
the liver, the lungs, everyorgan in the body.
And then, number two, you startto see an increase in blood
pressure.
And because nitric oxide is avasodilator, it's opening up the
blood vessels.
So now you're.
If you lose the ability to makenitric oxide, you become
chronically constricted.
Now you've got the same volumeof blood going through smaller
(08:42):
pipes, if you will and thatcauses an increase in blood
pressure.
Basic physics so, an increase in.
Two out of three Americans havean unsafe elevation in blood
pressure.
So that should tell you howmany people are nitric oxide
deficient.
And then, number three, youstart to get metabolic disease,
things like glucose and insulinresistance, type two diabetes,
(09:04):
because in order for insulin towork in the cell and for that
cell to bring in glucose andclear it from the circulation,
it requires that cell to be ableto produce nitric oxide.
The nitric oxide is part of theinsulin signaling pathway and
responsible for glucose uptake.
And then, number four, youstart to develop exercise and
tolerance.
If you can't walk up a flightof steps or do basic exercise
(09:26):
without becoming windedtightness of chest, then your
body can't make nitric oxide.
And then, fifth, you start toget dementia and.
Alzheimer's.
We and others have discoveredthat really Alzheimer's disease
is a symptom of nitric oxidedeficiency.
It's lack of cerebral bloodflow, it's insulin resistance,
it's type three diabetes, andnitric oxide corrects all of
(09:48):
those.
So if you maintain normalperfusion, you don't get the
focal ischemia, you can maintainnormal glucose uptake in the
brain.
You don't get misfolding ofproteins.
So there's no taut angles,there's no amyloid plaque built
up and all that can be correctedby maintaining optimal nitric
oxide levels.
Amyloid plaque built up.
Speaker 2 (10:05):
And all that can be corrected by maintaining optimal
nitric oxide levels.
Exactly and what I noticed.
Now I want to get into theproton pump inhibitors.
I want to talk about that?
Yeah, because some of thesymptoms that you just described
that occur from decreasing thenitric oxide.
Do they prescribe these protonpump inhibitors to help with the
situation?
Look, I've never understoodthis type of drugs.
Speaker 1 (10:31):
Now look the standard of care in Western medicine and
I think it's kind of gone allover now but if you're admitted
to the hospital, and it doesn'tmatter if it's from trauma or
influenza-like illness or moreserious critical conditions such
as a heart attack or stroke.
And it doesn't matter if it'sfrom trauma or influenza-like
illness or more serious criticalconditions such as a heart
attack or stroke.
The first thing they do is giveyou omeprazole.
Speaker 2 (10:51):
Yes.
Speaker 1 (10:52):
Prilosec and proton pump inhibitors, and so to me
it's no wonder that people getworse when they're admitted into
a hospital and very few peopleget better, because if you've
ever been to the hospital andeaten hospital food.
It's I mean it's.
It's criminal.
But even more criminal isgiving these patients proton
(11:13):
pump inhibitors without any realindication, and these are only
approved for gastroesophagealreflux disease.
But here's what happens If youput patients on a PPI they can't
absorb nutrients things likemagnesium, iron, selenium,
chromium, iodine, b vitamins andyou can't break down proteins
into amino acids.
So you start to developfoodborne allergies and you
(11:35):
can't regulate acid base balanceand you become acidotic.
We saw this in COVID from thehypoxemia and the acidosis from
admitted COVID patients.
So giving PPIs is the worstidea in the world that I could
think of as a biochemist andphysiologist.
But you would only give them ifyou wanted to make your
patients sicker.
So there's a host of bad thingsthat happen with inhibiting
(12:00):
stomach acid production.
I mean, secretion of stomachacid is probably one of the most
fundamental critical aspectsabout human physiology.
But it's also these drugs arecompletely in shutting down
nitric oxide production andagain we like to start with
important clinical observationsand then work back to figure out
mechanism.
But if you just look at theclinical data and these drugs,
(12:22):
have been on the market fordecades now, and it was clear
that if you've been on a protonpump inhibitor and these drugs
have been on the market fordecades now and it was clear
that if you've been on a protonpump inhibitor and these are
things like Prilosec, prevacid,nexium, omeprazole, pantoprazole
those are the prescriptionmedications Now you can get them
over the counter.
If you've been on those drugsfor three to five years, what
the clinical data tell us isthat you have a 40% higher
(12:43):
incidence of heart attack,stroke and Alzheimer's.
Speaker 2 (12:46):
Alzheimer's Right.
I was reading your yeah, yeah.
Speaker 1 (12:49):
So yeah, I mean, we have to do better, we can do
better.
And it's just.
The data are very clear.
Now we just have to apply thepressures.
You know these drugs shouldhave black box warnings on them
because they're dangerous andthey should be taken off the
market.
I think these drugs are moredangerous, more deadly, than the
COX-2 inhibitors from the early2000s that were killing people
(13:11):
left and right from heart attackand stroke and taken off the
market for a brief time.
But now they're back on themarket with a clear black box
warning that these drugs cancause heart attack and stroke,
and the same thing should beacknowledged for proton pump
inhibitors.
Speaker 2 (13:32):
I was watching a few of your podcasts and one thing
that you had said is, I think,that we're afraid of acid in our
body.
We try to contain that as muchas possible, but, understanding
your work, what you're sayingit's needed Because if we don't
have it, then our supplementsare like magnesium and so are
not going to be breaking downproperly in our body.
Can you explain us?
You know a little bit aboutthat.
(13:53):
Yes, so the gastrointestinalsystem.
Speaker 1 (13:55):
First of all, the human body is a lot smarter than
we are.
It knows what to do under allcircumstances.
We just got to get out of theway.
So here's how normalgastrointestinal physiology is
designed to work.
When we eat food, we getnutrients from our food.
This is the basic parts ofenergetic and converting food we
eat into cellular energy.
(14:15):
We need stomach acid to absorbthings like B vitamins,
magnesium, selenium, iron,chromium, iodine.
So if we can't make stomachacid, then when we consume these
foods that contain thesenutrients, they just pass right
through.
You know, the gi tract from themouth to the anus is the outside
world.
I mean, it's a hollow type thatgoes hollow pipe that goes
(14:38):
straight through us.
It's the outside world.
Yeah, so our gi system, ourepithelial cells, our gastric
mucosa and the lumen of thestomach, those different
environments are designed toabsorb specific nutrients.
Along passage from the stomachto the duodenum, the jejunum,
small intestine, largeintestines, colon At different
stages of digestion, there'stransporters that take up
(15:01):
nutrients from the food and thenput it inside our body so that
our cells can use it.
So that's number one.
Number two is that for thepancreas, the exocrine pancreas,
to secrete sodium bicarb, whichis the buffer system to make
sure that our body maintains anormal pH of 7.4 and an
electrical potential of minus 25millivolts across the cell
(15:22):
membrane.
we have to secrete sodium bicarbfrom the pancreas, and the
signal to tell the pancreas tosecrete sodium bicarbonate is
the acid dump from the lumen ofthe stomach.
So if our body's not makingstomach acid, the duodenum, the
early part of the smallintestine, doesn't detect and
get the signal.
Hey, I need to secrete somesodium bicarb and that's the
(15:44):
acid-based buffering and theacid-based system for
maintaining normal cellularpotential voltage and pH.
So this leads to a hallmark ofa number of problems.
And then the other thing isthat you can't break proteins
into amino acids.
So you know, we make humanproteins.
We're never designed to take onanimal proteins or plant
(16:06):
proteins.
Speaker 2 (16:07):
Really.
Speaker 1 (16:08):
Proteins are made up of amino acids.
Right, so when we consume plantprotein or animal protein, the
purpose of the stomach and itsacidity is to activate an enzyme
called trypsin, which thencleaves that peptide bond and
releases amino acids.
So now the amino acids can beabsorbed in the small intestines
(16:30):
and then we transport thoseinto the cell and we make human
proteins out of those basicamino acids.
But if you don't have stomachacid, you can't break those down
.
Now you have peptide fragmentsthat are absorbed across the gut
.
You lose the integrity of thebarrier, the epithelial cells,
and now your body sees this as aforeign substance and it makes
antibodies against it because itdoesn't recognize foreign
(16:53):
proteins or foreign peptidefragments.
And for me that's the basis ofall foodborne allergies.
You know, when I was a kid inschool we didn't have kids with
peanut allergies, milk allergies, all these allergies.
And because I think it's whenkids throw up or spit up as a
baby, what do you do?
The pediatrician gives them anantacid and now that makes them
(17:13):
prone to foodborne allergies,because they can't break down
milk proteins, they can't breakdown proteins like gluten and
peptides, so they developintolerance to them and
foodborne allergies are born.
So nitric oxide is important,obviously for a number of
reasons, but we have to get awayfrom inhibiting stomach acid
production.
(17:34):
I think it's what's leading tomost of the symptoms and
syndromes and things today.
Speaker 2 (17:39):
My goodness, dr Bryan , can we get into the four
hallmarks of disease?
I think this is such animportant matter to kind of
address If you briefly explainto us what they are so we can
understand them better.
Speaker 1 (17:55):
Well, you have to kind of take a step back and
look outside of how medicine ispracticed today, because
everything is siloed right.
So if you've got a heart orvascular issue, you go to your
cardiologist and he's onlyfocused on your heart and blood
vessels.
Yes, please, neurologist, butyou got to remember everything
is connected.
And so whether you're lookingat heart disease, liver disease,
(18:27):
kidney disease, neurologicaldisease, when you step back and
look, there's always commondenominators and those four
hallmarks are low blood flow tothe organ.
So in cardiovascular disease weget a buildup of plaque in the
coronary arteries and you get anobstruction of blood flow and
we develop ischemic heartdisease In the brain, whether
it's Alzheimer's, parkinson's,adhd, bipolar, through imaging,
(18:50):
spec scans, functional MRIs, wesee that there's a loss of
regulation of blood flow to thebrain.
So number one, it's low bloodflow.
And then number two isinflammation.
We know inflammation is whatdrives chronic disease.
Number three is oxidativestress.
And then, number four, we startto develop immune dysfunction.
And so if you go back and now,mechanistically and we and
(19:10):
others have discovered for thepast 25 years if you can prevent
the age-related decline innitric oxide production, you
maintain normal perfusion of theorgan.
It inhibits inflammation.
In fact I've got a number ofissued patents that are on
(19:31):
methods of reducing inflammationby nitric oxide and we
completely inhibit the oxidativestress that occurs we see in
most disease processes and wemitigate the immune dysfunction.
So simply by giving nitricoxide or restoring the
production and signaling ofnitric oxide, you're addressing
the hallmarks of every singlechronic disease.
Speaker 2 (19:51):
I think what I have learned from reading so much
about research like howessential blood flow is in a
person's body.
Speaker 1 (19:56):
That's right.
Yeah, it's blood flow, and it'soxygenation.
So there's two things it'shypoxia, which means low oxygen,
or it's ischemia, which means adisruption in the blood supply,
whether there's oxygenatedblood or not.
So ischemia occurs when there'san obstruction, either a
thrombus or an embolism.
That's what happens in ischemicstroke or an acute MI there's
(20:17):
an occlusion of the bloodvessels.
There's no blood flow gettingin, it's a roadblock.
The other problem and weexperienced this, this during
COVID was the hypoxemia.
So you may have adequate bloodflow and circulation, but the
hemoglobin, the oxygen carryingcapacity of the red cell, is
compromised.
And again, all that iscontrolled by nitric oxide.
Nitric oxide dilates the bloodvessels to improve circulation
(20:41):
and it's how we oxygenatehemoglobin in red blood cells.
So nitric oxide controlseverything we know about
circulation and tissueoxygenation.
Speaker 2 (20:52):
Earlier we were talking about heart disease and
heart attacks.
Are those also caused by thelack of nitric oxide in the body
, like high blood pressure?
Because number one killer rightnow is heart disease and heart
attack right.
Speaker 1 (21:07):
It has been for the past 100 years.
Speaker 2 (21:09):
Yeah, so what are some things that people can do
to prevent that?
I mean, what can we do to havemore nitric or maintain our
nitric oxide?
Speaker 1 (21:19):
Well, I'll just answer the first question.
The first question is yes.
So when we lose the ability tomake nitric oxide the functional
loss of the endothelial cells,which are the cells that line
all blood vessels throughout thebody when those endothelial
cells lose the ability toproduce nitric oxide, you start
to get an upregulation ofadhesion molecules and then
monocytes, neutrophils.
(21:40):
Cholesterol starts sticking andit's transported across the
endothelium into the intima.
Cholesterol starts sticking andit's transported across the end
of the limb into the intima.
You get smooth musclehyperplasia, intima media
thickness and you start toocclude the lumen of that blood
vessel.
And then that starts theinflammation, oxidative stress
and immune dysfunction.
So that functional loss ofnitric oxide occurs years,
(22:00):
sometimes decades, beforethere's ever a significant
occlusion or stenosis of, forinstance, the corneal arteries
or the carotid arteries.
But then and the otherimportant thing about is this
nitric oxide can actuallystabilize plaque.
It can prevent the plaque fromfrom occurring in the first
place.
But it's really not the degreeof stenosis that causes the
(22:21):
problem, it's the vulnerabilityof the plaque.
Stenosis that causes theproblem.
It's the vulnerability of theplaque.
And about 50% of heart attacks,sudden cardiac death, in America
, is in patients who have lessthan 50% stenosis of the
coronary arteries.
So it's the vulnerability theygot vulnerable plaque that
erupts.
Now you've got a thrombus andan embolus that goes down, clogs
(22:41):
up those coronary arteries andthat's acute MI or myocardial
infarction, and many peopletheir first sign is sudden
cardiac death and there's nogoing back from that.
So what we have to do is wehave to maintain adequate nitric
oxide production so you don'tget plaque deposition, you don't
get plaque instability and youdon't have an eruption of that
(23:01):
plaque and causing acute MI.
So it goes back tounderstanding number one, how
the human body makes nitricoxide, and then further
understanding of what's causinga loss of the natural production
of nitric oxide.
Then, and only then, can youstart to kind of suggest or
recommend therapeutic strategiesto restore nitric oxide.
So we've touched on those alittle bit.
(23:22):
I mean you have to get rid ofantacids, you have to get rid of
antiseptic mouthwash and Maybethat's probably a nice segue
into this other pathway, becausewe discovered that the oral
bacteria are responsible forproducing nitric oxide.
So anything that destroys oralbacteria fluoride, toothpaste,
and really fluoride it's nottoothpaste, it's the fluoride in
(23:44):
the toothpaste.
Or things like Listerine, scope, antiseptic mouthwash,
chlorhexidine those kill.
When you see the commercials,it says this kills 99.99% of the
bacteria.
You should believe them,because it does, and that's not
a good thing.
By the way, we have to we, nowthat the entire microbiome
project has been mapped out andwe know that the bacteria that
(24:06):
live in and on our bodyoutnumber our human cells 10 to
1.
We need to maintain a healthymicrobiome.
We don't need to kill it, weneed to support it, and so
things like mouthwash arecompletely disrupting nitric
oxide production.
We and others have publishedthat to use mouthwash, your
blood pressure goes up, you losethe protective benefits of
exercise, and so it's just badnews.
So get rid of mouthwash,eliminate fluoride, wean off
(24:30):
antacids, and then it's justcommon sense moderate physical
exercise, 20, 30 minutes ofdirect sunlight exposure day,
and then a balanced diet, inmoderation no sugar, few carbs,
healthy fats, a lot of proteinand throw in some green leafy
vegetables.
Speaker 2 (24:50):
What about some foods ?
I mean, yes, those are going tohelp the nitric oxide, but what
are some foods that we shouldstay away?
Speaker 1 (24:54):
from yeah, the white foods, bread, dairy, anything
that leads to an increase inBread, dairy, kind of your white
foods, your high glycemic indexfoods.
Speaker 2 (25:06):
What about sourdough?
Because I have a lot of momsthat make sourdough bread from
starter, you know.
So it's an important thing forus to know.
Speaker 1 (25:15):
I think it's difficult to say because
everybody's different and itdepends upon kind of your
metabolic flexibility.
And now the beauty of thesecontinuous glucose monitors you
can monitor in real time and aslong as you don't see a rapid
increase in your blood glucoselevels, you stay away from
things that cause a spike inglucose Because, as I mentioned,
(25:36):
an elevation, a prolongedelevation in glucose leads to
vascular dysfunction, leads toloss of nitric oxide production.
So just do an experiment onyourself, get you a continuous
glucose monitor.
Eat things, monitor your bloodsugar and if you have good
insulin sensitivity, then itshouldn't lead to an increase in
blood sugar that persists andlasts for many, many hours, like
(25:58):
it does in type 2 diabetics.
So, everybody's different but Ijust respond to what I know my
body tolerates and I listen tomy body and if it's insulting
and makes me feel bad then Itypically don't eat it again.
I'm too busy to feel bad.
Speaker 2 (26:12):
So there's bread and then there's processed food.
What else?
Speaker 1 (26:16):
Yeah, I mean mainly it's sugar, your simple
carbohydrates, processed foods,like you know anything that any
food product that's notrefrigerated it can sit on a
shelf for weeks, months or years.
It's probably not good for you,right?
Because food real food willspoil over time, and you've
(26:37):
probably seen it.
You know people that buy theMcDonald's food and leave it out
on the shelf for years and itdoesn't spoil.
I mean, ants won't even eat it.
I mean, we got to look atnature, right, that's true.
If ants don't touch it, it'sprobably a pretty good
indication that it's not realfood.
And so that's the McDonald'sexperiment.
Speaker 2 (26:54):
What about oils?
Dr Bryan, what oils do yourecommend?
That's good for us.
Speaker 1 (26:59):
Yeah, certainly you got to stay away from seed oils.
I mean we need, you know, oliveoil, kind of natural oils,
avocado oil, ghee, beef tallow.
Because the seed oils we got toremember and this goes back to
basic cell biology every cell iscontained within a cell
membrane and that phospholipidbilayer is made up of fats,
(27:23):
cholesterol, triglycerides,fatty acids.
And these seed oils, theseomega-6, really affect the
membrane fluidity and now welose the control of what's going
on outside and inside becausethere has to be intracellular
signaling.
The outside of the cell gets asignal and there's this seven
transmembrane signalingmechanism that depends upon cell
(27:45):
membrane fluidity.
And if we lose that, we losethe intracellular signaling
inside the cell and cells becomedysfunctional.
We develop disease and thehalf-life of these seed oils
canola oil, corn oil, vegetableoil is about 600 days, almost
two years, and what that meansis if you consume a seed oil, it
(28:06):
takes about two years for halfof it to be excreted out of your
body.
Speaker 2 (28:10):
Oh, my goodness.
Speaker 1 (28:11):
And really we need about five half-lives to
completely eliminate somethingfrom the body.
So seed oils stay around forabout 10 years and they're
causing damage, they're causingdiabetes, they're mitochondrial
toxicants, they're losing thebody's ability to communicate
cells in the body to communicatewith one another.
So we have to avoid those cellsin the body to communicate with
(28:33):
one another, so we have toavoid this.
Speaker 2 (28:34):
Dr Bryan, there has been such a high rise in cancer
rates among men and women intheir 20s, in their 30s.
I watched a recent podcast ofyours when you were talking
about you have treated hundredsand hundreds of patients and
every single one of them had ayou know something going on,
(28:55):
like whether that's I don't knowa cavity or root canal.
So can you, can you brieflytalk to us about that?
Like is, is cancer or havingproblems orally?
Is it related?
How does that relate to cancer?
yeah, it's a confusing thing,but you know.
Speaker 1 (29:13):
Yeah, you can see that that one little clip on
Instagram has hundreds ofthousands of comments and shares
and you know some really somepretty bitter and nasty
responses that you know I'vekind of fallen off the wagon and
I don't know what I'm doing.
But no, that means you're,you're making an impact because
this is thinking.
It's a completely new paradigm.
(29:34):
So, number one, I'm not aphysician.
I don't treat patients, butwhat I do is, you know, people
call me, people that are sickand chronically ill, that the
standard of care and theconventional medicine has failed
them, and so people come see meand I just give them what I
know about human physiology andbiochemistry.
But when these people, thesechronic patients that are sent
(29:55):
home to die, they've gonethrough surgery, chemo,
radiation, the standardtreatment of cancer, and even MD
Anderson will tell you they'venever cured a person of cancer
their goal is to make you diewith cancer and not make you die
from cancer.
Speaker 2 (30:13):
I mean, what a low bar right, there's a word that I
had a water scientist.
He said if the disease won'tkill you the cure will kill you.
Speaker 1 (30:28):
No, that's exactly what happens in oncology today,
and it should be criminal.
And here's the problem In everyoncologist and I've gone to the
oncologist appointments withmany of these patients that I've
developed a oncologist, andI've gone to the oncologist
appointments with many of thesepatients that I've developed a
friendship with and I simply goin and ask the tough questions
that the family obviously isn'taware of or educated enough to
ask important questions.
And I go what caused thispatient's cancer?
And no one can answer that.
(30:49):
And so my question is how inthe hell are you going to treat
something if you don't know whatcaused it?
And so every cancer is looked atthe same, but we're going to
cut it out, we're going toradiate the shit out of it.
Which radiation causes cancerin the first place?
You're going to get a toxicchemotherapeutic agent that's
going to kill all rapidlydividing cells, including those
of the gut, including those ofthe hair follicles, and we're
(31:10):
going to make you extremely sickand actually make you want to
die.
That's what I've witnessed.
People get cancer treatment.
They want to die because thelife they're living, the quality
of life, is awful, and thosethat believe you know they're
going to go on to an everlastinglife, so what we have to do is
what again look at the clinicalhallmarks of cancer and Otto
(31:32):
Warburg, in the 1920s and 30s,discovered that cancer is a
metabolic disease and he wasawarded a Nobel Prize.
It's called the Warburg effectbecause cancer cells only thrive
, replicate, proliferate in alow oxygen, low pH environment
through mitochondrialdysfunction.
So then you got to ask yourselfwhat is causing the metabolic
disease?
(31:52):
So nine out of 10 Americanshave metabolic or metabolically
challenged, meaning they're notmetabolically healthy, and
that's the first step in therapid progression of cancer.
So then you got to ask yourselfwhat's leading to that?
So the issue of oral hygiene.
You know it's been known forover 100 years now that people
with gingivitis, periodontaldisease, oral dysbiosis, have
(32:14):
about a 10-time higher risk ofheart attack, stroke and
all-cause mortality, and we callthat the oral systemic leak.
But let's talk about the rootcanals in cancer.
Speaker 2 (32:25):
Yes.
Speaker 1 (32:26):
And if you go and you have to understand what a root
canal is, If you develop atoothache, you go to the dentist
, they'll typically refer youout to the dentist, they'll
typically refer you out to anendodontist and you've got an
infection right.
You've got nerve cells in theroot of the tooth that are
sensing pain and that pain istypically if it's not from
trauma, it's from bacterialtranslocation and an infection.
(32:48):
So what they do is they take thenerve root out of the tooth.
It's a root canal.
They canal down, they take theroot out of the tooth, so now
you no longer feel the pain, andthey also remove the blood
supply to that tooth.
And then they send you home andput you on an oral antibiotic.
And they must have forgottenthat 10 minutes before that they
(33:09):
took out the blood supply tothat infected tooth.
So the oral antibiotic, it goessystemic but it's not getting
to the site of infection.
So now you still have aninfected tooth, but now you've
got dead tissue, because withoutnerve supply and without blood
supply, that tooth, that tissue,that crystalline tissue in your
(33:30):
head, is now dead.
And dentists are the onlyprofessionals who think it's
okay to leave dead tissue in thebody.
If you develop a gangrenous toeor foot and you don't get rid
of it or don't amputate it.
Speaker 2 (33:46):
It will kill you.
Speaker 1 (33:48):
But yet they think it's okay to leave dead teeth in
the body and expect people tolive a happy life, and that
doesn't happen.
And so, number one, you've gotan asymptomatic infection in
that root canal tooth.
And these bacteria, they'reanaerobes, so they don't need
oxygen, but they're just eatingand metabolizing and spitting
out toxins.
And this goes back to reallytraditional medicine, ayurvedic
(34:12):
medicine, where it's known thatevery tooth, these acupuncture
meridians, are connected to anorgan and so the teeth are like
circuit breakers.
And if you've got a disruptionin that meridian you don't get
voltage, you don't get electronflow, you don't get nerve
conductance in that meridian.
And what happens?
Low voltage, low voltage, lowph, low oxygen, and that's
(34:35):
cancer.
My goodness, I'm shocked, yeah,and I tell you know, when people
come to see me no, that's thefirst thing I say and a lot of
people look at me like I've,I've lost my mind.
They go look, I don't have atoothache, I got cancer, help me
.
And I go look, the reason youmay have cancer is just go and
let's, let's figure step by step.
(34:55):
But I made a kind of a profoundcomment in that one podcast I
did and said the people thatcome to me with solid tumors
with metastatic disease.
I've never seen anybody that Ididn't send to a dentist and
people on that commented andthey go I've gone to the dentist
and I don't have any dentalinfections and I've had cancer
and I still got cancer.
(35:16):
Well, their dentist is lookingat an x-ray and sending them.
Oh, the x-ray comes back clear,it's unremarkable.
Well, an x-ray is not going topick up the radiolucency of an
asymptomatic osteo-necroticinfection in the jawbone so you
have to do a CT scan or a 3Dcone beam.
So if you go and let them doand it's not always a root canal
(35:36):
right Root canals are a problembecause 100% of them are
infected and it's dead tissue.
But the other problem could befrom an extraction from years
ago that left an unresolvedinfection and now you've got a
cavitation underneath thatextracted tooth, so it could be
cavitations.
A cavitation underneath thatextracted tooth, so it could be
cavitations, it could be rootcanal tooth.
(35:56):
It could be an asymptomaticinfection, an osteonecrosis
somewhere else in that tooth.
And almost without fail, if youlook at the acupuncture
meridians in the tooth chart,wherever you had the primary
tumor developed whether it'sbreast cancer, prostate cancer,
liver cancer, gi cancer it'llalways revert back to that tooth
along that meridian.
(36:17):
So all you have to do is justgo and get it extracted, find a
dentist who can use ozone gas,because you have to use a gas to
permeate the small tubules ofthe tooth and the jawbone to
kill the bacteria, and then theycan do a bone graft and regrow
that bone and make it strongenough now for an implant if you
(36:37):
need an implant for cosmeticregions.
But that's just the basics andso you know, when you get a
chance to understand thephysiology and the mechanism of
that, it makes perfect sense whyroot canal may be leading to
primary tumors and those aresolid tumors.
And so there's a differencebetween metastatic solid tumors
(36:57):
and bloodborne cancers likeleukemia, lymphoma, multiple
myeloma.
From my experience again, I'mnot an oncologist, I'm not a
cancer doctor, I'm a biochemistand physiologist.
But I've seen enough of thesecases to know that those are
caused from exposure to somechemical toxicant.
It's either mold and mycotoxins, it's exposure to things like
(37:17):
Roundup, glyphosate, herbicides,pesticides.
You've seen the class actionlawsuits now.
You've exposed to glyphosate orRoundup and you've developed
lymphoma leukemia.
You can get some money.
So a clear association andcausation by those.
So those are basically the boxwe have to check.
If you have a solid tumor, Isend you to a dentist, do a 3D
(37:39):
CD comb beam and then go to adentist who can extract the two,
clean up the infection and nowwe've got to get your body back
strong again, to where youcreate an environment where the
cancer cells can't grow.
But sometimes it's too latebecause unfortunately a lot of
the people that contact me havegone through chemo radiation
surgery and they're sent home todie on hospice and I can't
(38:03):
always rescue those patientsbecause they've been poisoned,
they've been radiated andthey've never addressed the
underlying root cause of theircancer and every disease process
reaches a point where there's apoint of no return.
So what we're trying to do isget this word out there and this
has been known for 60 years.
All you have to do is look forit.
(38:24):
But people would never in theirright mind again.
I taught in medical schools,I've talked to a lot of dentists
and this is never taught.
So if you don't know what tolook for, you're not going to
find it.
But if you know what to lookfor, there's a preponderance of
evidence out there dating back50, 60 years on the association
with dental infections, rootcanals and primary tumor
(38:46):
formation.
Speaker 2 (38:48):
You know you stated something about Ayurveda
medicine.
I'm a big, huge fan of Ayurvedamedicine and every organ in
your body is such an essential,every single organ is so
important.
Yet in today's world, themedical industry, we're so quick
to remove gallbladders and thisand that, and so I mean, how
(39:10):
effective is that?
I mean, are we shortening lifeby doing that?
Because I think gallbladder issuch an important?
But every other person that haspain there is just, you know,
cut off, remove.
Everything is just remove,remove, remove.
We're not really looking at allthese other you know research
and evidence.
Speaker 1 (39:31):
Well, when you're a hammer, everything looks like a
nail.
When you're a surgeon, you knowthey want to remove things and
they want to do surgery.
And if you've got an afflictingorgan, rather than try to
understand what's causing theaffliction, they just want to
take it out.
And for me, I believe that mycreator didn't make any mistakes
and I'm going to leave herewith what I can't do.
Speaker 2 (39:51):
That's right.
Speaker 1 (39:53):
Look, it's all connected because you go back to
how does the gallbladder work?
What causes the gallbladder tobecome clogged and gallstones
and dysfunction, it's thatsecretion and the recognition of
that acid load from the stomachand all that enters into the
portal at the same level as thepancreas, the liver, the
(40:14):
gallbladder, and so if you'renot getting that, the
gallbladder never gets thesignal.
Hey, I need to secrete a littlebile here to break down these
fats and so it becomes cloggedand then they take your
gallbladder out.
Now you can't digest fats, youcan't absorb basic nutrients and
it's a life of misery.
Because they're quick to react,they just want to take it out
(40:35):
and eliminate the symptoms.
But you haven't addressed theroot cause of why they had the
symptoms in the first place.
Speaker 2 (40:39):
That's right, dr Bryan.
What are the best ways fromyour perspective?
A person can increase bloodflow in the body, since that's
such an essential.
Speaker 1 (40:50):
Well, there are a number of vasoactive substances
in the body right.
There's vasodilators andthere's vasoconstrictors, and so
what we have to do is maintaina balance of both of those.
But nitric oxide is the mainvasodilator.
So if you can't, if you losethe ability to produce nitric
oxide now, you've lost thevasomotor activity and the
response to vascular reactivity.
So we just have to prevent theage-related decline of nitric
(41:12):
oxide production.
We've got to maintain a healthyoral microbiome, We've got to
eat nitrogen-rich foods and wehave to provide the body the
nutrients it needs.
And for the enzyme to makenitric oxide, it requires eight
different cofactors andsubstrates, one of those being
magnesium, and 75% of Americansare deficient in magnesium,
based on the government's owndata and I'm not a big believer
(41:35):
in government data, but you knowthat's real data and so 75% of.
Americans are deficient inmagnesium, the basic nutrient we
need for 800 biochemicalreactions and one of those is to
make nitroxyl.
So we focus on two things Dobasic micronutrient analysis,
understand what your body'smissing and then supplement it
(41:56):
back.
And then, number two,understand what your body's
exposed to.
What toxins are there presentin your body that's inhibiting
basic biochemical reactions?
Because people get sick for tworeasons, and two reasons only
they're missing something theyneed or they're exposed to
something that's toxic.
And if you address those twofundamentals, which is very
basic detoxify, replete missingnutrients, then the body heals
(42:20):
itself and the body basicallydoes what it's designed to do to
repair and replacedysfunctional tissues.
And we're regenerative bynature, the human body is
regenerative by nature.
And eliminate drug therapy andsynthetic compounds and pay
attention to what you put in andon your body.
Speaker 2 (42:38):
That's right If a person is diagnosed with cancer.
Dr Brian, what are the?
What are?
The first thing, what's thefirst thing on second and third
that they should do?
Speaker 1 (42:49):
second and third that they should do.
First, if it's a solid tumor,you know a primary tumor, or
even if it's, you know, advancedand it's metastatic disease and
they got, you know, cancer allover their body, the first thing
is go see a biological dentist.
And when I say go see abiological dentist, this isn't
your local dentist in your townor in your community.
You have to.
(43:11):
There's an organization calledInternational Association of
Biological Dental Medicine,iabdm.
And the website is iabdmorg andyou can put your zip code in
there and it'll give you a localbiological dentist in your area
that's familiar with this typeof dental and systemic medicine.
Then there's another reallygood dental group called IAOMT.
(43:33):
It's the InternationalAssociation of Mercury Toxicity,
IAOMT IOMT.
Speaker 2 (43:38):
IAOMT, i-a-o International.
Speaker 1 (43:44):
Association of Oral Medicine and Toxicology, and
then the other is theIntegrative Dental.
Speaker 2 (43:51):
Medical Society.
Speaker 1 (43:52):
And that's a really good group.
And these are the dentists thatare on the forefront of dental
medicine and who understand theroot cause in this oral systemic
link and know how to mitigateand remediate the infections the
dental infections where thenormal dentist is trained in.
today's dental schools don'tunderstand this at all, and so
(44:12):
that's what I do, then the otherthing is, you know, especially
if you've undergone chemotherapyand radiation, we have to
detoxify you.
That's right, because you'vebeen exposed to some really,
really toxic chemicals andradiation.
And we can put people in sauna,we can give them chelators, you
know, high-dose niacin and then, give them binders to.
(44:33):
If they mobilize the toxins,they need to excrete them.
But our main routes ofexcretion of toxins are
breathing.
We have to learn how to deepbreathe and take deep breaths.
We have to sweat.
That's one of the benefits ofsauna.
We have to stay hydrated withgood, clean, fluoride-free water
, and then we have to haveregular bowel movements.
So if we're not drinking a lotand if we're not urinating a lot
(44:55):
and not pooping and sweatingand doing deep breathing, we get
a buildup of toxins.
Speaker 2 (45:00):
And that's cheap right, that's costly.
These are just normalbiological responses, that's
right, we just have to look outfor what about fasting?
Yeah, how effective is fasting.
Speaker 1 (45:13):
Look again.
Everything I do is based onwhat's published in the
scientific and medicalliterature and there's enormous
benefit from intermittentfasting.
Caloric restriction is probablythe most powerful thing you can
do to improve longevity Caloricrestriction.
Caloric restriction Caloric yeah, so eating less calories.
You know, everything in the USis based on a 2,000-calorie diet
(45:34):
and everybody's different,right?
If you're a well-trainedathlete and you're competing in
the Olympics, you need toconsume a lot of calories to
fuel you during your event.
But if you're the normal couchpotato American, then you don't
need to eat a whole lot ofcalories because you're not
burning them and what happens isyou're going to store this fat.
But I do an 18-hour fasttypically every day.
(45:57):
This is sometimes difficult whenI'm traveling in different time
zones, but I think what isclear is that when you do the
intermittent fasting and you gofor these prolonged periods, it
completely rewires yourmetabolism and upregulates these
longevity genes and inducesmitochondrial biogenesis and
improves mitochondrial ATPproduction and it clears out
(46:17):
these what we call zombie cells.
And so you have these old cellsthat aren't functioning and we
have a process called autophagy.
It's called self-eating.
When we do intermittent fasting, or even 24-72 fasting,
autophagy is turned on and westart eating up these old
dysfunctional cells and wegenerate nitric oxide and we
(46:39):
mobilize stem cells and wereplace those old zombie cells
of senescent cells with cellsthat actually function.
Speaker 2 (46:45):
My father is big on that.
Speaker 1 (46:47):
Yeah, no, look, it's been life changing for me
because I, you know, we weretold you know, breakfast is your
most important meal of the day.
You have to eat breakfast.
But I mean, we've beenmisinformed so much by the
so-called policy makers that Idon't believe anything they say
anymore.
Speaker 2 (47:04):
That's right.
Question authority.
Speaker 1 (47:06):
Yeah, absolutely.
Speaker 2 (47:07):
Yeah, what should people look for when considering
nitric oxide supplements?
Speaker 1 (47:14):
Yeah, look, that's a loaded question and it's
confusing.
You know, I've been doing thisfor almost 30 years and I'm
pretty well informed and I goand look and see what's online.
If you just Google nitric oxidesupplements, you're going to
get a laundry list of all these,and so it's what comes up.
First are the companies who paythe most money.
First are the companies who paythe most money, and mostly
(47:36):
these companies who pay the mostmoney are spending more money
on marketing and no money onscience and understanding the
underlying problem of why peopleare nitric oxide deficient.
So about 95, 99% of theproducts on the market that are
sold as nitric oxide productsare placebos in terms of nitric
oxide.
Wow.
So, and the reason is that thesecompanies don't understand the
(47:56):
underlying biochemistry and thecomplexity of the science.
They just read our article andgo oh well, l-arginine is how
you make nitric oxide, so youget all these products with
L-arginine or L-citrulline.
And then beets came up.
You know, a hero vegetable inthe 2012 Olympic Games.
So people are selling beetrootproducts and beetroot powder and
(48:17):
things like that, and I'vetested all these and they're
basically placebos.
That's right.
All they do is turn your pee andyour poop red and cause a lot
of anxiety.
People think they're having adream.
That's hilarious.
I can't tell you how many callsI've gotten from that.
What I've tried to do over thepast 15 years is how does the
consumer know?
(48:37):
Because, based on the DietarySupplement, health and Education
Act, what we called the SHEAback in the 90s every supplement
manufacturer basically can saythe same thing May support
healthy blood pressure, sexualfunction it's called structure
function claims.
So all these companies,including myself and my
companies, we can't make drugclaims because we're supplements
(48:59):
.
So how do you identify aproduct that actually works?
And so supplements fall in thecategory of nutraceuticals right
Nutrients that supplement orprovide therapy.
Soutical means therapy.
So I trademarked a term which Icalled nitroceuticals.
It's nitric for nitric oxide,and so all of my products are
(49:22):
nitroceuticals because itproduces nitric oxide and we can
quantify, we can detect, we canverify nitric oxide gas coming
off my products and they'renitroceuticals, they aren't
nitroceuticals, they'renitroceuticals, they aren't.
They aren't nitroceuticals,they're nitroceuticals.
And so I encourage people lookfor, look for products that
actually produce nitric oxidegas.
(49:43):
So if your body can't make it,then I'm going to do it for you,
and this is hormone replacementtherapy at its very best, if
you're.
If men can't make testosterone,what do we do?
We give them testosterone.
We don't give them DHEA andhope their body can make
testosterone out of it.
We don't give them HGH and hopetheir body stimulates
testosterone.
That's their problem they can't.
They've lost the ability to doit.
(50:04):
And it's the same thing withnitric oxide.
The reason people are nitricoxide deficient is they can't
utilize arginine.
They don't have the right oralbacteria to convert any nitrate
and beet juice into nitric oxide.
You can't make stomach acid tomake nitric oxide, so no matter
what you give them, they can'tmake it.
So that's what we do.
That's different is, if yourbody can't make it, then we do
(50:27):
it for you and but we also fixthe reason your body can't make
it.
Spending 20 years working onthese enzymes that make nitric
oxide, I know how to restore thefunction, so we put that in our
technology and we're restoringthe oral microbiome.
Speaker 2 (50:41):
That's amazing, Dr Bryan.
We've talked about the adultsbriefly.
I know we're almost out of time.
I want to talk about thechildren Now.
I have a two-year-old and a10-year-old.
How can mothers and the fathersand the families that are
watching maintain the health andthe nitric oxide of their
children?
What are some things that wecan do to, you know, keep them
(51:01):
healthy.
Speaker 1 (51:03):
Well, it starts at conception.
You know the mother and thefather have to have good
nutrients.
So you've got a viable cell,viable sperm, and then,
especially the mother, duringthose nine months of gestation,
you have to have good nutrition,limit your exposure to toxins,
so you're creating anenvironment for that baby to
grow and thrive and haveeverything it needs.
And then, upon birth, you knowwe need to breastfeed.
(51:25):
There's clear healthdisparities between breastfed
and formula fed babies.
So and I understand, there'scertain times when women can't
breastfeed, their milk doesn'tcome in or other reasons Most
important thing, give the babygood nutrition, but
breastfeeding, it's nature'smost perfect food, god give it
and then you know when theystart eating solid foods.
You know, certainly do not giveantacids to a baby, even though
(51:48):
they may be prone to spitting upand regurgitating at times.
But avoid antacids and just youknow again.
Good, high quality foods, notprocessed foods, good fats, lots
of protein.
You know baby's metabolicdemands as they're growing may
need a little bit more carbsthan kind of a full grown adult,
because they're reallymetabolically much more active.
(52:10):
But, yes, basic good nutrients,elimination of toxins and
physical activity love that andavoiding fluoride avoiding.
Now there's data I think there's40.
There's a meta-analysisrecently produced showing, I
think, 40 independent studiesshowing that fluoride lowers the
iq in kids that's right.
(52:30):
I mean you've got it.
This is awful, and I think,with this new administration and
an rfk going in there, you knowwe're going to start
eliminating fluoride in ourmunicipal water and you know, I
spoke before the American DentalAssociation last summer and I
think we're finally getting theattention of the ADA.
And so just because you didthis 100 years ago doesn't mean
it's still sound science today.
We can do better.
Speaker 2 (52:52):
Yeah, I have been rejecting that since my eldest
was born.
He's 11.
And I kid you, not 11 years ago, when you said no fluoride to
the dentist, oof.
Speaker 1 (53:02):
It kicked you out, right.
Speaker 2 (53:03):
Yeah, it did.
I was looked at as a crazy madwoman, but you know.
Speaker 1 (53:08):
God told me, your intuition that's right, that's
right, dr Bryan.
Speaker 2 (53:14):
It's been such an honor.
Thank you so much.
The information is amazing.
I've learned so much from you,as the audience have, and I
appreciate you.
I'll link everything so thateverybody knows where you are
and how they can definitelyreach you, because you're such
an important person.
You're like God given.
This is God's work, becauseyou're such an important person.
Speaker 1 (53:34):
You're like God, given this is God's work, I feel
we have an obligation andresponsibility to get, because
it's education and it'sknowledge, and you know,
knowledge is power, but only ifyou, if you act on it, and so
there's a lot of misinformationout there and let me just plug
my upcoming book.
I got a new book coming out herein a couple of weeks called the
Secret of Nitric Oxide andreally in that book I tell, I
chronicle what nitric oxide is,how it was discovered, what
(53:56):
we've learned, and really talkabout kind of the part
autobiographical of thediscoveries we've made and how
we've got to where we are today.
But the purpose of the book isto empower the reader to
understand these things thatthey may not have even
considered and to take actionand do these simple things and
to maintain optimal nitric oxideproduction and you'll see their
(54:16):
life transform.
Speaker 2 (54:19):
That's right.
And before we go, there's thisone question that I ask all the
professionals on my show, andit's going to ask you this
question If there was onesupplement that you would take
and give it to your children,what would that one supplement
be?
Speaker 1 (54:37):
Well, look, you're asking a strong person.
Speaker 2 (54:41):
I'm saying magnesium, but I would love to know your
perspective.
Speaker 1 (54:47):
Well, no, I mean based on just the work.
If I'm limited to one, I wantto enhance my nitric oxide.
So I would take my N1O1 lozengebecause it contains magnesium.
It produces nitric oxide, andwhen you have adequate blood
flow, adequate tissueoxygenation, adequate
mitochondrial function, lowerinflammation, no oxidative
stress or immune dysfunction,then the body can function.
(55:09):
And so that's what I take.
That's what I've been takingnow for more than 20 years, even
some early prototypes of it,but it's our nitric oxide
generating lozenge.
Speaker 2 (55:18):
That's your brand.
Speaker 1 (55:19):
That's my brand N101.
Speaker 2 (55:21):
Okay, and if you weren't limited to one?
Speaker 1 (55:26):
The next would be iodine.
There are 12.5 milligrams ofiodine a day because the
American diet is completelydepleted of any iodine.
95% of Americans are deficientin iodine.
There's iodine receptors onevery cell.
You need iodine to make stomachacid in the palloric cells.
You need stomach acid toconvert thyroid T4 to the rise
of autoimmune disease my goshPart of our immune dysfunction.
(55:49):
Iodine is antibacterial, so ifyou develop iodine deficiency,
then bad things are going tohappen.
So I think that's a veryimportant, very neat nutrient.
But those are my go-tos.
Speaker 2 (56:01):
Awesome.
Well, thank you so much.
I appreciate you and you have ablessed day.
Speaker 1 (56:06):
Thank you very much.
Same to you.
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