This week on The Genetics Podcast, Patrick is joined by Andres Moreno-Estrada, population geneticist and head of the Human Evolutionary Genomics Lab at LANGEBIO in Mexico. They discuss the creation and insights of the Mexican Biobank, the genetic diversity of Latin America, ancient human migration, and the role of locally-led research in shaping public health and scientific equity.
Show Notes:
0:00 Intro to The Genetics Podcast
00:58 Welcome to Andres
01:56 Andres’ motivation to pursue genetics
03:01 How and why Andres established the Mexican biobank with genotyping of more than 6,000 people
07:25 Surprising findings on ancestry and regional similarities from the Mexican biobank
09:26 Links between Indigenous ancestry, BMI, and disease-related traits
12:36 Reconstructing population history from the Mexican biobank
20:16 Tracing a single ancient contact between South America and Polynesia through shared Indigenous DNA
21:58 Collaborative genomics efforts across Latin America and the launch of a regional Human Cell Atlas
26:39 How biobanks can inform national health decisions and why prioritization is the missing link in Mexico
32:10 Public health applications of genetic data and the need for local and regional biobanks
35:17 How ancient DNA reveals early cultural mixing and the deep roots of Mexico’s Day of the Dead traditions
39:12 Closing remarks and a call for support and investment in locally-led science across Latin America and beyond
Find out more
Moreno Lab (http://www.morenolab.org/)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
Popular Podcasts
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Law & Order: Criminal Justice System - Season 1 & Season 2
Season Two Out Now! Law & Order: Criminal Justice System tells the real stories behind the landmark cases that have shaped how the most dangerous and influential criminals in America are prosecuted. In its second season, the series tackles the threat of terrorism in the United States. From the rise of extremist political groups in the 60s to domestic lone wolves in the modern day, we explore how organizations like the FBI and Joint Terrorism Take Force have evolved to fight back against a multitude of terrorist threats.