This week on The Genetics Podcast, Patrick is joined by Benny Sorensen, CEO of Hemab Therapeutics. They discuss how Hemab is reimagining clotting therapies by centering patient voices, how persistence and being “unreasonable” led to their first program, and the value of their multi-modality and collaborative approach.
Show Notes:
0:00 Intro to The Genetics Podcast
00:59 Welcome to Benny
01:49 Reimagining blood clotting therapies by listening to lived experience and embracing the biotech revolution
04:27 How persistence and patient voices sparked Hemab’s first drug development program
07:13 Overview of Glanzmann Thrombasthenia (GT) and Hemab’s antibody-based approach
10:09 Evolution of hemophilia treatment and neglected blood clotting disorders
14:18 Genetic and gender considerations around bleeding disorders
17:41 Hemab’s range of therapeutic modalities and the value of collaboration
21:00 Why deep domain expertise drives Hemab’s strategy and success
22:55 Lessons from the drug development process
24:16 Global insights into gender bias, health inequality, and bleeding disorder care
26:46 Upcoming milestones at Hemab
29:52 Lessons from running natural history studies to capture the patient experience
33:25 Redefining the patient journey through data
34:40 How Benny’s experience at Alnylam Therapeutics shaped his “unreasonable” leadership
38:16 Reflections on being a father and a CEO
40:38 Closing remarks and Benny’s commitment to thoughtful drug development
Find out more
Hemab Therapeutics (https://www.hemab.com/)
Hemab trial register (https://shorturl.at/8AAQN)
Please consider rating and reviewing us on your chosen podcast listening platform!
https://drive.google.com/file/d/1Bp2_wVNSzntTs_zuoizU8bX1dvao4jfj/view?usp=share_link
Popular Podcasts
Dateline NBC
Current and classic episodes, featuring compelling true-crime mysteries, powerful documentaries and in-depth investigations. Follow now to get the latest episodes of Dateline NBC completely free, or subscribe to Dateline Premium for ad-free listening and exclusive bonus content: DatelinePremium.com
Stuff You Should Know
If you've ever wanted to know about champagne, satanism, the Stonewall Uprising, chaos theory, LSD, El Nino, true crime and Rosa Parks, then look no further. Josh and Chuck have you covered.
Law & Order: Criminal Justice System - Season 1 & Season 2
Season Two Out Now! Law & Order: Criminal Justice System tells the real stories behind the landmark cases that have shaped how the most dangerous and influential criminals in America are prosecuted. In its second season, the series tackles the threat of terrorism in the United States. From the rise of extremist political groups in the 60s to domestic lone wolves in the modern day, we explore how organizations like the FBI and Joint Terrorism Take Force have evolved to fight back against a multitude of terrorist threats.