The Great Antidote
Adam Smith said, "Science is the great antidote to the poison of enthusiasm and superstition." So join us for interviews with the leading experts on today's biggest issues to learn more about economics, policy, and much more.
Episodes
In this final episode of The Great Antidote, I sit down with my mom, Veronique de Rugy (does this feel like a Mr. Big name reveal for some of you?!), to reflect on the podcast and the remarkable journey of the past five years. Together, we revisit how the show started, the ideas that shaped it, the moments that changed me, and the people whose support made everything possible. This episode is a reflection on learning,...
Philosopher Rebecca Lowe (Mercatus Center) joins me to do an ideas-only deep dive: what freedom really is, why it matters, how it intersects with equality, and how to tell coercion from choice. We talk charitable argument (steelmanning), the social value of clear definitions, and Rebecca’s agent-focused view of freedom—plus why doing something freely can have value even when the act is bad.
Why is D.C. trying to shut down a rideshare app that pays drivers more and charges riders less? Jack Nicastro of Reason joins to unpack Empower’s battle with regulators, what “innovation vs. permission” means in real life, and how markets—not mandates—keep people safe.
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Is tech panic new—or just history on repeat? Judge Glock (Manhattan Institute) walks through what past tech scares (lead gasoline, CFCs, TV) got right and wrong, why “externalities” matter more than vibes, and how to think about AI regulation today—transparency mandates, liability vs. preclearance, “AI pauses,” and realistic optimism. We end with his own journey from socialism to markets.
Markets don’t work without trust. Tawni Ferrarini joins Juliette Sellgren to explore how honesty and reputation make exchange possible — from medieval trade networks to blockchain and Amazon reviews — and why decentralized trust systems matter in today’s economy of polarization, misinformation, and weak institutions.
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AEI Economist Derek Scissors joins Juliette Sellgren to unpack the reality of China’s economy, U.S.–China relations, and whether China is truly a threat. From demographics to debt and political control, Scissors explains what’s really driving China’s trajectory, and why it matters for America’s future.
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This week, Juliette Sellgren sits down with Martina Bacik, the 21-year-old founder of the Economics Olympiad that has grown to 120,000 students in 35+ countries, and Tawni Hunt Ferrarini, coauthor of Common Sense Economics. Together they explore why teaching economics early matters, how competitions and books ignite curiosity, and what inspiring young people can teach us about building a hopeful, prosperous future.
Why does freedom matter? How can we defend it in an age of rising authoritarianism? In this episode, I sit down with Tom Palmer to explore the ideas, virtues, and strategies that keep liberty alive.
We cover:
· The rise of authoritarian movements and global threats to liberty
· The morality of freedom: how to know what to fight for and when
· January 6th as a failure of duty, and what true constitutional...
In this special episode of The Great Antidote, Amy Willis of Liberty Fund takes the mic to interview Juliette Sellgren, the voice behind the show. Together, they reflect on the evolution of the podcast—from its early days to the hundreds of guests it has featured—and how Juliette herself has grown in the process.
They talk about what it means to foster curiosity, how Juliette approaches reading (and recommends you do, ...
What happens when people stop trusting rules—and start rewriting them?
In this episode, we are joined by economist Edward Lopez about the life and legacy of James M. Buchanan, the Nobel Prize-winning founder of public choice economics. We begin by unpacking Buchanan’s biography and intellectual roots: what shaped his worldview, who influenced his thinking, and why his work remains foundational to understanding governme...
What makes some states thrive while others trap people in place? And what does it really mean to be free to move, grow, and flourish?
In this episode, I talk with economist Justin Callais about the deep connections between personal fulfillment, economic mobility, and institutional quality. We begin with the personal: why real change starts internally, and how self-mastery and agency are prerequisites for meaningful, ex...
Remember the Amazon HQ2 frenzy? When nearly every U.S. state competed to become Amazon’s next home, offering billions in tax breaks and incentives? I do — I grew up right next door to Crystal City, Virginia, the site Amazon ultimately chose.
In this episode, I talk with economist Peter Calcagno about targeted economic incentives—the controversial policy tool that fueled the Amazon HQ2 bidding war and countless other co...
What if modern economics has overlooked what truly makes us human?
In this episode, Bart Wilson joins us to explore humanomics—an approach to economics that reintroduces meaning, culture, and moral judgment into how we understand economic behavior.
We talk about how economists miss the mark by assuming too much about how rational we really are—and too little about what it means to be human.
Wilson shares insights from hi...
What is it like to grow up under a dictatorship? The speakers of The Dissident Project don’t have to wonder — they’ve lived it. And they’ve escaped.
In this episode, Grace Bydalek joins us this week to discuss her work with The Dissident Project, which brings survivors of authoritarian regimes into American high schools to share their powerful, firsthand stories. From Cuba and Venezuela to Russia and beyond, these voic...
Ryan Streeter is the executive director of the Civitas Institute at the University of Texas at Austin. Today, he tells us about his time in the intersection of think tanks, government, and academic communities. We talk about cities, the importance of mobility and growth, how to foster those characteristics, skepticism of government, and living in and creating a community that fosters social cohesion and critical think...
We’ve talked about objectivism before on the podcast, but that was fairly introductory. Today, for the first time ever, I host two guests on the podcast to discuss the limitations of objectivism and where it fails to depict the good life. We talk about how they got interested in Rand’s thought, how they philosophically dealt with works that were mostly fiction, and where their philosophy, individualistic perfectionism...
Join us today for a fun conversation about all things government, UK and US, with Lord Daniel Hannan of Kingsclere!
Lord Hannan is a member of the House of Lords. Today, we talk about how the U.K.’s legislative is structured, what is up with executive power, the importance of the West and cohesion on the freedom front, and the idiocy of tariffs.
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Bob Ewing is the founder of the Ewing School and hosts a Substack called Talking Big Ideas (go check it out). He has also gifted me most of the great books that I’ve read.
Today, we talk about how he got started and how many of the great lessons in life are learned. We talk about counter-intuitive ideas, how to find the answers to them, and how to effectively communicate them. He talks to us about kettle bells and quo...
We talk a lot about civil society and the importance of local, communal networks which hold us up when we’re down and inspire us to be good, striving members of society. But what does that actually look like? How do civil institutions get built, and what does it take?
Today, I’m excited to welcome Rachel Ferguson to the podcast. She is the director of the Free Enterprise Center at Concordia University in Chicago and a...
Jo Jensen is the founder of MovieGoer and she’s currently the SVP of Digital and Entertainment Strategy at Touchdown Strategies, a PR firm. and is an Aspen Institute Civil Society Fellow. Since all fellows have ventures over there, she’s currently writing a book called “America Has a Girlfriend Problem.”
Today, we talk about the anxiety of my generation and how to unplug, attempting to grow comfortable with discomfort...
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