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July 8, 2025 38 mins

In their first podcast since going public, Omada Health CEO Sean Duffy joins us to reflect on the journey to bend the curve of chronic disease.

From walking away from the traditional PMPM model to staying grounded in clinical outcomes, Sean shares hard-earned lessons from over a decade of building Omada—from a startup in Rock Health’s Chinatown office to IPO. 

We cover:

🔧 Killing PMPM before it killed them (and the business model shift that made Omada viable)

🎯 Designing digital experiences around actual outcomes and not just engagement

💡 What sets Digital Health 2.0 apart, and why the next wave of companies needs to focus on care delivery, not just navigation or access 

📈 What going public taught Sean about readiness, discipline, and running a mission-driven business at scale

About our guest:

Sean co-founded Omada in 2011 with the aim of merging medical trends and cutting edge technology to revolutionize health care of chronic disease as we know it. Today, he proudly serves as CEO and has been instrumental in steering Omada toward global recognition, such as being hailed a potential “medical triumph” by The New York Times, and one of Fast Company’s 50 most innovative companies in the world.  

A longtime devotee of healthcare and technology, Sean also founded a largely automated lifestyle business around Excel Everest, the interactive Microsoft Excel training tool he created. He formerly covered healthcare innovation as writer and editor for Medgadget, a popular medical technology blog.

As CEO of Omada, Sean cares deeply about honing the organization’s exceptional products, values-driven approach to healthcare, and the innovative ways in which primary care can continue to better humanity.

More recently, Sean has been spending more and more of his free time learning how to build and fly first-person view drones.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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