The PillPack Founders Are Back for Round Two | Co-founder and Former CEO of PillPack TJ Parker

What does one do after selling their company to Amazon for $1 billion? Start a new one, of course.

In this episode, Halle sits down with TJ Parker, pharmacist, entrepreneur, and advocate for consumer-centric digital health. After co-founding PillPack and selling it to Amazon, TJ stayed on for four years helping build Amazon Pharmacy. Now, he’s back at it with General Medicine, a new company focused on making care as seamless as any other online transaction.

We cover:

🧾 Why pricing opacity and short-term incentives make care so frustrating

📦 What TJ learned from building PillPack—and how the Amazon acquisition actually played out

🏥 His vision for General Medicine, and why his second time around feels more like sport than survival

📉 The wild ride of taking on PBMs (and winning)

🪄 The one change he’d make to fix healthcare’s misaligned incentives

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About our guest:

TJ Parker is a general partner with Matrix and is the co-founder and former CEO of PillPack. As CEO of PillPack, in just five years, TJ raised over $100M in financing, grew the company to more than a thousand employees, and successfully sold the business to Amazon for $1 billion in 2018. Today, TJ is focused on starting, investing in, and advising other healthcare and consumer focused businesses. Most recently, he founded and is the lead investor in General Medicine.

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