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January 20, 2025 9 mins

In this episode of The History AI Podcast, we dive into the extraordinary story of the Blue Fugates of Kentucky, a family whose striking blue skin became a local legend and a case study in genetics. Discover how a rare condition called methemoglobinemia, combined with the isolation of Troublesome Creek, created a unique genetic phenomenon that has fascinated scientists and historians for generations. Join Chuck and Marco as they unravel the science behind this rare disorder, explore the Fugates’ legacy, and share how a little blue pill changed everything. Perfect for history buffs and science enthusiasts alike, this episode offers a compelling blend of storytelling, medical history, and Appalachian culture. Don’t miss it!

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