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September 5, 2025 41 mins

This is the fourth of four episodes in a special series dedicated to the 2025 NVCA Award Recipients. To learn more about the NVCA and their work in crafting the future of Venture Capital, visit their website at https://nvca.org/. 

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In this episode of The Innovators & Investors Podcast, host Kristian Marquez sits down with Matt Schappell, principal investor at Frist Cressey Ventures, to explore the firm’s focused approach to healthcare innovation.

Matt shares the origins of the fund, founded by Senator Bill Frist and Brian Cressey, highlighting their mission to invest in early-stage companies that leverage technology to improve healthcare outcomes while prioritizing the patient experience.

They discuss the challenges of the healthcare ecosystem, including rising costs, workforce shortages, interoperability issues, and the slow adoption of technology.


Matt explains how Frist Cressy Ventures supports startups navigating long sales cycles by leveraging their network of payers and providers to accelerate market entry.


The conversation also dives into the growing role of AI in healthcare, value-based care models, and the importance of leadership and culture within health systems.


Matt reflects on his unique career path from a healthcare family background to investment banking and venture capital, emphasizing the human-centered nature of healthcare as fundamentally a hospitality business.


Listeners will gain a comprehensive understanding of the current healthcare investment landscape, the strategic priorities for early-stage ventures, and the future potential of technology to reshape patient care.


Learn more about Matt's work at https://fcventures.com/


Connect with Matt on LinkedIn at https://www.linkedin.com/in/matt-schappell-445b55103/


Think you'd be a great guest on the show? Apply at https://finstratmgmt.com/innovators-investors-podcast/


Want to learn more about Kristian Marquez's work? Check out his website at https://finstratmgmt.com

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