Dr. David Carr, a renowned professor of medicine and neurology, discusses the risk factors and treatments for Alzheimer's and dementia. He highlights that primary insomnias associated with neurodegenerative brain diseases can accelerate brain decline. The lifetime risk of Alzheimer's in the mid-50s is 10%, rising to 30% with a family history. He emphasizes the importance of early diagnosis through biomarker tests like amyloid PET scans. Preventative measures include a healthy lifestyle, B12 supplementation, and medium-chain triglycerides. Recent treatments include Lecanemab, which slows disease progression. Dr. Carr also stresses the importance of caregiver support and ongoing research.
00:00 Introduction and Background
03:50 Understanding Dementia and Alzheimer's
09:02 Diagnosing Dementia and Alzheimer's
13:22 Prevention of Alzheimer's: Lifestyle Factors
23:40 Modifiable Risk Factors for Alzheimer's
28:08 The Potential Impact of New Treatments on Alzheimer's Disease
30:44 Introduction and Personal Connection to Alzheimer's
33:17 Small Vessel Disease and Dementia
35:26 Current and Future Treatment Options
38:18 Treating Symptoms vs. Treating the Cause
43:30 Exciting Research in Alzheimer's and Dementia
48:15 Importance of Autonomy in End-of-Life Care
53:08 Tips for Caregivers
58:40 Genetic Testing and Alzheimer's Risk
01:01:20 Importance of Research Participation
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