The DNA Test That Tells You How Fast You’re Aging—And How to Stop It

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Can you really slow down or even reverse aging? In this episode of The Longevity Leaders, Ryan Smith, founder of TruDiagnostic, breaks down the evolution of biological aging clocks and how cutting-edge epigenetic testing is reshaping longevity science. He explains how DNA methylation data can not only predict your biological age but also guide personalized strategies to slow or reverse the aging process.

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In this episode of The Longevity Leaders, Ryan Smith, founder of TruDiagnostic, takes us deep into the rapidly advancing science of epigenetics and biological age measurement. He outlines how TruDiagnostic is leveraging the world’s largest private epigenetic methylation database to develop second- and third-generation aging clocks that go beyond estimating age—they predict health outcomes, disease risks, and even pinpoint which organs are aging the fastest.

Ryan explains how aging is the greatest risk factor for nearly every chronic disease, and how the ability to quantify and intervene in that process through DNA methylation testing is revolutionizing preventative medicine. He shares the critical improvements made in the latest biological age clocks and introduces tools like the Symphony Clock that assess the biological age of different organ systems. The future of aging is no longer about guessing—it's about actionable, personalized longevity strategies grounded in hard data.

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Ryan Smith is the founder of TruDiagnostic, a health data company at the forefront of epigenetic testing and biological age diagnostics. With a background in biochemistry and a deep passion for longevity science, Ryan has built TruDiagnostic into the world's largest private epigenetic methylation database, serving over 25,000 patients and powering cutting-edge research in aging and chronic disease prevention.

Before launching TruDiagnostic, Ryan helped bring innovative peptide therapies to market, but his desire to measure long-term health outcomes led him to epigenetics. Today, he is a recognized leader in the development of second- and third-generation aging clocks, collaborating with institutions like Harvard, Yale, and Duke to unlock personalized longevity insights through DNA methylation. His work focuses on creating precise, predictive, and actionable biomarkers that help individuals and clinicians reverse biological aging and optimize health at the cellular level.

Ryan is on a mission to transform how we measure and manage aging, empowering people with the tools and data to take control of their healthspan—now, not decades from now.

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Website: https://trudiagnostic.com

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LinkedIn: https://www.linkedin.com/company/trudiagnostic

YouTube: https://www.youtube.com/@trudiagnostic

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