This episode discusses findings from a recent systematic review preprint, examining how the embryonic germ layer origin of various cancers may relate to differences in therapy response. Drawing on evidence from clinical trials and mechanistic studies, we explore patterns observed among mesoderm-, endoderm-, and ectoderm-derived tumors.
The conversation highlights how integrating developmental biology concepts into oncology may help inform treatment decisions and research design. This episode is intended for students, researchers, and clinicians interested in cancer biology, translational research, and personalized medicine.
Please note: The views of this podcast represent those of my guest and I, and do not constitute medical advice, recommendations or consultations. Please see a state certified and board certified professional for medical, advice and recommendations. We disclaim any loss in any way.
Link to Preprint: Embryonic Germ Layer Origin as a Potential Determinant of Cancer Therapy Response: A Systematic Review and Meta-Analysis of Contemporary Evidence | medRxiv
Note: Some of this episode's production involved the use of AI.
On Purpose with Jay Shetty
I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!
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