Live Stronger, Think Sharper, Age Smarter: The New Science of Longevity (Ep. 47)

In this episode of The Med Edit Podcast, Dr. Jessica Gray and Dr. Cari Sorrell explore the cutting-edge science of cognitive function and healthy aging — revealing how your habits today shape your brain, body, and longevity for decades to come.

From brain plasticity to breakthroughs in Alzheimer’s research, this episode blends practical, evidence-based advice with new frontiers in neuroscience and anti-aging medicine.

Segment 1: The Aging Brain

• Cognitive Fitness 101: Learn how neuroplasticity — your brain’s ability to adapt and rewire — protects memory and focus as you age.
• Lifestyle Matters: The doctors unpack the research on exercise, diet, and sleep, including why aerobic movement and strength training stimulate the brain’s growth factors (BDNF).
• Eat Smart for Brain Health: Explore the MIND and Mediterranean diets — and why reducing sugar and processed foods supports neuroplasticity.
• Stay Sharp: Discover how lifelong learning, social connection, and creativity build your “cognitive reserve.”
• Rest and Reset: Evidence-based sleep hygiene practices that enhance brain repair and long-term memory retention.

Segment 2: Emerging Research in Cognitive Longevity

• New Alzheimer’s Treatments: A look at the latest FDA-approved drugs, Lecanemab and Donanemab, and how they target amyloid plaques to slow cognitive decline.
• Cellular Senescence: The rise of senolytic drugs and their potential to reverse aging at the cellular level.
• Creatine for the Brain: Surprising evidence that creatine monohydrate may enhance short-term memory and reasoning in aging adults.
• Hearing and Dementia: New studies show hearing aids may reduce dementia risk by up to 50%.
• The Music Connection: Groundbreaking work from the MIND Lab shows how music and rhythm can reactivate memory pathways in dementia patients.

Rapid-Fire Myth Busting: FACT or MIS

Dr. Gray and Dr. Sorrell bust the biggest myths on brain and bone health — from collagen powders to crossword puzzles — and remind listeners that the most powerful anti-aging tools are still movement, mindset, and connection.

Book of the Week

A Short Guide to a Long Life by Dr. David Agus

A timeless resource on building daily habits for strength, resilience, and longevity.

Key Takeaways

• Challenge your brain with new learning, not repetition.
• Muscle mass is your greatest longevity investment.
• Nutrition and sleep drive long-term brain performance.
• Relationships, laughter, and optimism fuel healthy aging.

Resources Mentioned

• Harvard Health: Tips to Leverage Neuroplasticity
• NIH: Science Behind Sensory Loss and Dementia Risk
• PubMed: Creatine and Cognitive Function
• A Short Guide to a Long Life by Dr. David Agus

Continuing Medical Education (CME)

Clinicians — claim your CME credit for listening!

https://cmetracker.net/TTUHSC/Publisher?page=pubOpen&nc=7120399723#/myPortal

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LinkedIn: Dr. Cari Sorrell: https://www.linkedin.com/in/cari-sorrell-42545a7b/