The Metabolic Link

The Metabolic Link

Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.

Episodes

June 25, 2025 102 mins

What’s really causing America’s obesity epidemic? In this special debate episode of The Metabolic Link, two leading voices in metabolic health square off: Dr. Richard Johnson, renowned for his research on fructose metabolism, and Dr. Layne Norton, a PhD in nutritional sciences and expert on the energy balance model.
 
Moderated by host Dr. Dominic D’Agostino, the discussion dives deep into the biological roots of obesity, t...

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Join us for a Live Q&A on June 18th at 9am PT/12pm ET with Dr. Anthony Chaffee and also enjoy ad-free exclusive episodes, videos covering the latest science on metabolic health on therapy, and earn CMEs by clicking here.

In this episode, Dr. Anthony Chaffee—medical doctor, neurosurgical registrar, and nutrition educator—joins Dr. Dominic D’Agostino for a thoughtful exploration of the scientific rationale behind anima...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health and therapy, and earn CMEs here!

In this deeply personal and courageous episode of The Metabolic Link, we hear from patient advocate and podcast co-host Matt Baszucki, who shares how he endured—and ultimately overcame—type 1 bipolar disorder through a radical shift in treatment: ketogenic metabolic therapy.

A...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here!

If you’re a clinician, scientist, or anyone interested in taking a deep dive into the complexities of hormone regulation, this episode of The Metabolic Link Podcast is for you! Recorded live at Metabolic Health Summit 2024, this in-depth presentation by Dr. Kyle Gillett—dual board-certif...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com

In today's journal club episode, co-hosts of The Metabolic Link, Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break ...

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Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here!

In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Spencer Nadolsky—board-certified obes...

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Join us for a Live Q&A with Dr. Ovadia on March 31st at 12 PM PT / 3 PM ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of videos on metabolic health (including Dr. Ovadia’s presentation, Fanning the Flames: Inflammation, Insulin Resistance, and Heart Disease), CME opportunities, and more. Register here!

Dr. Philip Ovadia is a ...

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Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness.

In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto.

Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreak...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here.

What’s the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed ...

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What if we could target cancer at its metabolic core? In this episode of The Metabolic Link, Dr. Dominic D’Agostino is joined by Dr. Tomás Duraj, a physician and cancer metabolism researcher working alongside Dr. Thomas Seyfried.

Dr. Duraj is the lead author of a groundbreaking review on ketogenic metabolic therapy for glioblastoma, bringing together leading experts to explore how metabolic strategies could reshape cancer treatment.

...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com

Can a ketogenic diet revolutionize the management of type 1 diabetes? In this episode of The Metabolic Link, Dr. Ian Lake, a UK-based physician and type 1 diabetes advocate, shares his personal and professional journey in using low-carb and ketogeni...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes, watch 100s of videos on metabolic health, and earn CMEs here.

In this powerful and unfiltered episode of The Metabolic Link, we're sharing a full presentation by Chad Vanags, a former SaaS executive and entrepreneur who has turned his stage 4 lung cancer diagnosis into a mission to reshape the way we think about healing. Recorded live at...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here.

In this journal club episode, host Victoria Field is joined by Dr. Angela Poff and Dr. Dominic D’Agostino to dive into two groundbreaking studies shaping our understanding of metabolism and its role in health and disease. The team explores the nuances of a recent randomized controlled trial on ketogenic diets, free sugar r...

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Join our free Live Q&A with Lauren on December 18th and become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Register here!

In this episode of The Metabolic Link, host Victoria Field sits down with Lauren Kennedy West, a passionate mental health advocate and social worker who was diagnosed with schizoaffective disorder in 2016. Lauren reveals her extraordinary journey of using...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com

In this special episode of The Metabolic Link, we’re sharing an exclusive panel discussion from Metabolic Health Summit 2024, where leading experts dive into the science and real-world applications of allulose, a natural low-calorie sweetener with potential metabolic health benefits.

Fea...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com

In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com

In this episode of the Metabolic Link podcast, we are joined by Beth Zupec-Kania, an experienced dietitian and nutritionist with over 30 years in the field o...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com

In this episode, we're sharing a presentation from Metabolic Health Summit 2024 that dives into a groundbreaking experiment titled "Oreo vs. Statin," by researcher-educator Nick Norwitz, PhD. What started as a personal journey with metabolic health turned into a captivati...

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Did you know that nearly 60% of the average American's diet is made up of ultra-processed foods? This staggering statistic highlights a growing public health crisis linked to rising obesity rates and chronic diseases, not only in adults but our children too.

In this week’s episode of The Metabolic Link, we dive into a critical conversation with Todd Wagner, a passionate advocate for food safety and health reform. As t...

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Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here.

In this journal club episode of The Metabolic Link, we explore the cutting-edge "Metabolic Overdrive Hypothesis" with Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field, diving into the brain’s energy dysregulation in bipolar disorder. The featured paper, "The Metabolic Overdrive Hypothesis: Hyp...

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