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July 16, 2025 64 mins

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Our summer road trip down the Great River Road continues in this episode. We start just after Lake Pepin and make our way to the Mississippi’s confluence with the Ohio River at Cairo, Illinois. Along the way, I’ll comment on the following places: the Upper Mississippi River National Fish & Wildlife Refuge; Winona, Minnesota; in Wisconsin: Alma, Fountain City, La Crosse, and Prairie du Chien; Dubuque, Iowa, and Galena, Illinois; the Quad Cities of Illinois and Iowa; in southeast Iowa: Muscatine, Burlington, Fort Madison, and Keokuk; in Illinois: Nauvoo, Quincy, Grafton, Alton, Chester, Shawnee National Forest, and Cairo; in Missouri: Hannibal, St. Louis, Sainte Genevieve, and Cape Girardeau, plus a few places in between these. I obviously won’t be going into great depth about any particular place but instead want to give you a sense of the variety of attractions and experiences you can expect along the Mississippi River, with some picks about my favorite spots (and where to get good food and drinks). 

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