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April 29, 2025 62 mins

The Dual-Use Debate: Crafting Smarter Startups from the Start | The Pair Program Ep60

Today on The Pair Program, we’re joined by Gene Kesselman, Director of Mission Innovation Experimentation at MIT, and Jake Chapman, Managing Director at Marque Ventures. Together, they dive into the evolving landscape of dual-use technology and the future of defense innovation. Gene and Jake explore opportunities, tough realities, and bold reforms shaping tech development for mission and market impact.

Some of what we dive into:

  • Why dual-use strategy is more than just a category
  • Common pitfalls startups face in defense tech
  • How venture capital sees national security innovation
  • The critical role of non-dilutive funding and SBIR programs
  • Urgent reforms needed in government acquisition and budgeting processes

Tune in for real-world insights and sharp debate!

About Gene Keselman: Gene is a Lecturer at MIT Sloan School of Management, Executive Director of MIT Mission Innovation Experimental (MIx), and Managing Director of MIT’s venture studio, Proto Ventures. A seasoned entrepreneur and Air Force Colonel, he brings extensive expertise in innovation, defense, and dual-use technology strategy.

About Jake Chapman: Jake is the Managing Director of Marque Ventures, an early-stage venture firm focused on national security capabilities. He previously led a turnaround of the Department of Defense’s internal venture arm and serves as an adjunct at RAND, where he works at the intersection of finance and national security.

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