April 2, 2025 • 18 mins
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Speaker 1 (00:09):
Hey, everyone, welcome to another edition of Wisdom Wednesdays and
to the last of twelve of our series of anti
aging strategies. And today we are goining to talk about
mitochondrial dysfunction, and it's basically.
Speaker 2 (00:25):
The power failure behind aging.
Speaker 1 (00:27):
That's power for people who can't understand my accent, and
so mitochondrial dysfunction for me is probably the most important one,
just in my opinion, of those twelve hallmarks of aging,
because we know that the mitochondria are implicated in almost
(00:49):
every one of the major causes of death, and they
are also implicated in pretty much every mental health condition
that there is. Doctor Chris Palmer, who's a psychiatrist at
Harvard University, has written a brilliant book called Being Brain Energy,
and basically he shows quotes all of the studies that
(01:11):
show that damaged mitochondria or suboptimal mitochondria are present in
every mental health condition that there is. Now, let's get
back to the mitochondria. They are often known as the
powerhouses of the cell because they create the energy within
the cell, but their rules extend far beyond energy production
(01:35):
and understanding how that influences aging and really provides insights
into how we can maintain our vitality, increase our health span,
and prevent chronic diseases. So what are they? They are
specialized organelles. Organell is just a fancy name for a
substructure of the cell that has one or more and
(01:57):
are one and more clear functions. And so these are
specialized organelles within our cells, and they're responsible for producing ATP.
ATP is the primary energy currency of our cells and
therefore of us, and they achieve this ATP through something
called oxidative phosphorolization.
Speaker 2 (02:21):
So there's going to be a few big words. That's
just a little bit of a warning.
Speaker 1 (02:24):
But that's basically how we convert nutrients from food into energy,
and it's through something called or part of it's through
something called the CREB cycle. So cells with high energy
demands think about neurons in the brain and muscle cells,
they have numerous mitochondria to meet their energy needs. So
(02:45):
the more energy hungry a cell is, the more mitochondria
they tend to have. But they don't just the energy production.
They're also involved in critical processes like calcium signaling, which
is really important for keeping us alive, apoptosis, which is
that programmed sale death that we talked about in previous episodes,
(03:06):
and also the generation of reactive oxygen species. And their
unique feature is that they actually possess their own DNA
called mitochondrial DNA, and it's inherited maternally, so it comes
from the mum and that encodes essential components.
Speaker 2 (03:27):
For their function.
Speaker 1 (03:28):
And this really sets your mitochondria out from everything else,
the fact that they have their own DNA which you
actually get from the mother. And let's talk about mitochondrial
dysfunction and why it's important in aging. So as we
age this, the efficiency of our mitochondria actually declines, and
(03:51):
that leads to reduce the AT production atp sorry production
and increased reactive oxygen species generation. If you remember reaction
of oxygen species, they can create inflammation and all sorts
of nasty things. They basically cause oxidative damage to cellular
components including lipids, proteins in DNA within the cell and
(04:14):
that contributes to cellular senescence and tissue dysfunction. So if
you remember back cellular sinescence, that's like the zombie cells.
So basically, when your mitochondria loser efficiency, we get more
damage inside the cell and the cell turns into zombie cells,
and this decline in mitochondrial function is associated with a
whole host of age related diseases such as metabolic syndrome,
(04:39):
and metabolic syndrome basically increases your risk for a huge
amount of diseases, including cardiovascular disease, the biggest killer, and
we know that in powered mitochondrial function, it disrupts energy metabolism,
contributes to insulin resistance and obesity, which are hallmarks of
metabolic syndrome, but also kind of mitochondrial function and contributes
(05:03):
to neurodegenerative diseases because are neurons, because they're so energy hungry,
they are particularly vulnerable to mitochondrial dysfunction. And we know
now that defective mitochondria can lead to synaptic failure and
the death of neurons, as we see in Alzheimer's disease
(05:24):
and Parkinson's disease. And the other big thing that it
contributes to is cardiovascular diseases. So mitochondal dysfunction in cardiac
cells impers your heart function and contributes to hypertension, atherosclerosis,
and overall cardiovascular disease. And if you take those collectively,
cardiovascular disease neurodegenerate disease and metabolic syndrome, and in the
(05:47):
knock on effects of metabolic syndrome, that actually.
Speaker 2 (05:51):
Accounts for a huge portion of death.
Speaker 1 (05:55):
And that's why I think mitochondrial dysfunction is the most
important hallmark of aging. And we have this theory called
the mitochondrial free radical theory of aging, and that suggests
that a cumulative oxidative damage from these reactive oxygen species
over time leads to the functional decline of our mitochondria
(06:16):
and that drives the aging process. So let's talk about
the stuff that we can actually do. And first up,
of course, is regular physical activity. There is probably nothing
that you can do better for your mitochondria than regular
physical activity.
Speaker 2 (06:34):
Engaging in in.
Speaker 1 (06:35):
Regular exercise is a cornerstone for bolstering mitochondrial health. Physical
activity has been shown over and over again to improve
mitochondrial function and induce mitochondrial biogenesis, which is the creation
of new mitochondria.
Speaker 2 (06:55):
And so it has two things.
Speaker 1 (06:57):
It enhances the efficiency of your existence mitochondria and it
creates new mitochondria. And this adaptation is crucial for meeting
increased energy demands and improving our metabolic health.
Speaker 2 (07:10):
And we know that.
Speaker 1 (07:12):
Both aerobic training, particularly zone two, which is that's that
heart rate of sixty to seventy percent of your max.
But from a non technical perspective, you're exercising, you can talk,
but you can't sing, So you can talk in sentences,
but you're kind of breathing heavily and you can't sing.
(07:33):
If you can sing, you're in zone one. If you
can't talk in sentences, you're in zone three.
Speaker 2 (07:38):
A higher heart rate zone.
Speaker 1 (07:40):
And we know that this zone two, you it's basically
where aerobic metabolism is dominant, and that has been shown
to improve our mitochondrial health, can contribute a little bit
to mitochondria biogenesis. And interestingly, I read a study recently
where they took a bunch of people who weren't fit,
(08:02):
and they put half of them straight into resistance training,
and half of them they did eight weeks of aerobic
training in zone two before they went into resistance training.
Speaker 2 (08:13):
And then they looked at their.
Speaker 1 (08:15):
Strength training gains and muscle sized gains, and it turns
out that the people who'd done the aerobic training first
actually increased their strength and muscle maths quicker than the
people who went straight into the resistance training. And the
thinking is the aerobic training gave them a better functioning
mitochondria and some more mitochondria, and then that translated to
(08:41):
quicker benefits from the strength training. So let's talk about
high physical activity. Actually, oh sorry before we do that.
And high intensity interval training has shown to be very
very potent in stimulating mitochondrial biogenesis of the creation of
new mitochondria. So let's talk about the mechanism. One is AMPK,
(09:04):
and so basically AMPK stimulates mitochondrial biogenesis and enhances oxidative metabolism.
And the other thing, again we're getting a bit giky.
Here is PGC one alpha upregulation and PGC one alpha
If you really want to know what it is, it's
(09:24):
perioxysome proliferator activated receptor gamma coactivator one alpha, and this
is a master regulator of mitochondrial genesis. And this PGC
one alpha pathway is hugely important in our health and
studies have shown as I said, that both aerobic training
(09:46):
and high intensity interval training and resistance training improves our
mitochondrial content and function in our muscle, leading to improved
intinal insensitivity and reduce.
Speaker 2 (09:58):
Risk of metabolic disorder.
Speaker 1 (10:00):
And we also know that fasting and exercise both stimulate
mitochondria biogenesis and stress resistance in muscle cells and through
calcium signaling an AMPK activation.
Speaker 2 (10:14):
Right, that's geeky enough for the minute.
Speaker 1 (10:17):
Let's talk about calorie restriction and intermittent fasting, So reducing
your caloric intake without going into malnutrition or doing implement
intermittent fasting or time restricted feeding as some people call it.
Speaker 2 (10:32):
They have been associated with.
Speaker 1 (10:33):
Enhanced mitochondrial function and increase lifespan in various species, not
in humans, I hasten to add. But the mechanisms by
which this happens is that when we fast, we switch
from burning glucose to burning fat. This what we call
metabolic flexibility. And when you switch over to burning fat,
(10:55):
it actually stimulates the production of ketone bodies like beta
hydrox computury it and that actually serves as an energy
substrate and signaling molecule for the mitochondria. And what fasting
also does is it induces autopogy. I talked about that
in earlier ones. That's the cellular clean up process by
(11:18):
which the things inside the sale actually take damage mitochondria.
This is called mitophagy. And they take that damage mitochondria
and actually recycle them and create new mitochondria. So this
is that's the cellular recycling plant that's actually going on.
And this this is called cyclic metabolic switching theory. It
(11:41):
suggests that health benefits of intermittent fasting may actually be
better than those of continuous calorie restriction. And I actually
think that's a slam dunk because of that interplay between
ketone metabolism, mitochondrial adaptations, and autophogy.
Speaker 2 (11:58):
And I know I'm getting very.
Speaker 1 (11:59):
Geeky here, but I think it's important to understand these processes.
Now I link to this, you'll not be surprised to
hear that if intermittent fasting does this and through ketones,
going on a ktogenic diet where it's it's high fat,
low carbohydrate and moderate protein that stimulates beta hydroxy buttyate
(12:20):
and other ketones which then positively influenced mitochondrial function. And
we see this a katogenic diet really beneficial for Alzheimer's
disease in Parkinson's disease, probably because of the impact that
they have in the mitochondria in brain cells, and the
mechanisms are very similar. Add to intermittent fasting enhance mitochondrial
(12:42):
efficiency because the ktone bodies are really an excellent energy source.
An increase our at B production reduced oxidative stress. But
beta hydroxy butty in itself has actually been shown to
stimulate antioxidant defenses, which is really really important. And a
(13:02):
study combining a ketogenic diet with exercise actually showed that
there were alterations in mitochondrial function, including increased respiratory what's
called respiratory control ratio and ATP production in skeletal muscle,
as well as improvements.
Speaker 2 (13:20):
In metabolic health markers.
Speaker 1 (13:22):
So together with exercise and a ketogenic diet or intermittent
fasting can be very powerful double wami for your mitochondria.
Let's talk about pharmacological or supplement interventions. So NAD precursors
theoretically are good for the mitrochondry because we know NAD
(13:43):
plus is really important. So compounds that you'll see like
NMN plastered all over the internet and NR they are
thought to boost NAD levels. The fact they've been shown
to actually do that, and that's essential for our mag
to chondrial function. But if you don't want to spend
a shitload of.
Speaker 2 (14:02):
Money on NMN and NR.
Speaker 1 (14:05):
You can actually just take some B vitamins because NMN
and NAR are actually converted in the gut to vitamin
B three, which is nicotinic acid. And so you can
either go out and spend a shitload of money on
NMN and NR, or you can just take vitamin B three.
Speaker 2 (14:26):
I know what I would do.
Speaker 1 (14:28):
Another supplement that's pretty promising, And actually I have started
playing with this methylne blue because it has been shown
to actually stimulate the mitochondria through its actions on the
crab cycle. It actually by cut passes for those who
are geeky, complexes one in three in the electron transport
(14:51):
chain and actually stimulates the crab cycle, leading to increased
ATP production and improves cellular energy metabolism through the mitochondria. Okay,
now if that's not kiky enough, let's now talk about
low level light therapy or infrared and near infrared light therapy,
(15:12):
so near infrared light and that's also known as a photobiomodulation.
That is basically applying low level red light to near
infrared light and to stimulate cellular function. And what it
does is it works on something called cytochrome C oxides
(15:36):
and that is a key enzyme in the mitochondrial electron
transport chain. And there is a heap of research now
I that shows that near infrared light actually boosts the
function of your mitochondria, and that is something I was
so convinced by the research. And I have a panel
(15:57):
that does both red light and near in for red light,
because the research for me is very very compelling about
improvements in mitochondrial function. And we are now even seeing
near infrared light helmets of certain way of lengths significantly
improving symptoms in both Parkin's disease and Alzheimer's disease. And
(16:22):
basically what happens is that at light passes goes through
your skeleton and actually stimulates goes it deep inside of
your body and stimulates your mitochondria and certain parts of
the electron transport chain, and that leads to increased energy
(16:43):
production and improves cellular energy metabolism. And the other thing
that near infrared light does is it releases nitric oxide,
and that actually helps to improve blood flow and reduces
oxidative stress.
Speaker 2 (16:57):
And studies have.
Speaker 1 (16:58):
Shown that infrared light penetrates human tissues and benefits mitochondrial
function as I say it, and it can improve things
like mitochondrial dynamics and quality control following ischemia, stroke, cardiac
arras so I actually was using it post my heart
(17:22):
surgery and also for overall brain function, cognitive function. It's
actually been shown to help people recover from straight stroke
and neuro degenerative diseases. So hink conclusion, lots of big mouthfuls,
but basically what we know is our mitochondria are absolutely
(17:45):
key to cellular health and longevity, and doing things like
regular exercising, intermittent fasting, low carbon particularly keathogenic diets, some
potential pharmacology, and near infrared light therapy can all really benefit.
And while studies haven't been established it because they're really
(18:06):
hard to do, I actually think that these things are
additive because they work on slightly different pathways in our mitochondria.
Speaker 2 (18:15):
So I think if.
Speaker 1 (18:16):
You're doing all of them, you're going to get better
benefits than if you're just doing one or two. So
that's it for this week, folks, Catch you next time.
Hey, everyone, welcome to another edition of Wisdom Wednesdays and
to the last of twelve of our series of anti
aging strategies. And today we are goining to talk about
mitochondrial dysfunction, and it's basically.
Speaker 2 (00:25):
The power failure behind aging.
Speaker 1 (00:27):
That's power for people who can't understand my accent, and
so mitochondrial dysfunction for me is probably the most important one,
just in my opinion, of those twelve hallmarks of aging,
because we know that the mitochondria are implicated in almost
(00:49):
every one of the major causes of death, and they
are also implicated in pretty much every mental health condition
that there is. Doctor Chris Palmer, who's a psychiatrist at
Harvard University, has written a brilliant book called Being Brain Energy,
and basically he shows quotes all of the studies that
(01:11):
show that damaged mitochondria or suboptimal mitochondria are present in
every mental health condition that there is. Now, let's get
back to the mitochondria. They are often known as the
powerhouses of the cell because they create the energy within
the cell, but their rules extend far beyond energy production
(01:35):
and understanding how that influences aging and really provides insights
into how we can maintain our vitality, increase our health span,
and prevent chronic diseases. So what are they? They are
specialized organelles. Organell is just a fancy name for a
substructure of the cell that has one or more and
(01:57):
are one and more clear functions. And so these are
specialized organelles within our cells, and they're responsible for producing ATP.
ATP is the primary energy currency of our cells and
therefore of us, and they achieve this ATP through something
called oxidative phosphorolization.
Speaker 2 (02:21):
So there's going to be a few big words. That's
just a little bit of a warning.
Speaker 1 (02:24):
But that's basically how we convert nutrients from food into energy,
and it's through something called or part of it's through
something called the CREB cycle. So cells with high energy
demands think about neurons in the brain and muscle cells,
they have numerous mitochondria to meet their energy needs. So
(02:45):
the more energy hungry a cell is, the more mitochondria
they tend to have. But they don't just the energy production.
They're also involved in critical processes like calcium signaling, which
is really important for keeping us alive, apoptosis, which is
that programmed sale death that we talked about in previous episodes,
(03:06):
and also the generation of reactive oxygen species. And their
unique feature is that they actually possess their own DNA
called mitochondrial DNA, and it's inherited maternally, so it comes
from the mum and that encodes essential components.
Speaker 2 (03:27):
For their function.
Speaker 1 (03:28):
And this really sets your mitochondria out from everything else,
the fact that they have their own DNA which you
actually get from the mother. And let's talk about mitochondrial
dysfunction and why it's important in aging. So as we
age this, the efficiency of our mitochondria actually declines, and
(03:51):
that leads to reduce the AT production atp sorry production
and increased reactive oxygen species generation. If you remember reaction
of oxygen species, they can create inflammation and all sorts
of nasty things. They basically cause oxidative damage to cellular
components including lipids, proteins in DNA within the cell and
(04:14):
that contributes to cellular senescence and tissue dysfunction. So if
you remember back cellular sinescence, that's like the zombie cells.
So basically, when your mitochondria loser efficiency, we get more
damage inside the cell and the cell turns into zombie cells,
and this decline in mitochondrial function is associated with a
whole host of age related diseases such as metabolic syndrome,
(04:39):
and metabolic syndrome basically increases your risk for a huge
amount of diseases, including cardiovascular disease, the biggest killer, and
we know that in powered mitochondrial function, it disrupts energy metabolism,
contributes to insulin resistance and obesity, which are hallmarks of
metabolic syndrome, but also kind of mitochondrial function and contributes
(05:03):
to neurodegenerative diseases because are neurons, because they're so energy hungry,
they are particularly vulnerable to mitochondrial dysfunction. And we know
now that defective mitochondria can lead to synaptic failure and
the death of neurons, as we see in Alzheimer's disease
(05:24):
and Parkinson's disease. And the other big thing that it
contributes to is cardiovascular diseases. So mitochondal dysfunction in cardiac
cells impers your heart function and contributes to hypertension, atherosclerosis,
and overall cardiovascular disease. And if you take those collectively,
cardiovascular disease neurodegenerate disease and metabolic syndrome, and in the
(05:47):
knock on effects of metabolic syndrome, that actually.
Speaker 2 (05:51):
Accounts for a huge portion of death.
Speaker 1 (05:55):
And that's why I think mitochondrial dysfunction is the most
important hallmark of aging. And we have this theory called
the mitochondrial free radical theory of aging, and that suggests
that a cumulative oxidative damage from these reactive oxygen species
over time leads to the functional decline of our mitochondria
(06:16):
and that drives the aging process. So let's talk about
the stuff that we can actually do. And first up,
of course, is regular physical activity. There is probably nothing
that you can do better for your mitochondria than regular
physical activity.
Speaker 2 (06:34):
Engaging in in.
Speaker 1 (06:35):
Regular exercise is a cornerstone for bolstering mitochondrial health. Physical
activity has been shown over and over again to improve
mitochondrial function and induce mitochondrial biogenesis, which is the creation
of new mitochondria.
Speaker 2 (06:55):
And so it has two things.
Speaker 1 (06:57):
It enhances the efficiency of your existence mitochondria and it
creates new mitochondria. And this adaptation is crucial for meeting
increased energy demands and improving our metabolic health.
Speaker 2 (07:10):
And we know that.
Speaker 1 (07:12):
Both aerobic training, particularly zone two, which is that's that
heart rate of sixty to seventy percent of your max.
But from a non technical perspective, you're exercising, you can talk,
but you can't sing, So you can talk in sentences,
but you're kind of breathing heavily and you can't sing.
(07:33):
If you can sing, you're in zone one. If you
can't talk in sentences, you're in zone three.
Speaker 2 (07:38):
A higher heart rate zone.
Speaker 1 (07:40):
And we know that this zone two, you it's basically
where aerobic metabolism is dominant, and that has been shown
to improve our mitochondrial health, can contribute a little bit
to mitochondria biogenesis. And interestingly, I read a study recently
where they took a bunch of people who weren't fit,
(08:02):
and they put half of them straight into resistance training,
and half of them they did eight weeks of aerobic
training in zone two before they went into resistance training.
Speaker 2 (08:13):
And then they looked at their.
Speaker 1 (08:15):
Strength training gains and muscle sized gains, and it turns
out that the people who'd done the aerobic training first
actually increased their strength and muscle maths quicker than the
people who went straight into the resistance training. And the
thinking is the aerobic training gave them a better functioning
mitochondria and some more mitochondria, and then that translated to
(08:41):
quicker benefits from the strength training. So let's talk about
high physical activity. Actually, oh sorry before we do that.
And high intensity interval training has shown to be very
very potent in stimulating mitochondrial biogenesis of the creation of
new mitochondria. So let's talk about the mechanism. One is AMPK,
(09:04):
and so basically AMPK stimulates mitochondrial biogenesis and enhances oxidative metabolism.
And the other thing, again we're getting a bit giky.
Here is PGC one alpha upregulation and PGC one alpha
If you really want to know what it is, it's
(09:24):
perioxysome proliferator activated receptor gamma coactivator one alpha, and this
is a master regulator of mitochondrial genesis. And this PGC
one alpha pathway is hugely important in our health and
studies have shown as I said, that both aerobic training
(09:46):
and high intensity interval training and resistance training improves our
mitochondrial content and function in our muscle, leading to improved
intinal insensitivity and reduce.
Speaker 2 (09:58):
Risk of metabolic disorder.
Speaker 1 (10:00):
And we also know that fasting and exercise both stimulate
mitochondria biogenesis and stress resistance in muscle cells and through
calcium signaling an AMPK activation.
Speaker 2 (10:14):
Right, that's geeky enough for the minute.
Speaker 1 (10:17):
Let's talk about calorie restriction and intermittent fasting, So reducing
your caloric intake without going into malnutrition or doing implement
intermittent fasting or time restricted feeding as some people call it.
Speaker 2 (10:32):
They have been associated with.
Speaker 1 (10:33):
Enhanced mitochondrial function and increase lifespan in various species, not
in humans, I hasten to add. But the mechanisms by
which this happens is that when we fast, we switch
from burning glucose to burning fat. This what we call
metabolic flexibility. And when you switch over to burning fat,
(10:55):
it actually stimulates the production of ketone bodies like beta
hydrox computury it and that actually serves as an energy
substrate and signaling molecule for the mitochondria. And what fasting
also does is it induces autopogy. I talked about that
in earlier ones. That's the cellular clean up process by
(11:18):
which the things inside the sale actually take damage mitochondria.
This is called mitophagy. And they take that damage mitochondria
and actually recycle them and create new mitochondria. So this
is that's the cellular recycling plant that's actually going on.
And this this is called cyclic metabolic switching theory. It
(11:41):
suggests that health benefits of intermittent fasting may actually be
better than those of continuous calorie restriction. And I actually
think that's a slam dunk because of that interplay between
ketone metabolism, mitochondrial adaptations, and autophogy.
Speaker 2 (11:58):
And I know I'm getting very.
Speaker 1 (11:59):
Geeky here, but I think it's important to understand these processes.
Now I link to this, you'll not be surprised to
hear that if intermittent fasting does this and through ketones,
going on a ktogenic diet where it's it's high fat,
low carbohydrate and moderate protein that stimulates beta hydroxy buttyate
(12:20):
and other ketones which then positively influenced mitochondrial function. And
we see this a katogenic diet really beneficial for Alzheimer's
disease in Parkinson's disease, probably because of the impact that
they have in the mitochondria in brain cells, and the
mechanisms are very similar. Add to intermittent fasting enhance mitochondrial
(12:42):
efficiency because the ktone bodies are really an excellent energy source.
An increase our at B production reduced oxidative stress. But
beta hydroxy butty in itself has actually been shown to
stimulate antioxidant defenses, which is really really important. And a
(13:02):
study combining a ketogenic diet with exercise actually showed that
there were alterations in mitochondrial function, including increased respiratory what's
called respiratory control ratio and ATP production in skeletal muscle,
as well as improvements.
Speaker 2 (13:20):
In metabolic health markers.
Speaker 1 (13:22):
So together with exercise and a ketogenic diet or intermittent
fasting can be very powerful double wami for your mitochondria.
Let's talk about pharmacological or supplement interventions. So NAD precursors
theoretically are good for the mitrochondry because we know NAD
(13:43):
plus is really important. So compounds that you'll see like
NMN plastered all over the internet and NR they are
thought to boost NAD levels. The fact they've been shown
to actually do that, and that's essential for our mag
to chondrial function. But if you don't want to spend
a shitload of.
Speaker 2 (14:02):
Money on NMN and NR.
Speaker 1 (14:05):
You can actually just take some B vitamins because NMN
and NAR are actually converted in the gut to vitamin
B three, which is nicotinic acid. And so you can
either go out and spend a shitload of money on
NMN and NR, or you can just take vitamin B three.
Speaker 2 (14:26):
I know what I would do.
Speaker 1 (14:28):
Another supplement that's pretty promising, And actually I have started
playing with this methylne blue because it has been shown
to actually stimulate the mitochondria through its actions on the
crab cycle. It actually by cut passes for those who
are geeky, complexes one in three in the electron transport
(14:51):
chain and actually stimulates the crab cycle, leading to increased
ATP production and improves cellular energy metabolism through the mitochondria. Okay,
now if that's not kiky enough, let's now talk about
low level light therapy or infrared and near infrared light therapy,
(15:12):
so near infrared light and that's also known as a photobiomodulation.
That is basically applying low level red light to near
infrared light and to stimulate cellular function. And what it
does is it works on something called cytochrome C oxides
(15:36):
and that is a key enzyme in the mitochondrial electron
transport chain. And there is a heap of research now
I that shows that near infrared light actually boosts the
function of your mitochondria, and that is something I was
so convinced by the research. And I have a panel
(15:57):
that does both red light and near in for red light,
because the research for me is very very compelling about
improvements in mitochondrial function. And we are now even seeing
near infrared light helmets of certain way of lengths significantly
improving symptoms in both Parkin's disease and Alzheimer's disease. And
(16:22):
basically what happens is that at light passes goes through
your skeleton and actually stimulates goes it deep inside of
your body and stimulates your mitochondria and certain parts of
the electron transport chain, and that leads to increased energy
(16:43):
production and improves cellular energy metabolism. And the other thing
that near infrared light does is it releases nitric oxide,
and that actually helps to improve blood flow and reduces
oxidative stress.
Speaker 2 (16:57):
And studies have.
Speaker 1 (16:58):
Shown that infrared light penetrates human tissues and benefits mitochondrial
function as I say it, and it can improve things
like mitochondrial dynamics and quality control following ischemia, stroke, cardiac
arras so I actually was using it post my heart
(17:22):
surgery and also for overall brain function, cognitive function. It's
actually been shown to help people recover from straight stroke
and neuro degenerative diseases. So hink conclusion, lots of big mouthfuls,
but basically what we know is our mitochondria are absolutely
(17:45):
key to cellular health and longevity, and doing things like
regular exercising, intermittent fasting, low carbon particularly keathogenic diets, some
potential pharmacology, and near infrared light therapy can all really benefit.
And while studies haven't been established it because they're really
(18:06):
hard to do, I actually think that these things are
additive because they work on slightly different pathways in our mitochondria.
Speaker 2 (18:15):
So I think if.
Speaker 1 (18:16):
You're doing all of them, you're going to get better
benefits than if you're just doing one or two. So
that's it for this week, folks, Catch you next time.
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Intentionally Disturbing
Join me on this podcast as I navigate the murky waters of human behavior, current events, and personal anecdotes through in-depth interviews with incredible people—all served with a generous helping of sarcasm and satire. After years as a forensic and clinical psychologist, I offer a unique interview style and a low tolerance for bullshit, quickly steering conversations toward depth and darkness. I honor the seriousness while also appreciating wit. I’m your guide through the twisted labyrinth of the human psyche, armed with dark humor and biting wit.