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July 12, 2025 37 mins

Welcome back to The Popkin Method, where we cut through the noise to uncover what really works for your health. In today’s episode, host Matthew C. Popkin, M.D. shares an honest, nuanced

Matthew C. Popkin, M.D. explains why weight isn’t just about willpower or the latest diet trend; it’s a complex interplay of biology, hormones, lifestyle, and sometimes, medicine. He emphasizes compassion over shame, sharing insights from his medical practice and breaking down common myths, including the hype around GLP-1 medications like Ozempic and Mounjaro. The episode dives into the pitfalls of quick-fix solutions, the real risks of muscle loss on popular injectable medications, and most importantly, the comprehensive, individualized approach that’s the hallmark of The Popkin Method.

Whether you’ve struggled with weight or simply want to understand the latest treatments and holistic strategies, this episode will help you filter out the fads, get real about sustainable change, and start building a path to better health that doesn’t rely on “magic bullets” just science, support, and a method that actually listens to you.


00:00 Empathetic Weight Loss Physician

05:15 Weight Loss Scams and Real Solutions

09:01 Blood Glucose Regulation Dynamics

09:45 Obesity Drugs Go Beyond Weight Loss

13:08 Muscle Loss from Weight-Loss Medications

17:32 Exercise and Supplements for Muscle Maintenance

21:29 Optimize Hormones for Weight Loss

23:30 "Prioritize Muscle in Weight Loss"

26:53 Holistic, Personalized Weight Management

31:11 Holistic Health Solutions Overview

33:34 Hope Through Holistic Weight Management

36:31 Customized Sustainable Weight Loss Program

41:50 Weight Loss Assistance & Podcast

43:40 "Final Thoughts and Contact"


You can see Dr. Popkin through his online virtual functional medicine program anywhere in the country or the world for that matter.

You can visit Dr. Popkin in his Hollywood Florida office for an in person weight loss experience.

Visit thepopkinmethod.com to send a message to schedule an appointment with Dr. Popkin or email Dr. Popkin at mcpopkinmd@yahoo.com.

Podcast Website - https://thepopkinmethod.com/

Matthew C. Popkin, M.D. - https://thepopkinmethod.com/about

Podcast Partner - TopHealth - https://tophealth.care/

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

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