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June 12, 2025 8 mins

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Welcome back Rounds Table Listeners! Today we're introducing a new format—the first episode in our Trial Files series, where we provide an overview of a recent Trial Files issue. This week, Dr. Mike Fralick discusses three trials included in a recent throwback issue: opioids versus non-opioids for chronic pain; IV albumin for renal impairment and mortality; and omeprazole before endoscopy in patients with GI bleed. Three trials, 9 minutes, here we go!

1. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Trial (00:00 - 2:46)

2. Effect of Intravenous Albumin on Renal Impairment and Mortality in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis (2:47 - 4:50)

3. Omeprazole before Endoscopy in Patients with Gastrointestinal Bleeding (4:51 - 7:39)

What is Trial Files?

  • A free monthly newsletter on practice-changing trials, delivered straight to your inbox-- sign up here! (7:40 - 8:40)

Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods

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