Ep 51: Henry Erlich on DNA Sequencing Technology in 'Genetic Reconstruction of the Past'

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Marty speaks with Dr. Henry Erlich, whose research career gave him a front seat to the development of DNA sequencing technology from its infancy in the 80’s, to the development of forensic applications in the criminal justice system in the 90’s and through to it’s maturity in Next Generation Sequencing methods now used to study evolutionary biology and the deep history of human and hominid evolution. His book is called 'Genetic Reconstruction of the Past - DNA analysis in Forensics and Human Evolution ', and its unifying theme is how we can now use DNA sequencing technology to study historical events, from the recent past in the case of forensic investigation of crimes, to the ancient past in studies of fossil remains to understand the evolution of the human species and the relationships among contemporary and extinct populations.  We talk about the Polymerase Chain Reaction (PCR), detecting sequence and length polymorphism, how DNA tests are used to identify individuals in forensic investigations, how they can be used to track relationships among human populations both ancient and contemporary, and how what we've learned using this technology may help us grow bigger, better, faster brains in our science fictional future.

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