The Stem Cell Podcast

The Stem Cell Podcast

A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

Episodes

ISSCR 2025: Day 4

June 14, 2025 • 28 mins
In June 2025, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Hong Kong, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of four episodes from the meeting. Sessions focused on cell therapy for spinal cord injury, immunocompatible pig organs, and community engagement.
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ISSCR 2025: Day 3

June 13, 2025 • 33 mins
In June 2025, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Hong Kong, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of four episodes, where Daylon and Arun discuss research on cell therapy for inflammatory bowel disease and hearing loss. They also talk about Dr. Jacob Hanna's work on ex utero embryo culture, Dr. Paola Arlotta's ...
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ISSCR 2025: Day 2

June 12, 2025 • 34 mins
In June 2025, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Hong Kong, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of four episodes, where Daylon and Arun cover talks on animal models of regeneration and the public perception of in vitro gametogenesis. They also discuss work on CiPSCs for Type 1 diabetes therapy and growing pi...
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ISSCR 2025: Day 1

June 11, 2025 • 30 mins
In June 2025, Daylon and Arun attended the International Society for Stem Cell Research’s (ISSCR) annual meeting in Hong Kong, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of four episodes, where Daylon and Arun discuss updates from clinical trials for ALS, congenital heart disease, and Parkinson's disease. They also talk about the Presidential Plenary session, chaired by Dr. Valenti...
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Ep. 296: “Cardiovascular Development” Featuring Dr. Maneesha Inamdar

June 10, 2025 • 94 mins
Dr. Maneesha Inamdar is the Director of the Institute for Stem Cell Science and Regenerative Medicine and Professor at Jawaharlal Nehru Centre for Advanced Scientific Research. Her lab uses comparative models, including mice, Drosophila, stem cell lines, and gastruloids, to study developmental biology. She talks about using embryo models to investigate teratogenicity, prioritizing ethnically diverse cell lines, and representing Ind...
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Ep. 295: “Roadmap for Cell Therapy Development” Featuring Drs. Jacqueline Barry, Kapil Bharti, and Jack Mosher

May 27, 2025 • 85 mins
Dr. Jacqueline Barry is the Chief Clinical Officer at Cell and Gene Therapy Catapult, Dr. Kapil Bharti is a Senior Investigator at the National Eye Institute at the National Institutes of Health, and Dr. Jack Mosher is the Scientific Director at the International Society for Stem Cell Research (ISSCR). They discuss their work on the ISSCR's Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies. They...
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Ep. 294: “HSC Development and Regulation” Featuring Dr. Margaret Goodell

May 13, 2025 • 86 mins
Dr. Margaret "Peggy" Goodell is the Vivian L. Smith Chair in Regenerative Medicine and Director of the Stem Cell and Regenerative Medicine Center at Baylor College of Medicine. Her research focuses on HSC regulation and aging. She talks about her discovery of a side population of HSCs, as well as her work on DNMT3A mutation and clonal hematopoiesis of indeterminate potential. Finally, she discusses the rich research environment in ...
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Ep. 293: “Cell Atlases” Featuring Dr. Sarah Teichmann

April 29, 2025 • 91 mins
Drs. Sarah Teichmann is a Member of the Department of Medicine and Professor of Stem Cell Medicine at the Cambridge Stem Cell Institute.  She talks about the plasticity of different cell types and developing whole-organ cell atlases for organs such as the thymus. She also discusses Human Cell Atlas project and overcoming skepticism in its early days. Finally, she talks about integrating computational and wet lab biology, and runnin...
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Ep. 292: “Biomedical Ethics” Featuring Prof. Hank Greely

April 15, 2025 • 88 mins
Professor Hank Greely is the Deane F. and Kate Edelman Johnson Professor of Law and Professor, by courtesy, of Genetics at Stanford University. He is also the Director of the Stanford Center for Law and the Biosciences. He talks about his career path into bioethics and ethical considerations for organoids, bodyoids, and embryo models. He also discusses the potential future of reproduction, including gametogenesis, ectogenesis, and ...
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Ep. 291: “Functional Precision Medicine” Featuring Dr. Scott Younger

April 1, 2025 • 85 mins
Dr. Scott Younger is the Director of Disease Gene Engineering within the Genomic Medicine Center at Children's Mercy Hospital. His research focuses on producing patient-derived cellular models to develop functional precision medicine. He talks about using personalized antisense oligonucleotides to reverse disease phenotypes in organoid models of Duchenne muscular dystrophy. He also discusses his lab's personal connections to the ra...
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Ep. 290: “ISSCR 2025: Illuminating the Future” Featuring Drs. Valentina Greco, Kathryn Cheah, and Eugenia Piddini

March 18, 2025 • 82 mins
Dr. Valentina Greco is the President of the International Society for Stem Cell Research (ISSCR), and Professor of Genetics and Co-Chair of the Status of Women in Medicine at Yale University. Dr. Kathryn Cheah is an ISSCR Program Committee Co-Chair and Emeritus Professor and Chair of Biochemistry at Hong Kong University. Dr. Eugenia Piddini is also an ISSCR Program Committee Co-Chair and Professorial Research Fellow in Cell Biology...
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Ep. 289: “Heart-Forming Organoids” Featuring Dr. Robert Zweigerdt

March 4, 2025 • 86 mins
Dr. Robert Zweigerdt is a Principal Investigator at Hannover Medical School, where his lab focuses on cardiac differentiation and the scalable culture of PSCs. He talks about regulating the lineage-specific differentiation of hPSCs and generating heart-forming organoids that mirror developmental cardiogenesis. He also discusses the importance of mentorship and the benefits of an international research group.
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Ep. 288: “Cerebellar Organoids” Featuring Dr. Giorgia Quadrato

February 18, 2025 • 82 mins
Dr. Giorgia Quadrato is Assistant Professor of Stem Cell and Regenerative Medicine at the University of Southern California. Her research focuses on brain developmental and neural organoids. She talks about protocols for generating cerebellar organoids, including those with functional Purkinje cells. She also discusses a transcriptomic atlas of neural organoids and the stem cell research landscape in California.
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Ep. 287: “Blood Development” Featuring Drs. Andrew Elefanty and Elizabeth Ng

February 4, 2025 • 89 mins
Drs. Andrew Elefanty and Elizabeth Ng are Senior Principal Investigator and Principal Investigator, respectively, at the Murdoch Children's Research Institute. In the Blood Development group, they aim to develop innovative cellular therapies for blood and  cartilage-related diseases. They talk about their recent study deriving and transplanting HSCs, their work on reporter lines, and their collaborative lab setup.
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Ep. 286: “Neural Lineage Identity” Featuring Dr. Marius Wernig

January 21, 2025 • 84 mins
Dr. Marius Wernig is a Professor of Pathology and a Co-Director of the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University, where his research interests include direct reprogramming and neurological disease modeling. He talks about his early work reprogramming neuronal cells from fibroblasts, adopting iPSCs, and growing his lab. He also discusses his recent research on cell therapy for brain and skin di...
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Ep. 285: “Funding the Future” Featuring Dr. Jonathan Thomas

January 7, 2025 • 91 mins
Guest: Dr. Jonathan Thomas "JT" is the President and CEO of the California Institute for Regenerative Medicine (CIRM), an organization that provides funding for stem cell research with the purpose of accelerating treatments for patients in need. He talks about working to ensure diversity in clinical trials and developing treatments that are affordable and accessible to patients. He also discusses the progress during the twenty year...
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Ep. 284: “Organ Chip Engineering” Featuring Dr. Milica Radisic

December 10, 2024 • 82 mins
Dr. Milica Radisic is a Professor and Canada Research Chair at the University of Toronto. Her lab uses organ-on-a-chip engineering to mimic physiology of the heart, kidney, and vasculature for the purpose of modeling human disease and discovering more effective drugs. In this episode, she talks about the challenges of studying the heart and strategies to mature cardiomyocytes. She also discusses using macrophages to vascularize hea...
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Ep. 283: “Molecular Hematopoiesis” Featuring Dr. Cynthia Dunbar

December 3, 2024 • 90 mins
Dr. Cynthia "Cindy" Dunbar is National Institutes of Health (NIH) Distinguished Investigator and Chief of the Translational Stem Cell Biology Branch at the National Heart, Lung, and Blood Institute of the NIH. She talks about using macaques to study hematopoiesis and aging, and the challenges and considerations for using these models. She also discusses her collaborative study transplanting iPSC-derived cardiomyocytes into rhesus m...
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Ep. 282: “Whole-Body Regeneration” Featuring Dr. Mansi Srivastava

November 26, 2024 • 94 mins
Dr. Mansi Srivastava is Professor of Organismic and Evolutionary Biology at Harvard University and Curator of Invertebrate Zoology at the Harvard Museum of Comparative Zoology. Her lab uses distantly related species to study evolution and regeneration. She talks about establishing Hofstenia miamia, or the three-banded panther worm, as a model system. She also discusses her lab's work on adult stem cell lineage tracing and whole-bod...
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Ep. 281: “Fertility Treatments” Featuring Drs. Dina Radenkovic and Bruna Paulsen

November 12, 2024 • 89 mins
Drs. Dina Radenkovic and Bruna Paulsen are Co-Founder & CEO and VP of Manufacturing and Therapeutic development at Gameto, a biotech company developing treatment solutions to improve women's reproductive health. Their lead platform, Fertilo, uses ovarian support cells to mature oocytes outside of the body with the goal of making IVF and egg freezing shorter, safer, and more effective.
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