The Trip Lab

The Trip Lab

The Trip Lab is a podcast on integrative medicine and psychedelics hosted by board-certified physician Dr. Mary Ella Wood. Through conversations on psychedelics, neuroscience, and whole-person care, the show examines emerging evidence alongside deeper questions of meaning, healing, and human experience. Life is a trip. Let’s explore it.

Episodes

June 15, 2026 34 mins

In Part 4 of Detox in a Toxic World, we take an evidence-based look at detox supplements, cleanses, binders, protocols, and some of the most common products being sold in the name of detox. From milk thistle, NAC, glutathione, and sulforaphane to activated charcoal, clay binders, detox teas, colon cleanses, and coffee enemas, this episode breaks down what may actually be supportive, what has limited evidence, and what may be harmfu...

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In Part 3 of Detox in a Toxic World, we take a closer look at what “detox” actually means and how the body is already doing it every single day. This episode breaks down the body’s major detox and elimination pathways, including the liver, gut, kidneys, lungs, skin, lymphatic system, and glymphatic system, and explains how these beautifully coordinated processes help clear hormones, waste products, and environment...

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In Part 2 of Detox in a Toxic World, we move from understanding the problem to actually doing something about it. This episode is all about reducing exposures to toxins, starting in the place where many of us have the most control: the home. We explore the idea of the home as a health ecosystem and walk through practical ways to lower your total toxic burden without falling into fear, perfectionism, or overwhelm.

We cover simple low...

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Today we’re kicking off a new series, Detox in a Toxic World, with a deep dive into environmental toxins and their impact on health. In this episode, we break down what environmental toxins actually are, how they affect the body, and why this topic is both real and often wildly misunderstood. We walk through the major categories of toxins in modern life, including microplastics, pesticides, mycotoxins, heavy metals, food addi...

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Longevity medicine is one of the most exciting frontiers in modern healthcare. With new technology, more advanced biomarker testing, deeper aging research, and emerging interventions that aim to help us better understand and potentially shape the biology of aging, the field is opening up an entirely new level of conversation about healthspan, vitality, and the future of medicine.

Today, we dive deeper into the roots of longevity med...

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Women’s health is often approached through a hormonal lens, but hormones are only one part of the story. In this episode, we explore a broader framework for women’s health that includes the neuro-endocrine system, inflammation, metabolism, the gut, autoimmunity, and the mind-body connection. We talk about PMDD, perimenopause, PCOS, endometriosis, IBS, autoimmune disease and why so many conditions that affect women are b...

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The modern psychedelic renaissance is teaching us something important, not just about psychedelic substances, but about how healing actually happens. Beyond the molecules, psychedelic science is revealing the conditions under which the human nervous system becomes capable of change.

This episode explores the idea that psychedelics have long functioned as teachers, not only through ingestion, but by showing us how context, meaning, a...

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Psychedelic medicine is moving fast. Faster than regulation. Faster than standardization. And in many ways, faster than the data itself.

In this episode, we explore what psychedelics are teaching us about practicing medicine under uncertainty. From the rapid rise of training programs and self-identified experts, to the tension between lived experience, emerging science, and clinical responsibility, this conversation looks beyond hyp...

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Our understanding of how psychedelics work has evolved in meaningful ways over the past several years. While earlier neuroscience frameworks helped move the field forward, newer research has added important nuance and depth to how we interpret brain imaging, network behavior, and subjective experience.

In this episode of The Trip Lab, I offer a refresh on psychedelic neuroscience, focusing on key updates from the past four years and...

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Microdosing has gone mainstream and is often described as a tool for creativity, mood, productivity, and emotional healing. But what does the science actually say?

In this episode of The Trip Lab, I take an evidence-based look at microdosing psychedelics. We explore what microdosing is, how it differs from full-dose psychedelic therapy, and the proposed neurobiological mechanisms that have been suggested in the literature. I review ...

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Functional medicine testing is everywhere. It is often marketed as “test, don’t guess,” and just as often dismissed as invalidated or unscientific. So what is the truth?

In this episode of The Trip Lab, we take a deep dive into what functional medicine testing actually is, how it differs from traditional laboratory testing, and what clinicians really mean when they say these tests are not “validated.” W...

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Is modern medicine still evidence-based, or have we quietly mistaken rigor for certainty?

Evidence-based medicine is essential. It’s why we save lives, advance care, and trust modern healthcare. But as medicine has become more specialized and disease more complex, something subtle has happened. Rigor has increasingly turned into reductionism, and evidence is often applied in ways that don’t fully match the realities of c...

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Why do psychedelic experiences so often feel spiritual, sacred, or life-changing? Why are mystical-type experiences so closely linked to lasting therapeutic benefit? And why does medicine struggle to talk about them at all?

In this episode, we explore the neuroscience and psychology behind mystical experiences in psychedelics. We examine how shifts in brain networks involved in meaning, identity, and self-referential thinking can gi...

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NAD has become one of the most talked-about molecules in longevity medicine—showing up in supplements, IV clinics, lab testing, and bold claims about aging and healthspan. But what does the science actually show?

In this episode of The Trip Lab, we take a clear, evidence-based look at NAD and use it as a lens to explore the broader field of longevity medicine. We break down what NAD does in the human body, why it’s linke...

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In this Deep Dive episode of The Trip Lab, we unpack hyperlipidemia (high cholesterol) beyond the oversimplified “LDL bad, HDL good” narrative. We also take a clear-eyed look at the most common concerns people have about statins, what the evidence actually shows, and where these medications fit—and don’t fit—within a thoughtful, individualized approach to cardiovascular risk.

From there, we explore inte...

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In this season 2 opening episode of The Trip Lab, I return from maternity leave with a deeply personal exploration of how psychedelic experiences mirror one of the most profound transitions in a woman’s life: motherhood.

From the sudden crash of postpartum hormones to the full dissolution of identity and the slow reconstruction of self, I reflect on how becoming a mother felt strikingly similar to a psychedelic journey —...

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Osteopathic manipulative treatment (OMT) is a hands on diagnostic and treatment modality that DOs learn in medical school. You may have seen the DO (rather than MD) after your doctor's name and never really understood what that meant. We dive into the difference between MDs and DOs and talk all about what osteopathic medicine is in this episode.

Many OMT treatments actually mirror what a yoga practice can do for you as well...

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August 8, 2023 31 mins

In this episode we will take a deep dive into one of the leading causes of the global burden of disease-- hypertension, or high blood pressure. We will go over the pathophysiology, learn how hypertension develops and why it is so bad for the body. 

After understanding the root causes, we can then better understand how our traditional pharmaceuticals, lifestyle interventions, and holistic integrative therapies work to tr...

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Today I will be introducing a new 'deep dive series' on The Trip Lab. We are going to be looking into the most common medical conditions to really understand what is happening in the body and how they develop. With that understanding, we can better understand how our treatments work-- including pharmaceuticals and surgery as well as integrative therapies like herbal medicine and mind-body medicine. 

To start this series...

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This episode is going to be a high level overview over all of the primary causes of anxiety and depression, and integrative approaches to treat them.

Anxiety and depression is a lot more complicated than just writing a script for sertraline or recommending therapy. These disorders definitely have a psychological component that can stem from chemical imbalances in the brain... but other causes include nutritional deficiencie...

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