Melding quantum mechanics with artificial intelligence is going to change how we understand our world.

Several years ago, a small team was pursuing a deeper understanding of the quantum sciences while tracking advancements in machine intelligence. Combining two complex and misunderstood fields of study, Fernando Dominguez Pinuaga, Vice President, and his colleagues formed SandboxAQ, a growing juggernaut in materials discovery, cyber...

Where is the money in oceanographic research?

Fundamental understanding of the watery parts of our planet (i.e. most of it) is woefully under pursued. However, just as it seems some ocean systems are almost falling apart – coral bleaching, rising tides, species extinctions – we are beginning to see more attention paid to exploring the depths.

"There will be unicorns of the ocean, very successful companies w...

It’s a bird, it’s a plane, it’s… technically a flying boat! 
When challenged to imagine how to electrify aviation, Billy Thalheimer, CEO and co-founder of REGENT Craft, and his team set to work looking at what has been done with hydroplanes before – and what emerging technologies are available today that change the equation for what is possible and economically achievable.

“Building with atoms is harder than building with bits. ...

The blue parts of our planet are beautiful yet stunningly punishing for even our toughest of technologies.

Dark, crushing, unexplored, and unknown – the depths of the seas are where an explorer like Jeff Smith has devoted his career to understanding. As the Vice President and General Manager of Autonomous and Undersea Systems at Saab, Inc., Smith has experience developing submersibles of nearly every shape and size, including s...

Tough Tech Today is transitioning seasons, recapping our Season 3 themes exploring the tough tech domains of biology, space, and fusion energy. We are also preparing for the show's fourth season and we are really excited for it!

Upcoming themes:

• Blue tech – The advanced technologies of the maritime industry. Incredible machines, sustainable oceans, and mysteries to solve in our planet's seas.
• Quantum sciences – A wild wo...

If this company perfectly combines lasers and atoms, the reaction could be worth trillions of dollars.

Focused Energy’s Thomas Forner, CEO, and Pravesh Patel, CTO, join us to talk about making lasers. Lots and lots of lasers. But for what aim? They are pointing hundreds of directed beams at a tiny target: a millimeter-sized plastic capsule of deuterium and tritium, about the size of a peppercorn. These experiments may reveal a comme...

Investors are betting big on clean energy becoming the norm.

Tina Tosukhowong of TDK Ventures joins us for a review of the major approaches to curbing carbon emissions in hard-to-abate industries. A thorough assessment led Tosukhowong to opportunities for practical, grid-scale fusion. TDK Ventures invested in Type One Energy Group, a private fusion company affiliated with the University of Wisconsin-Madison. Their stellarator-based ...

How do we harness the power of the stars to deliver clean energy on Earth?

It has been a collective goal – and, perhaps, an impending imperative – for human civilization to secure renewable energy sources for its present and future needs. The team at Proxima Fusion (https://www.proximafusion.com/about), led by co-founder and CEO Francesco Sciortino (https://www.linkedin.com/in/francesco-sciortino-aa340180/), is focused on one a...

Standing up a space force within the world’s largest bureaucracy is not for the faint of heart.

Preston Dunlap – former (and first) Chief Architect / Chief Technology Officer of the United States Air Force and Space Force and present CEO of Arkenstone Ventures – has developed a privileged view into the government machinations necessary to design, develop, and buy the right mix of tough tech capabilities. Mission-focused an...

An early-stage startup will offer unparalleled weather data when it unfolds its orbital sensors.

Captivated by the stars and focused on improving life on Earth, Mithril Technologies founder and CEO, Scarlett Koller, is venturing into weather awareness and storm tracking by launching and commercializing a large space-based sensor. In this episode, we have the privilege of learning how Koller and her co-founder are translating a new t...

In one sentence: The space economy is booming in more ways than one.
Space-based assets are changing the way industries operate on Earth. Chad Anderson – Founder and Managing Partner at Space Capital – is one of those individuals who has a deep perspective on the what it is like backing the entrepreneurs who are launching the newest breed of space companies.
An investor by profession and explorer by passion, Anderson relate...

In one sentence... The interactions of the microbial world within us has been incredibly difficult to see – until now.

From the depths of our intestines to the surface of our skin, our bodies are host to trillions of microbial cells spanning thousands of species. While critical to helping us to fend off illnesses and digest complex foods, we know very little about the complex interactions among these microbes.

The team at Concerto Bi...

In one sentence...

Aging is malleable and there is a particular, mysterious protein of interest that may enable new therapies for age-related diseases such as stroke, diabetes, and obesity.

Young blood in old bodies has been demonstrated in several studies to counteract some age-correlated ailments. Mark Allen, a medical doctor by training and an entrepreneur in practice, co-founded Elevian to understand and commer...

In one sentence...

Overview