Good news for dogs with demodex & MDR1- mutation: Isoxazolines vs. ivermectin | Twin Trees Vet Talk

On today's episode of Twin Trees Vet Talk, we welcome our very special guest, Dr. Vincent Defalque. Dr. Defalque is a Board Certified Veterinary Dermatologist in Vancouver, BC (Canada). We hear about a 6 month old Australian Shepherd puppy named Kenny that Dr. Defalque saw for a severe skin disease caused by demodex, a mite that lives in the hair follicle (this disease is often called demodectic mange or demodecosis). The classic treatment usually takes an average of 10 weeks with daily oral ivermectin, and the disease can be notoriously difficult to treat. Because ivermectin is not safe to use in all dogs (Australian shepherds, collies and several other breeds often have a genetic mutation that causes them to become very sick or even die if given ivermectin), Dr. Defalque used a new class of drugs called Isoxazolines off-label to help this puppy. And it worked!

We hope you enjoy this episode! Please leave your questions and comments below!

FULL BLOG POST: https://twintreesvet.com/blogs/vet-talk/good-news-for-dogs-with-demodex-and-mdr1-mutation-collies-shepherds-etc-isoxazolines-instead-of-ivermectin-for-parasitic-diseases-twin-trees-vet-talk-podcast

P.S. I just want to add a quick apology to Dr. Defalque for taking more than a year from the time of our interview to finally edit and publish this episode (my excuses: busy life, chronic computer problems, and general burnout/ aversion of the veterinary profession). I appreciate so much you taking the time to share your knowledge and expertise!

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#pethealth #demodex #mange #australianshepherddogs #pets #veterinaria #doghealth

About Dr. Vincent Defalque, DVACD:

Following graduation from the University of Liege (Belgium), Dr. Defalque completed an internship at Vet’Agro Sup (France), then a dermatology residency at Michigan State University. He became a board certified veterinary dermatologist in 2006. Dr. Defalque is a Past-President of the Canadian Academy of Veterinary Dermatology, and currently serves as the Canadian representative at the World Association for Veterinary Dermatology. Dr. Defalque works at North West Veterinary Dermatology Services in Vancouver, BC and St. Albert, AB. His special interests include the diagnosis and management of ear diseases in dogs and cats as well as feline dermatology.