Web3 with Sam Kamani

Web3 with Sam Kamani

"Web 3.0 with Sam Kamani" is all about Web 3 and how it is going to change the world. If you are interested in learning more about the 4th Industrial revolution then this podcast is for you. Web 3.0 or Web 3 is often hailed as the technology that will usher in the 4th industrial revolution. This revolution is going to affect every industry, business, government and person on this planet. Web 3.0 is a collection of technologies that are going to change how we collaborate with each other and interact with our environment. Let's uncover the opportunities and risks of the new version of Web.

Episodes

December 15, 2025 32 mins

L1 blockchains have gone through every hype cycle: ICOs, NFTs, gaming, metaverse, now AI. But what actually survives?

In this episode, I speak with Alexander Zahnd, CEO of Zilliqa, an L1 that launched in 2017 and recently became fully EVM-compatible. Alex shares his journey from a decade in Swiss TradFi and treasury/regulatory projects into DeFi, and how that shaped his views on financial rigor, regulation and long-term blockchain a...

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AI demand for GPUs is exploding – and most of that capacity is locked inside underused data centers.

In this episode, I talk with Mark from Aethir, a decentralized GPU cloud that aggregates idle, enterprise-grade GPUs into a global network. We discuss how Aethir feels like AWS on the front end but works like “Airbnb for data centers” behind the scenes, why compute demand outpaces supply, and how they keep latency low across 90+ coun...

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Bitcoin isn’t just something you buy and hold anymore – it can be an engine for a real on-chain economy.

In this episode, I’m joined by Hunter from Terahash, a true crypto OG with a decade in the industry and a past life as Justin Sun’s right hand on ecosystem development at Tron. We talk about his journey from Oculus and VR to traveling the world for Tron, seeing firsthand how stablecoins and Bitcoin are helping people escape infla...

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In this episode I talk with Wes from Technotainment, who’s building what he calls Streaming 2.0 — a new model for Hollywood that combines content, community, and commerce, powered by Web3 and AI.

We break down why the traditional subscription/ads model is failing in an infinite-content world, how micro-casting lets each show own its audience and revenue, and how tokens can route value directly between advertisers, creators, and fans...

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In this episode, I sit down with Giel from kpk (formerly karpatkey) live at Devconnect Buenos Aires. KPK has quietly managed billions for major DAOs such as ENS, DYDX, Arbitrum, and Balancer — operating with an institutional-grade risk framework while staying fully non-custodial.

We talk about institutional adoption heading into 2025–2026, why traditional funds and family offices now want safer access to DeFi yields, how risk curati...

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In this episode, I speak with Marcos from Parfin/Rayls, live at Devconnect Buenos Aires, where their new finance-focused L1 is already seeing explosive use: 30K wallets in 24 hours, 3M+ transactions, and 800K addresses on testnet.

We discuss how stablecoins are shifting from crypto-native tools to bank-issued, institution-grade payment rails, why Brazil now has several sovereign stablecoins, and why U.S. banks may soon launch their ...

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In this episode, I speak with Xin from Sign Global, a company building sovereign blockchain infrastructure for governments — from national stablecoins and CBDCs to digital identity and real-world asset systems.

Xin explains why crypto struggles to reach real adoption: we build great tech but rarely solve problems for banks, regulators, or everyday users. Sign Global works directly with governments to modernize payments, identity, an...

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In this episode, I sit down with Wojciech Kaszycki — serial entrepreneur, business angel behind 19+ ventures, and the mind behind both Mobilium and BTCS.

Wojciech shares how he went from building one of Poland’s earliest e‑commerce platforms to pioneering fintech and crypto infrastructure. We explore why his teams focus on building real, regulated bridges between traditional finance and digital assets — not just hype.

We dig into how...

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Ismael (Founder/CEO) and Nate (Defense GTM) from Lagrange explain why the biggest commercial demand for cutting-edge cryptography might be outside crypto—securing AI in defense, healthcare, and regulated finance. We cover: why they built DeepProof (a zero-knowledge ML library that proves model outputs over private inputs), how this fits the DoD’s zero-trust mandates, and why frontier crypto R&D should serve national interest, n...

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I sat down with Michael Sena to explore how we’ll start trusting AI agents with real‑world responsibilities — from crypto trading to enterprise workflows. We talk about his Web3 roots, the genesis of the concept behind skill markets, and how his project is creating transparency and performance benchmarks in a rapidly evolving AI ecosystem. If you’ve ever wondered how to evaluate an agent, give one control of money, or build one you...

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In this episode I sit down with Ivan, the newly appointed CEO of Neon Labs, a serial‑founder with six exits and a deep background in infrastructure, distributed systems and Web3. We explore how Neon Labs is tackling the challenge of running an EVM on Solana, what “network extensions” mean and why this matters for builders, founders and the entire ecosystem. 

We also dig into tokenization, open‑source business models and where the in...

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In this episode I sit down with Zain Zaidi, co‑founder and CEO of TransCrypts, to explore his personal story and the mission driving his startup. He shares how a misplaced grad‑school transcript sparked a blockchain solution for identity verification, how his company now serves millions of users and hundreds of enterprises, and why the deepfake era makes what they do more critical than ever. We dive into the tech, the regulatory hu...

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In this episode I chat with Ian Brunner, co‑founder and CEO of IPTS - Interplanetary Talent Services, about how recruiting in Web3 and AI safety is changing — and how founders and job‑seekers alike can win. Ian shares how he pivoted from ad‑tech and Facebook into Web3, helped build recruiting at Protocol Labs, then spun out to form IPTS and now supports over a hundred companies placing talent across complex, frontier tech roles. We...

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In this episode I chat with Alex (CMO) and Andrew (CPO) of Sticker Pack about how they’re turning something as simple as a sticker on Telegram into a Web3‑community powerhouse. We trace their journeys back to early crypto days, uncover how they saw the gaps in traditional NFTs, and why they believe Telegram’s built‑in ecosystem offers a unique route for mass adoption. The podcast dives into what drives Sticker Pack’s growth, how th...

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In this episode I sit down with Grigore Roșu (Grigore Rosu), former NASA researcher and computer‑science professor, now building the Pi Squared Network. We dive into what Web3 really means (hint: it isn’t just blockchains). Grigore explains why the conventional blockchain model is inefficient, how his team is creating a parallel settlement network that scales, and what this could mean for everything from payments to gaming to AI‑ag...

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I sat down with Toby  Gilbert, co‑founder of Pact Swap, to dig into how he went from years in telecoms to building infrastructure for the Web3 era. We talk about the problems in decentralized exchanges, why cross‑chain and native Bitcoin support matter, and how Pact Swap is positioning itself to offer DEX functionality at central‑exchange price levels — without KYC and heavy overheads. If you’ve ever wondered how innovation in DEX ...

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Imagine owning your own AI. That’s exactly what David Johnston, core contributor at Morpheus believes is not just possible, but inevitable. In this episode, we go deep on smart agents, how they’re the next evolution after smart contracts, and why decentralized AI will reshape how we use intelligence. David shares why the world has now officially crossed the line where AI has more brainpower than all humans combined,and what that me...

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Imagine a world where your kids learn directly from Einstein in the metaverse. That’s the bold vision Mete Al is building at ICB Labs.

In this episode, I sat down with Mete live at Token2049 in Singapore to explore how ICB Labs is fusing AI, blockchain, and immersive metaverse experiences to reshape education. From building a global network of university partnerships to creating age-appropriate AI mentors for kids, Mete shares how h...

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Catherine (Space and Time) breaks down why blockchains alone can’t power complex apps—and how a verifiable, decentralized database with ZK proofs closes the gap for enterprises, devs, and AI agents. We cover: what SxT is, how its patented ZK approach offloads compute to a single node and proves correctness on-chain, why institutional adoption is sticky, and marketing tactics that actually work in Web3 (what to outsource vs keep in-...

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What if your digital identity could unlock payments, access, and compliance—all without giving up your privacy?

In this episode, I talk to Boris, CEO of Concordium and former co-founder of Copper, one of the biggest institutional custodians in crypto. We dive deep into why Concordium is building a new Layer 1 focused on privacy, programmable payments, stablecoins, and compliance-first infrastructure.

Boris shares insights on the chal...

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