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August 27, 2025 17 mins

Welcome back to What The Gut, hosted by Allison, a double board-certified family nurse practitioner specializing in functional medicine. In this episode, we dive deep into the rising star of functional medicine: Low Dose Naltrexone (LDN). Discover how LDN, a game-changer for chronic inflammation, autoimmune diseases, and gut issues, works by blocking opioid receptors and boosting endorphins. Learn who can benefit from LDN, its role in regulating the immune system, reducing inflammation, and its usage in various conditions including IBS, Crohn's disease, and fibromyalgia. We also address common side effects, best practices for usage, and why it’s not widely prescribed by conventional doctors. Tune in for expert insights, practical strategies, and how to discuss LDN with your healthcare provider. Stay informed, take control of your health, and thrive with functional medicine.

 

00:00 Introduction to What The Gut Podcast

01:26 Exploring Low Dose Naltrexone (LDN)

02:02 How LDN Works and Its Benefits

03:03 LDN for Gut Health and Autoimmunity

04:06 Who Can Benefit from LDN?

05:25 Using LDN: Dosage and Side Effects

10:40 Challenges in Prescribing LDN

15:30 Conclusion and Next Steps

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🎙️Show Notes and Resources

 

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