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July 21, 2025 50 mins

Could the key to protecting women's brains during menopause already exist and be overlooked for decades?

In this groundbreaking episode, I sit down with Dr. Rhonda Voskuhl, UCLA neurologist and internationally recognized researcher, to explore the powerful link between estrogen, menopause, and cognitive health. Dr. Voskuhl breaks down her decades of research on sex differences in neurological disease and the role of estriol, a lesser-known estrogen unique to pregnancy, in protecting brain function.

We discuss:

  • Why 70% of menopausal women experience cognitive decline and how it’s often dismissed

  • The overlooked role of estriol in brain protection and how it differs from estradiol

  • Her creation of Cleopatra RX and the science behind its formulation for cognition, not just hot flashes

  • What her clinical trials in MS patients revealed about estrogen’s neuroprotective effects

  • The future of menopause care, Alzheimer’s prevention, and women’s brain health

  • The difference between FDA approval, safety data, and why estriol has been used safely in Europe for 40+ years

Dr. Voskuhl shares why she believes we must stop ignoring the brain in menopause and how Cleopatra RX is aiming to fill that gap with a safe, affordable, and research-backed solution for cognitive decline in midlife women.

This is a must-listen for any woman experiencing brain fog, verbal memory lapses, or focus issues during perimenopause and menopause.

🔗 Resources & Links:

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Disclaimer  

This podcast is for entertainment, educational, and informational purposes only. The hosts, guests, and experts featured are not your personal healthcare providers or advisors. The content should not be considered as professional, personalized medical, psychological, or prescriptive advice.  

Always consult qualified professionals such as your physician, therapist, pharmacist, or coach for specific concerns and decisions related to your health or lifestyle. *Women Mastering Midlife* is not responsible for any undesired outcomes resulting from actions taken based on the content of this podcast.  


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