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April 6, 2025 25 mins

Dave Lee returns to break down one of the most misunderstood hormones in men’s health: pregnenolone. From its critical role in brain health and neurotransmission to its connection with hormone replacement therapy, Dave shares his personal journey recovering from a traumatic brain injury and how pregnenolone played a key role in his recovery.

He discusses why pregnenolone is often overlooked, how it functions as more than just a precursor hormone, and why it can be life-changing—but only for the right patient. Dave also dives into the risks of supplementing blindly, explains why some men on TRT still feel terrible, and gives crucial insight into the role of pregnenolone in cognitive health, stress response, and overall hormonal balance.

 

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Disclaimer: The Women Want Strong Men Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional healthcare services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment.

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