All Episodes

September 2, 2025 89 mins

The germ theory of disease is one of the greatest breakthroughs in human history. But it took more than 2,000 years of false starts and resistance before medicine finally recognized that germs cause disease. In his book Germ Theory, Dr. Robert Gaynes unpacks why this shift was so hard to achieve. In this episode, he and Dart explore what it teaches us about paradigm shifts today: why new ideas face such resistance, how the personalities of innovators influence acceptance, and what happens when a powerful new paradigm leads us to overcorrect.

Dr. Robert P. Gaynes is an infectious disease physician and Professor of Medicine at Emory University. He is the author of Germ Theory, a CHOICE Outstanding Academic Title.

In this episode, Dart and Robert discuss:
- Why it took centuries to accept that germs cause disease
- What resistance to handwashing reveals about change
- Breakthroughs Robert witnessed in his career
- How medicine’s history reveals patterns of change
- HIV’s transformation from fatal to treatable
- What happens when new paradigms go too far
- How personality shapes whether innovations are accepted
- Lessons for anyone driving change at work today
- And other topics…

Dr. Robert P. Gaynes is an infectious disease physician and Professor of Medicine at Emory University. He chairs Emory’s Infection Control and Antimicrobial Stewardship Committees, attends at the Atlanta VA Medical Center, and has written extensively on hospital-acquired infections and antimicrobial use. He is the author of Germ Theory: Medical Pioneers in Infectious Disease, named a CHOICE Outstanding Academic Title.

Resources Mentioned:
Germ Theory: Medical Pioneers in Infectious Disease by Robert Gaynes: https://www.amazon.com/Germ-Theory-Pioneers-Infectious-Diseases/dp/168367376X
Get discounted tickets to the Responsive Conference, featuring past Work for Humans guests Bree Groff and Simone Stolzoff – September 17–18, Oakland, CA. Use code “11fold”: https://www.responsiveconference.com/tickets
Register to attend the UWEBC Conference, where Dart keynotes the HR track alongside Ethan Mollick and Nancy Giordano – September 30, University of Wisconsin: https://uwebc.wisc.edu/conference/registration/

Connect with Robert:
LinkedIn: https://www.linkedin.com/in/robert-p-gaynes-49b1541/

Work with Dart:
Dart is the CEO and co-founder of the work design firm 11fold. Build work that makes employees feel alive, connected to their work, and focused on what’s most important to the business. Book a call at 11fold.com.

Mark as Played

Advertise With Us

Popular Podcasts

On Purpose with Jay Shetty

On Purpose with Jay Shetty

I’m Jay Shetty host of On Purpose the worlds #1 Mental Health podcast and I’m so grateful you found us. I started this podcast 5 years ago to invite you into conversations and workshops that are designed to help make you happier, healthier and more healed. I believe that when you (yes you) feel seen, heard and understood you’re able to deal with relationship struggles, work challenges and life’s ups and downs with more ease and grace. I interview experts, celebrities, thought leaders and athletes so that we can grow our mindset, build better habits and uncover a side of them we’ve never seen before. New episodes every Monday and Friday. Your support means the world to me and I don’t take it for granted — click the follow button and leave a review to help us spread the love with On Purpose. I can’t wait for you to listen to your first or 500th episode!

Ruthie's Table 4

Ruthie's Table 4

For more than 30 years The River Cafe in London, has been the home-from-home of artists, architects, designers, actors, collectors, writers, activists, and politicians. Michael Caine, Glenn Close, JJ Abrams, Steve McQueen, Victoria and David Beckham, and Lily Allen, are just some of the people who love to call The River Cafe home. On River Cafe Table 4, Rogers sits down with her customers—who have become friends—to talk about food memories. Table 4 explores how food impacts every aspect of our lives. “Foods is politics, food is cultural, food is how you express love, food is about your heritage, it defines who you and who you want to be,” says Rogers. Each week, Rogers invites her guest to reminisce about family suppers and first dates, what they cook, how they eat when performing, the restaurants they choose, and what food they seek when they need comfort. And to punctuate each episode of Table 4, guests such as Ralph Fiennes, Emily Blunt, and Alfonso Cuarón, read their favourite recipe from one of the best-selling River Cafe cookbooks. Table 4 itself, is situated near The River Cafe’s open kitchen, close to the bright pink wood-fired oven and next to the glossy yellow pass, where Ruthie oversees the restaurant. You are invited to take a seat at this intimate table and join the conversation. For more information, recipes, and ingredients, go to https://shoptherivercafe.co.uk/ Web: https://rivercafe.co.uk/ Instagram: www.instagram.com/therivercafelondon/ Facebook: https://en-gb.facebook.com/therivercafelondon/ For more podcasts from iHeartRadio, visit the iheartradio app, apple podcasts, or wherever you listen to your favorite shows. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

The Joe Rogan Experience

The Joe Rogan Experience

The official podcast of comedian Joe Rogan.

Music, radio and podcasts, all free. Listen online or download the iHeart App.

Connect

© 2025 iHeartMedia, Inc.