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October 15, 2025 38 mins

In this week’s episode of the Xtalks Life Science Podcast, host Ayesha Rashid, Senior Life Science Journalist at Xtalks.com, spoke with Juan Domínguez-Bendala, PhD, Director of Stem Cell and Pancreatic Regeneration Programs, Diabetes Research Institute (DRI) at the University of Miami, to discuss his research team’s new research published in Nature Communications that could redefine diabetes treatment.

Dr. Domínguez-Bendala team’s study reveals how THR-123, a small peptide, can trigger the regeneration of insulin-producing beta cells in the pancreas, effectively restoring normal blood sugar levels in preclinical models. The discovery opens the door to a potential new class of regenerative therapies for insulin-dependent diabetes, offering hope for millions of patients worldwide.

Dr. Domínguez-Bendala’s scientific journey includes a PhD he earned under Dr. Jim McWhir, co-creator of Dolly the sheep, to pioneering research in human embryonic stem cells at the University of Miami’s Diabetes Research Institute, where he now leads his own lab and chairs the university’s Embryonic Stem Cell Research Oversight (ESCRO) Committee.

Tune in to hear how Dr. Domínguez-Bendala’s team’s findings could change the way we think about diabetes and the promise of teaching the pancreas to heal itself.

For more life science and medical device content, visit the Xtalks Vitals homepage. https://xtalks.com/vitals/

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