What's My Age Again?

There’s a new take on things for this episode as Katherine welcomes Tim Spector onto the podcast – the first guest who is no stranger to the Glycanage blood test. Tim has been tracking his biological age for several years, so there is more data to discuss with Dr Nichola, as they delve into how his internal age has changed over time and the various things he was doing to shift the needle.  

With Tim’s new book Ferment: The...

In this bonus episode, our resident scientist Dr. Nicola dives beneath the surface of cosmetic procedures to explore how modern treatments are evolving—from masking aging to actually targeting it at the cellular level.

Discover the science behind biohacking, fillers, skin boosters, and polynucleotides (yes, the “salmon sperm facial”)

We'll hear how these treatments affect your skin’s biology, and hear listener questions answered on l...

Katie Piper spent the second half of her twenties recovering from a violent acid attack, and coming to terms with how her life had permanently changed. Nearly two decades on, her life couldn’t be more different.  

In this wide-ranging conversation, Katie and Katherine cover being a wayward teenagers and how attitudes to alcohol change as you age, the false and short-acting currency of beauty, and how she found faith after ...

In this bonus episode of Dr. Nichola’s Second Opinion, Dr. Nichola Conlon gets into the science behind the hormonal shifts that come with aging, especially during perimenopause and menopause.

She'll explain how hormones like oestrogen and progesterone impact everything from mood and sleep to skin and bone health, and why menopause isn’t just a symptom of aging—it can actually accelerate it.

She'll break down the science behind how H...

He didn’t win the final but Sandro Farmhouse was the star of The Bake Off 2022. 

He takes Katherine behind the scenes and reveals it’s not all sprinkles and icing on the show and tells her the lengths he went to, to get in that infamous tent. 

He’s made cakes for Little Mix, Katherine and hiss show-stopper for Stormzy brought him lots of new followers though not necessarily for the right reason.  

 Sandro’s ea...

In this bonus episode Dr. Nichola Conlon explores the booming world of supplements and biohacking.

Are they truly the secret to slowing aging—or just social media hype? From red light therapy and cold plunges to NAD boosters and collagen powders, Dr. Nic breaks down what’s backed by science and what might be just draining your wallet.

She'll answer your questions about how to pick the right product for you, but if you're thinking ab...

 Having spent her twenties feeling she was both too much and not enough, at 35 Rosie Jones is happy with her age. She talks about growing up with cerebral palsy and how her parents never made her feel any different  - but how it did take her until 4 to get off her arse and start walking! 

She’s making up for it now – a successful writer, stand up and actor – she regularly works 16 hours days.  Her and Katherine d...

In this episode of Dr. Nichola’s Second Opinion, everyone's favourite scientist dives deep into one of the hottest topics in longevity science: gut health.

From understanding what your microbiome is to exploring its powerful influence on aging, inflammation, mental clarity, and even skin health, this episode is packed with science-backed insights and practical advice. 

Dr. Nichola answers listener questions on bloating, brain f...

In Season One, Katherine Ryan’s age came in at 77 years – the oldest on the series. 

She’s bravely taken another test to find out what impact pregnancy had on her biological age and all will be revealed in this episode.  

Katherine lives with the auto-immune condition Lupus and is joined by Dr Chris Wincup, a consultant rheumatologist at King’s College hospital as well as resident scientist Dr Nichola Conlon...

In this eye-opening bonus episode Dr. Nichola explores the impact of drugs and alcohol on your body's age.

From the cellular stress caused by stimulants to the long-term effects of alcohol on our DNA, Dr. Nic breaks down the science behind how our party habits can fast-track our biological age. 

Help is at hand as she offers practical advice on how to support your body’s recovery—even if you’re starting late - and delivers her ...

With two young boys, who fight and bite, a dog and a busy career, Sara Pascoe says at the age of 44 she finally knows what stress feels like.     

She came to motherhood late and conceived via IVF.  She thinks talking openly about the process will remove any shame and tells Katherine, in detail, what happened to her and her body. They discuss how an ageist society even extends to the embryos Sara a...

In this bonus episode, Dr. Nichola explores the science of skin aging—revealing how your skin’s condition reflects your internal health.

From sun damage and pollution to the myths around blue light, Dr. Nick breaks down the biggest culprits behind premature aging and shares her top three “Quick Fixes” to help you protect your skin at the cellular level.

She’s answering your questions on hot topics like SPF, retinol, hydration, and th...

Natalie Cassidy joined the cast of EastEnders when she was still in primary school, at the age of 10, so she would be forgiven for feeling like she’s in her mid 50s when she is only 42.  

Natalie could easily be crowned ‘most down-to-earth person in showbiz’, showing up to the recording fully kitted out in M&S and discussing how much she loves WhatsApping her own loyal listeners about their dirty underwear.  

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As the seasons shift and the nights grow longer, Dr. Nichola Conlon dives into the science of how winter affects our bodies and minds.  

From changes in mood and sleep to skin health and ageing, this episode explores the science behind seasonal shifts and offers practical advice to help you stay well through the colder months. 

And we’ll hear how something as simple as watching a sunset can help us make sure our body c...

Katherine Ryan is 77 but will her partner Bobby Kootstra fare better in the biological age test? 

This episode is a window into the Ryan/Kootstra marriage - they talk about anything and everything - from his upbringing, to his red meat diet to why he doesn’t believe in the moon-landing.  Plus they have a heated debate on what’s best to feed their children.  

Bobby lost his Dad when he was 10 and Katherine’s worrie...

In this episode of Dr. Nicola’s Second Opinion, Dr. Nicola reveals if beauty sleep is just a myth, or is there real science behind waking up looking biologically younger? 

Dr. Nichola dives deep into the structured stages of sleep, from light sleep to deep sleep and RE—revealing how each phase plays a critical role in cellular repair, emotional balance, and even reversing signs of aging.  

She'll answer listener questi...

Jameela Jamil is in the last year of her thirties but she can’t wait to get older. She prefers how she looks now, loves wrinkles and is looking forward to the invisibility that comes to women as they mature.  

The Good Place actress recently returned to the UK from the US because she missed British culture and feels actresses aren’t allowed to age in the States

She’s looking forward to being 85 and with former relativ...

In this energising episode of Dr. Nichola’s Second Opinion, we explore how movement can be a powerful tool in the fight against ageing.

From mitochondria to memory, Dr. Nicola explains how exercise boosts energy, brain health, and cellular function.

 Listener questions cover everything from midlife weight gain and joint stiffness to gym anxiety and forgetfulness.

Plus, comedian Adam Buxton shares his complicated relationship wi...

Emma Barnett is 40 years old and at the top of her game.  She’s regularly up at 330 in the morning to broadcast to the nation and to hold powerful people to account.  But will the early starts and work stress have played havoc with her body?  

Emma’s used to asking the questions but in this frank, thought-provoking conversation, Emma talks openly about the impact of 6 rounds of IVF followed by early years parenti...