MD Longevity Lab: Playing the Long Game
The MD Longevity Lab Podcast is a must-listen for anyone looking to optimize their health and longevity.... without turning it into a full-time job. Hosted by husband-and-wife physicians, Dr. Vikas Patel, MD, and Dr. Nisha Patel, MD, this dynamic series blends cutting-edge medical science with practical, real-world solutions for busy people who want to live longer, healthier lives. With their combined expertise in medicine and lifestyle, Dr. Vikas and Dr. Nisha offer a refreshing, no-nonsense approach to longevity—cutting through the noise and delivering simple, effective strategies that actually fit into your life. Each episode explores the latest research, breakthrough treatments, and easy-to-implement habits that make a real impact on your health. They believe that small, daily deposits into your ’health bank account’ compound over time, leading to massive long-term gains. Whether it’s a quick lifestyle tweak, a science-backed tip, or a groundbreaking medical insight, their goal is to help you make longevity sustainable and achievable. If you’re tired of health advice that feels overwhelming or impossible to sustain, the MD Longevity Lab Podcast is here to change the game. Tune in and discover how small, consistent changes can lead to big results—because at MD Longevity Lab, we are playing the long game. For more information visit them at www.mdlongevitylab.com Disclaimer: This podcast is for informational purposes only and does not constitute medical advice. No doctor-patient relationship is established by listening. Please consult your own physician or healthcare provider before making any medical decisions or starting any new exercise or health program.
Episodes
How to Play the Long Game and Build for 30 Years, Not 30 Days : The Anti-Resolution Manifesto
Hosts: Vikas Patel, MD & Nisha Patel, MD
Episode Summary
80% of New Year's resolutions fail by February. This episode is for the other 20%—and for everyone who's tired of the annual cycle of restriction, guilt, and giving up. This is our anti-resolution manifesto. No 30-day detoxes. No white-knuckling through meals you hate. Inste...
In this episode of MD Longevity Lab: Playing the Long Game, Drs. Nisha and Vikas Patel sit down with world-leading aging researcher Dr. Matt Kaeberlein to cut through the noise in longevity medicine.We discuss why most biological aging clocks fall short, what mTOR actually does, how rapamycin works (and why it’s widely misunderstood), what truly moves the needle for healthspan, and where AI and preventive medicine are headed.This i...
Peptides are everywhere right now — online, in wellness clinics, and all over TikTok. But what’s real? What’s risky? And what actually supports longevity? In this episode, Dr. Nisha and Dr. Vikas break down the hype vs. the science, explain why the Five Pillars of Longevity (Lift, Move, Sleep, Fuel, Connect) always come first, and walk through the peptides patients ask about most.
Key TakeawaysThe Five Pillars come...
In this episode of MD Longevity Lab: Playing the Long Game, Dr. Vikas and Dr. Nisha explore how human connection and gratitude act as powerful, evidence-based tools for both mental health and longevity. They unpack the evolutionary origins of our social brain — from Dunbar’s number to cooperative child-rearing — and explain why humans are biologically wired to thrive in community. The episode highlights the growing loneliness epid...
In this powerful episode, Drs. Nisha and Vikas Patel explore why exercise is the single most effective longevity intervention—and how to train smarter, not harder.
They break down the science, the four essential exercise pillars for long-term health, and a practical weekly blueprint for busy people who want to look, feel, and perform their best for decades to come.
With their signature mix of science, humor, ...
Protein isn’t just for bodybuilders — it’s the longevity macronutrient. In this episode, Drs. Nisha and Vikas Patel break down why protein is essential for muscle, metabolism, and long-term health — and how outdated dietary guidelines have been underselling its importance for decades.
From the science of muscle protein synthesis and turnover to practical strategies for hitting your protein goals (without turning your life into a sp...
In this no-BS crash course, the doctors cover testosterone. Testosterone is one of the most misunderstood and overhyped hormones in medicine today. Often labeled as a “male hormone,” testosterone actually plays a critical role in both men and women—impacting energy, mood, cognition, bone density, muscle mass, and metabolic health. Despite its importance, research shows a concerning trend: average testosterone le...
Perimenopause isn’t just about hot flashes. It’s a full-body transition that impacts your brain, bones, muscles, metabolism, heart, skin, sleep, and more. In this episode, Dr. Nisha Patel and Dr. Vikas Patel break down the science, the physiology, and the real-life experience of navigating perimenopause and menopause.
Expect some real talk (and a few laughs), plus data and strategies you won’t hear in most doctor’s ...
In this episode of the MD Longevity Lab Podcast: Playing the Long Game, Dr. Vikas Patel and Dr. Nisha Patel dive deep into the impact of diabetes and impaired glucose tolerance on long-term healthspan. They unpack the hidden dangers of elevated blood sugar, why so many people are unaware they’re at risk, and how the economic burden of diabetes affects not just individuals but the entire healthcare system.
The conver...
Heart Health & Longevity: Cardiovascular Disease, Lp(a), and Smarter Testing
SummaryCardiovascular disease (CVD) remains the #1 killer in America—claiming one life every 36 seconds and costing the U.S. economy over $365 billion annually. But here’s the hopeful truth: much of it is preventable.
In this episode, Drs. Nisha and Vikas Patel take you on a practical, evidence-based deep dive into heart health. From sobering statisti...
When it comes to aging well, most of us focus on numbers like weight, blood pressure, or
cholesterol. But the real predictors of how well you’ll live into your 60s, 70s, and 80s often havenothing to do with the doctor’s office—and everything to do with how your body moves today. In this episode of MD Longevity Lab: Playing the Long Game, Drs. Vikas and Nisha Patel walk you through nine simple, science-backed tests that you can...
What if one 10-minute scan could give you a crystal-clear snapshot of your future health? In this episode, we break down the Full-Body DEXA Scan—one of the most powerful tools in longevity medicine.
Forget what you thought you knew about DEXA being just for bone density. At MD Longevity Lab, we use advanced DEXA technology to assess body composition, visceral fat, muscle mass, and fat distribution, giving our patients a complet...
What if the secret to living longer wasn’t on a prescription pad—but on a tennis court?
In this episode of MD Longevity Lab, Drs. Nisha and Vikas Patel explore the science-backed reasons why racket sports like tennis, pickleball, and ping pong consistently top the list when it comes to increasing lifespan and improving healthspan.
Unlike traditional cardio, racket sports combine aerobic fitness, explosive power, reflexes, coordinat...
Duration: 45 minutes
Tagline: Snack smarter. Live longer. 🧨 Opening Real Talk Vikas confesses to downing a pint of Graeter’s ice cream and a bag of Flamin’ Hot Cheetos—classic case of knowing better, doing it anyway.
This episode dives into why ultra-processed foods ...
🎙️ Episode 6: Muscle Health 101 — Why Muscle is the True Fountain of Youth
Welcome back to the MD Longevity Lab Podcast — where science meets real life. In today’s episode, we’re digging into one of the most overlooked yet critical drivers of healthspan: skeletal muscle. Drs. Nisha and Vikas Patel break down the science of muscle health and explain why preserving and building muscle is about so much more than aesthetics. Whether y...
In this episode, Drs. Nisha and Vikas Patel break down one of the most foundational—and misunderstood—aspects of health: metabolic health. They explain why metabolic health isn’t just about weight or blood sugar, but a root driver of nearly every major disease process—from heart disease and dementia to cancer and autoimmune conditions.
This episode is your crash course in what metabolic health really means (hint: it’s not just avoi...
In this episode of MD Longevity Lab, we dive into VO2 max—widely regarded as the single best predictor of longevity. It’s a modifiable metric that speaks volumes about your cardiovascular fitness and future healthspan. But before we get into the science, we kick things off with a classic marital squabble (because, of course, nothing says "longevity" like a debate with your spouse about semantics).
Whether you're a weekend warrior,...
Episode 3: What Does It Mean to Play the Long Game?
🎙️ Hosted by Dr. Nisha & Dr. Vikas Patel
We all want to live longer—but what most of us really want is to live better for longer.
In this episode, we break down what it actually means to “play the long game” when it comes to your health. It’s not about perfection or obsessing over every supplement—it’s about building a sustainable, intentional approach to health that suppor...
Episode 2: The Current State of Healthcare – Why the System is Failing Our Healthspan
🎙️ Hosted by Dr. Nisha & Dr. Vikas Patel
In this episode, we dive into the hard truth about the U.S. healthcare system—and why it's not designed to keep you healthy.
Despite spending more on healthcare per person than any other country, only a small percentage of those dollars go toward prevention. Our system is built to treat disease af...
Episode 1: The Origin Story – Why We Started MD Longevity Lab
🎙️ Hosted by Dr. Nisha & Dr. Vikas Patel
In this premiere episode, we’re taking you behind the scenes of MD Longevity Lab—how it started, why we created it, and what you can expect moving forward.
We’re a physician couple raising three kids, juggling busy medical careers, and navigating the real-life challenges of health, aging, and family. But it was our own p...
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