November 27, 2024 • 33 mins
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Speaker 1 (00:00):
There's an old adage that if you want to find
a person's real motives, follow the money. When someone tells
you it's not about the money, rest assured it's about
the money. They say it's not about the money because
they know you know it's about the money, and they
(00:21):
have to address the fact that you're thinking, well, all
you care about is the money. So they say, it's
not about the money, It's about the principle. But is it,
because it never is. I tell you what, then, I
won't pay you the money, but I will do what
(00:42):
you want me to do, and we'll see if this
is about the principle or the money. Well, other money,
A little bit. Money matters a little bit. Joe Biden
and the Democrats decimate our oil industry in favor of
electric vehicles when solar, that's a foolish road to take.
(01:06):
And if you ask yourself if they're stupid or purposely
trying to destroy America, a question that we spent eight
years of the Obama administration trying to figure out. Is
Obama just a complete, blithering idiot or is this all
part of an evil plan? And the reaction seemed to
(01:27):
be split, but the answer for the Biden administration seems
a little simpler than that. You just follow the money.
John Stossel, who is technically a libertarian, but he was
on Fox for many years and now he's off on
his own and he's doing some of the best work
(01:49):
in journalism out there. It's magazine style instead of a
daily report, but he tends to go a little deeper,
and we play some of his stuff here on the
show because us we think it's very well done. He's
got a piece on corporate freeloaders where he explains how
the system works. And I wouldn't call the corporation's freeloaders
(02:12):
as much as i'd call them investors. Instead of investing
in research and development in order to win your heart
your decision making in the marketplace, they invest in politicians.
(02:33):
That's where the money comes from. That drives policy, because
when it comes to solar wind electric you don't make
those decisions in a free marketplace. You make those decisions
because you're compelled. You make those decisions out of guilt.
You make those decisions because the government gives you a
(02:54):
subsidy an incentive to do it. So follow the money.
Speaker 2 (03:00):
In America today, the bigger recipient of handouts is not
poor people, it's corporations.
Speaker 1 (03:07):
Imagination at work.
Speaker 2 (03:09):
GE is the biggest industrial corporation in the world. Here's
their CEO with President Obama.
Speaker 3 (03:16):
Jeff Immelt is perhaps the CEO who's most cozy with
President Obama.
Speaker 2 (03:23):
And Jeff Immolt was recently named the country's jobs are
I am so proud and pleased that Jeff has agreed
to share this package.
Speaker 3 (03:31):
General Electric is structuring their business around where government is going,
so everything from high speed rail, solar wind, General Electric
is lining up to get what government's handing out.
Speaker 2 (03:44):
The New York Times reports that government handed out so
many tax breaks to GE thanks to their fierce lobbying,
that despite billions of dollars in profit, they'll pay no
taxes this year. What's upon a time in America, companies
got money from investors and created wealth by inventing things.
Speaker 4 (04:05):
Twenty five years ago.
Speaker 2 (04:06):
My friends and I started with nothing but an idea.
Microsoft did that. They started with nothing and created billions
in shareholder wealth.
Speaker 3 (04:15):
But then Microsoft is free to compete, and compete aggressively
but not unlawfully.
Speaker 2 (04:22):
The government sued Microsoft for offering people free software at
the time.
Speaker 5 (04:27):
Microsoft spent exactly zero dollars on lobbying. They were busy
changing the world. They were busy creating computer revolution and
helping the Internet revolution. And for that they got drawn
into court. They spent millions and hundreds of millions defending
themselves against the Justice Department. So how much money they
spent today on lobbyists? Hundreds of millions of dollars a year.
Speaker 2 (04:51):
They learned their ugly lessons.
Speaker 5 (04:53):
We created a system in which if you don't do it,
you had a competitive disadvantage.
Speaker 1 (05:00):
A public private partnership, a public private partnership.
Speaker 2 (05:03):
Public private partnership. Businesses love to have a partner in government.
This little window maker must have loved the attention it
got by having the Vice president praise its products.
Speaker 1 (05:14):
You're not just churning out windows, You're making some of
the most energy efficient windows of the world.
Speaker 2 (05:19):
Think getting the vice president was a big deal. Heck,
they got the president too.
Speaker 6 (05:24):
And these workers will now have a new mission producing
some of the most energy efficient windows in the world.
Speaker 2 (05:30):
Other companies don't get so much government help, but this
company gave money to the Democrats, and one of their
executives was married to an important Energy Department official. It
sure is nice to get special government help.
Speaker 6 (05:43):
Thank you, mister Vice President, for your unwavering support.
Speaker 2 (05:47):
Left wing think tanks criticize corporate welfare, but somehow green
handouts they're okay.
Speaker 7 (05:53):
Everybody wants to find a better fuel efficient way to
go about their daily business. The government's to invest in
certain companies to pioneer new technologies that I think is
not corporate welfare.
Speaker 2 (06:06):
The business is too dumb to invest in it without
government saying do this. And here's hell.
Speaker 7 (06:11):
The private sector will only invest if they know for
sure that there is a commercial marketplace.
Speaker 2 (06:17):
But you say everybody wants these things, isn't that enough
incentive for private, greedy businesses to make it.
Speaker 7 (06:23):
The free market does not know anything unless we all
collect our interests and say this is of national import
to us.
Speaker 5 (06:30):
Central planning does not work. It doesn't work in any industry,
It doesn't work in any in any kind of economy.
Speaker 2 (06:37):
But since they're going to centrally plan, they'll give out
special favors to their politically savvy people who are best
at lobbying for them.
Speaker 1 (06:45):
Of at least two hundred million dollars is needed.
Speaker 2 (06:48):
And so the government pours billions of your dollars into
projects like the Roscoe wind farm in Texas. It's half
owned by GE.
Speaker 3 (06:55):
Even if this wind farm produces nothing of value, they
are getting money from the US taxpacker.
Speaker 2 (07:02):
Maybe we don't need win turbine. Maybe it's a waste
of money.
Speaker 7 (07:05):
Well, maybe it is, but it should be one thing
that we as a nation are investing in so that
we aren't left behind some.
Speaker 4 (07:11):
Of the cleanest renewable energy for on Earth.
Speaker 2 (07:15):
GE would not agree to be interviewed. Maybe that's a
good thing if it means companies are now getting embarrassed
about the handouts. Thirteen years ago, when I wanted to
confront a business about it's free loading, the ceo is
so brazen he flew me to his headquarters in one
of his fancy jets, cold gold plated ath else. At
(07:36):
the time, this man was the biggest recipient of handouts.
Duayne Andreas, CEO of ethanol maker ADM. You're a pig
feeding at the welfare trough.
Speaker 6 (07:46):
Why should I care?
Speaker 1 (07:48):
Doesn't bother you out a bit.
Speaker 3 (07:50):
Many beneficiaries of corporate welfare really believe that they're being
paid to help the country. What I'm providing is so
good that it ought to be subsidized.
Speaker 5 (08:02):
Unfortunately, a lot of American companies have become muchas off
the government have been. They go to the guvernment to
manipulate the system in their favor. That's what's not business
is about. That's not what capitalism is about.
Speaker 2 (08:15):
But today, unfortunately, it is a way for capitalists to freedom.
Speaker 1 (08:20):
America is a nation that can be defined in a
single word. I was gonna foot him to put number nine.
Not only was it authentic frontier jibbery, it expressed their.
Speaker 2 (08:30):
Curry scene of this day and the Michael Berry Show
j C.
Speaker 1 (08:35):
You're onld Michael Berry Show, go ahead doing sir.
Speaker 6 (08:39):
Uh Yeah. We take out veterans honning. We partner up
with another group and they bring veterans out that have
been in combat and we get to spend We've been
doing it for about four or five years now. We
get to spend at least the weekend with them and
it's really impactful in their lives and on ours. You
get to hear some stories that are amazing, Touch your
(09:01):
touch your heart, make you realize how blessed we are
here to how easy our lives actually are. Well hear
what they go through. But one of the first guys
I took took out hunting. Uh he Uh, I might
get a choked cats to bear with me.
Speaker 1 (09:19):
Friends, either you get choked up because you care so
passionately about veterans and the experience you gave them. I
got a note you take all the time you want
them turning off on Michael phone.
Speaker 6 (09:32):
So we became real good friends. Funny story is about it.
We were out on had three of them with me.
They wanted to go try to get some coyote's, so
I set up a coyote call, and I knew probably
weren't gonna see anything because we weren't hearing them, and
we've been snaring them pretty good. So we put a
good debt in the population. So I set up a
kyote call, get them all in different areas where we
(09:52):
have different lengths to shoot out of. And I laid
down next to Jonathan and uh, We're sitting there, sitting there,
and he's hunted a lot in his life. And he
looked at him and he goes, they ain't coming, are they? No?
I don't think they are. He goes, man, can we
go look for some sheds? I said, yeah, absolutely, man,
we'll go look for some sheds, talking about antler shed
that fall off every year.
Speaker 1 (10:13):
Hunting. Okay, all right, go ahead, no.
Speaker 6 (10:15):
No sheds. It's actually sheds off, they said, their antlers
every year and you can walk around and pick them up.
Pretty cool deal. And so we're walking around and you know,
just two guys in the woods and I said, man,
so I don't. I said, I'm a very blunt PERSONA Man,
I don't. I don't know how to say it. But
you seem pretty normal, man, So what's what's up with you?
And uh he uh, He's like, man, I've got a
(10:35):
tv I and PTSD. So he was actually uh his
taint got hit by an ID and he was actually
m I A for twenty one days. And uh that
started our relationship right there, and uh, every year since then,
it's been coming up on three years now. We meet
up at least once a year. He actually we just
did a veteran hunt two weekends ago and then he
(10:56):
came in to Pew David Worthing skiving flew in and
we went back to the ranch, did some hunting, and
uh we were sitting, uh, we were sitting upside and
I could tell he was getting Uh. We were talking
and you know, talks to get deep over some some
beers and some whiskey drinks. And uh, one of my
(11:17):
wife's friends was there and she went in decided. And
my wife she's like, I think we're getting sreed. She's like,
leave them alone, let them do the things they got
to get this, you know, get it off their chest.
And she's been around to them, um, so she's just like,
let them be. And Uh, he's taught us about somebody
that he served with that he he helped train, I guess,
and uh, he's wore this bracelet on his wrist, you know,
(11:37):
it says, Uh, I'm gonna read it real quick. I
guess it's some purple David Jay Vines. Sam says in
US Marine Corps Iraqi Freedom eleven six K I A H.
And he's always had this bracelet on him. And when
he goes out on trips or hunts or whatever, he
(11:57):
takes the pictures with that thing. And and said to
that guy's dad, who is now a very good friend
slash father to him and sends pictures to him and
his memory and his honor. And he looked at us,
me and my buddy Jason, that we've all become really
good friends and said, hey, I want to do something
with y'all. He took that bracelet off and put it
(12:19):
down next to us. He said, I'm gonna be back
in the year. I want you to wear it for
six months, and you to wear it for six months
and take pictures and send them to me so I
can send him to his dad. And he hasn't taken
this bracelet off in years. And to be entrusted with
something like that is it is really amazing. And you know,
(12:40):
it all started over relationships, over over a deer hunt.
And I've dealt with several of these guys now and
we look at it as age, just a deer man.
It's you know, if you have a scale where you
put one thing on one side and one on the other,
it goes up and down. We look at what they
did and that scale was weighted down heavy on their side,
and we look at it going. Man, we just all
were to being able to do this, give you a
hunt and gives you a deer and just listen to
(13:02):
y'all and talk with y'all, and it's just no comparison.
The one thing I've learned is it's the exact opposite
to them. It's not just a deer to them. Hearing
some of these stories, one of the guys told us
that one of his friends, you know, was blown up
missing an armor leg type deal, and always turned out
in these hunts and finally went on one because he
(13:22):
was debating suicide and shot a deer and was able
to put food on the table. And he told us
that literally this saved that man's life one of these
hunts that he realized he's still a man. He can
still put food on his table to support his family
and man if y'all have opportunities that you own a
ranch or you're part of something, whether it's hunting, fishing.
I know they do fishing trips, to do all kinds
(13:42):
of stuff. Reach out to these different organizations. The one
that we deal with is Combat Ring out Doors, which
was started by two Marines, but they do every branch
of the military and they bring these guys out. Man,
it's truly life changing for them and you get to
see them decompressed. And the two weekends ago, the one
night I took he had TBI and PTSD. He was
hit by three IED's and he just looked at me
(14:05):
while we're in the stand and he said, man, thank
you so much. I was able to unplug for three
days and I really felt peace for the first time
in a while. So it's just it's it's an amazing
experience for everybody.
Speaker 4 (14:19):
J C.
Speaker 1 (14:19):
First of all, thank you for doing that. And I
suspect you would agree with my assessment that you took
more away from that time you spent with that better
and than he did. And that's not to diminish what
it meant to him. It's that very few things in
life will give you the fulfillment that that did.
Speaker 6 (14:41):
Yeah, And it's and I've been blessed with a good family,
wife and kids that you know, they let me take
time away from our schedule to go do this for them,
and it's it's it's even though my family's not always there,
my family's there and we're all saying thank you to them,
and Jenny any better than who the service, thank you.
Speaker 2 (15:01):
You know.
Speaker 1 (15:08):
Yes, one of the things I'll tell you that I've
been doing radio for seventeen years and I've had other
careers and I've done things for people in some way
or another. And I often say this and it makes
people uncomfortable, but it is true. People don't want to
admit this, but that which we do for other people,
(15:33):
we do because we are selfish, extremely selfish. Now people
will say, I am so self less. I do things
for other people to help other people. If doing things
to help other people did not give us a sense
(15:54):
of fulfillment on a profound level, we wouldn't do it.
We wouldn't. And I will tell you that we landed
on combat veterans with PTSD and that has occupied a
great deal of my energy since then. It's been ten
years now, which you celebrated ten years Camp Hope. And
(16:16):
the beauty is especially for guys if you if you
are a hunting and fishing guy, you got to realize
the people who went and served in Afghanistan and Iraq.
You think about the demographic. A large number of those
guys are rednecks from small towns that love to hunt
and fish. And when you think about you've got something
(16:38):
that you don't even think of you it's deer huntings. Easy,
you go deer hunt, or you go out fishing, or
you know, you do outdoors activities. Man, that's you could
take that guy to the ball game, sure that's fine,
but you take him fishing. Oh, man, and I will,
I will promise you this. I will, I will make
(16:59):
this guarantee to you if you do that for a
combat veterans suffering from PTSD. You get out there, you'll
feel so good about yourself as you're going, I'm gonna
take some veterans out because you want the credit, right,
I'm gonna text some veterans out. I'm gonna do this
we have and you'll get out there and the new
will wear off of that penny. The shine will wear off,
(17:20):
and a few hours into it, you will realize you
are going to gain more from this experience than that
guy is, because this is going to put it all
into perspective. Because you sleep like a baby through the night,
because you have full use of all your appendages, you
will find because you don't have horrible nightmares and desires
(17:41):
to kill yourself, and you don't have tattoos that remind
you of their buddy who they had to carry to
the helicopter to be hauled away so that he could
be brought home at least as a body to be buried.
Those are things you never forget. You will from that
experience be forever change.
Speaker 2 (17:58):
You've got the Schoolberry's show.
Speaker 1 (18:01):
All right, I'm going to call this segment, or ask
you to slug this segment as sleep, all things related
to sleep. And here it goes, ask yourself, are you
getting a minimum solid seven hours of sleep per night?
(18:24):
Because if you're not, it will affect every other aspect
of your life, every other aspect. For most of my
life I have gone, on frequent occasion on three or
four hours of sleep, and before I was fifty, I
could get away with that. And one of my great
(18:44):
life skills that everybody who knew me well would always
remark was that I could stay up later than you
can imagine, drink more than you can imagine, smoke more
cigars than you can imagine, eat more fried chicken or
barbecue than you could imagine, and get up two hours
(19:05):
later and do the show without a single person knowing.
And so people will be at my house till four thirty,
Go catch a little cat nap hour, wake up, get
into the studio, do the show. And about eleven thirty,
after we'd gone off air and we're working on production
elements and writing bits and all that, people would email
(19:28):
me from the night before and Ninka, hey did you
do the show? Because I just woke up. Yeah, I
did to tell that's what I do, but that will
wreck your body, wreck it. And I know you're not
doing that, but let me just let me just out
of love for you, our listeners give you a little
bit of advice that you didn't ask for, but I
(19:50):
hope you'll take it in the right vein. If you'll
get more sleep, it will solve a lot of your problems,
including but not limited to weight. So I try to
get eight hours sleep right now. I'm in the middle
of a really good book. So last night I read
in bed, which I like to do because you fall
(20:11):
asleep real nice. But finally my wife was like, all right,
let's go to sleep, and so I did. But I
didn't get my full I didn't get my full night
of sleep like I like to do. But that's a
rare event. Even that was just a little bit short.
You will find it much easier to fast or do
(20:33):
whatever you're dieting on if you have more sleep. If
you are short of sleep, you will find that comfort
food is your friend. It's very, very hard to cut
back your caloric intake on short sleep. You're cranky and
your resistance is down. If you're not getting a full
night of sleep every single night, you're not going to
(20:53):
lose weight. That's a fact. Doctors will tell you that
focus on this sort of stuff. Fat people famously don't
get sleep. They don't they stay up all night, they
turn the TV on, they flip channels all night, they
stay up all night. And whether you eat in bed
late at night, which is also another horrible habit. But
if you do that, you're also extending the night and
(21:16):
not getting enough sleep. You can't possibly do what you
need to do the next day. And this is coming
from a person who has struggled my entire life to
go to sleep because I don't want the data end.
But now I call my parents every night by eight
o'clock and my Mama, you sound like you're going to
bed at when we hang up, I'm going I'm gonna
(21:37):
spend a little time with the kids, catch up on
the day, and I'm going to bed with the goal
of being asleep as early as possible, which I never done.
I have never ever done. My dad always wanted me to.
You got to get more sleep, and that means a
couple of things. That means you've got to shut down
all the digital things you can read about it. I'm
not gonna waste a bunch of your time. But if
(21:58):
you're on that damn phone, nothing you're doing is useful.
You're just killing time. It becomes I hate to overuse
the word addiction, but it becomes sort of an addiction,
becomes a habit. You get habituated to it, and it's
emanating from that blue screen a message to your brain
that says, don't shut down, you don't send the serotonins,
(22:19):
you don't start to slow down, put that thing away,
and don't leave it next Unless you are an overnight
tow truck driver or a fireman, a volunteer fireman, you
do not need to be reached in the middle of
the night. Ninety five percent of people who have their
phone next to their bed. That's the worst thing you
can do, because then you get some idiot like me
(22:40):
that's drunk at two o'clock in the morning calling you
and you're picking up because there's a group going high way.
I'm done, well, I'm sleeping, Michael is two o'clock. We're
all here and we're talking about y who we're what
are you? Ain'ty there?
Speaker 6 (22:55):
Yeah?
Speaker 1 (22:55):
Yes, she's asleep, Okay, Okay, we're here, we're you were
what you're talking about. You don't need that call. That
call will appear as a lost call. The other thing
is people call you at two o'clock in the morning
to bail them out from a DWI or get them
out of trouble. Or you don't need to be that either.
You don't need to help them out of their bad decisions.
Let them dry out in the tank, and late the
(23:18):
next morning they'll they get another call. They give them
a few calls so they get an Oh, they might
call somebody it's closer to them than you are, and
then you didn't have to go pick them up in
the first place and waste all that time. Uh, turn,
put your phone in another room and turn off the ringer.
You don't need the ringer. Geez, turn the damn ringer
off all the time. Put it in another room where
(23:39):
it can't bother you. If at all possible, do these things.
Make your room as dark as possible. No lights, none,
no lights in your room, period, end of story. Make
it cold. Every study you'll read will tell you the
human body is meant to sleep better when it's cold.
There's a number of reason put a blanket, under weighted blankets.
(24:02):
There's all sorts of studies that say waited blankets worth.
I don't like a weighted blanket, but my wife does,
and a lot of other people do. Get to bed
on time with the intention of going to sleep, free
your mind, maybe read a little bit, but set a
time that you're going to go to sleep, and lay there,
and even if you just lay there and can't fall asleep,
(24:22):
make it completely quiet or do your white noise. Some
people do that, and sit there and let your body
de escalate from the stress of the day. You don't
need to worry about Joe Biden and Nancy Pelosi at
exactly that moment. You need to replenish. Drink water, Drink
more water, and when you're done, drink more water. After that,
(24:46):
get every ounce of sleep you can possibly get if
you don't have a comfortable mattress. Go see Mac. Mac
lives off the fact that people want to get better sleep,
and for good reason, because good sleep is critical your
good health. That's all I got on sleeping the moment, Oh, magnesium.
Magnesium allows me to sleep better than anything else.
Speaker 3 (25:15):
Side.
Speaker 1 (25:23):
If you compliment your friend or your friend's wife as
to them looking great. They've lost weight. What are you doing?
Are you working out? Are you intermittent fasting? You look fantastic.
Somebody who's been carrying an extra twenty or sixty pounds
(25:44):
for a very long time, all of a sudden has
a little spring in their step. And it's not just women.
Men carry themselves differently. When they've dropped down three, four
five sizes in their jeans, they start tucking their shirt in.
Oh my goodness, instead of tennis shoes with their genes,
they're wearing loafers, they're wearing dress shoes. They're all of
(26:06):
a sudden getting their hairstyled. It's a change in your
entire presentation. You can see the swagger in people. They've
been married for twenty five years and now all of
a sudden, they're acting like they used to when they
wooed their lover. Well, ozimpic is often the answer. And
I can't pronounce the word. I'll get the pronunciation. It's semiglitudes.
(26:28):
I'm not sure how you pronounce it. But our expert.
We went searching for an expert, and some of you
will know we have talked about this subject before. We
have had other doctors on to talk about this, but
it is such a common phenomenon, cultural trend and a
medical issue, and you know, I'm fascinated by those that
we are having an expert on the matter with us today.
(26:51):
Her name is doctor Archin Nosadu. She is a Board
certified endocrinologist specializing in diabetes and she is the director
of the System Diabetes Program at Houston Methodist. She is
specifically with us to talk about that diabetes drug. It's
actually being used as a diet drug causing some problems
(27:13):
for diabetics who really need the drug. Doctor Sadou, First
of all, why are we hearing ozimpic all the time?
What is so special about this drug?
Speaker 4 (27:25):
Well, thank you for having me here today, Michael. And yes,
it's all over the headlines and it seems to be
something new each time, but it actually it's been in
our toolbox for many years for type two diabetes, which
is what it was originally studied and approved for, because
it really lowered patient's blood sugars dramatically. But in those
(27:47):
studies it was also noted that they had a significant
weight loss. So then subsequently that drug semaglutide was studied
for just weight loss, so people without the diagnosis of
diabetes and again proved itself to be a great drug
to help people lose weight, and then it got FDA
(28:09):
approval for that indication. The drug is the same which
is semaglue hide, but for diabetes it's the brand name
is ozempic, and then for weightless alone it's called Wagovy.
So I think we're everyone's just kind of used to
the first name ozempic, but that's why we hear the
(28:29):
term ozempic all the time. But it could be either
ozempic or with goovy, which is the same drug.
Speaker 1 (28:36):
I want to talk about the differences between that and
why it's marketed separately because that's important for pharmaceutical REGs.
But first explain to me, like I'm in about seventh grade,
what exactly does ozempic or WEGOV do.
Speaker 4 (28:53):
So. Ozempic or the drug semaglue hide is a replica
of a hormone and we have naturally in our gut system,
which is called GLP one, And this hormone is secreted
as soon as we eat something, and it has several duties. Naturally,
(29:14):
one it delays the emptying of the stomach, so food
comes in lower, slower and gets absorbed more efficiently with
balancing the glucose that's being absorbed so that our blood
sugars don't get too high. And two, it also raises
the pincreas's ability to secrete insulin, again balancing blood sugars,
(29:39):
which is where its first effect was most exciting. But
third effect, which was unexpected, was that it actually also
works on the appetite center in the brain to decrease appetite.
And this all makes sense, right, So whenever we eat,
we want to feel full, we want to balance the
nutrients we're absorbing, and then we want to stop eating,
(30:01):
so we just don't keep eating all the time. So
this drug is there for those purposes. And what we've
done is in this synthetic version semagluetide, and there's others
just like it as well. This is just one brand
we've We've given it in a subcutaneous injection form at
(30:22):
much much higher levels than what our gut normally secretes
to enhance these effects of decreased appetite and what you're lowering.
So that's that's how the drugs are working.
Speaker 1 (30:35):
Let's take those one by one. But before we do that,
you said Ozimpic and Wigov are just one brand? Are
there other products out there? It sounds like you're loyal
to or partial to ozimpic. There's Manjara or something like that.
Are those all, as I understand it, they're all semi
(30:56):
glue tide semiglue tides. Are they all about the same?
Is there a reason you prefer ozimpic.
Speaker 4 (31:03):
Well, it's not about preference. So a little bit about
the history. The first drug of the class was actually
a totally different drug called exenotide, but the brand name Baieta,
and that was the very first version of this whole class. Subsequently,
we got loraglatide or also called victosa or sexenda, and
(31:28):
then the most recent one a semiglutide or ozempic, and
regovi really got attention because these were weakly injectable, so
much easier to use, much more tolerable for patients, and
so they gained in popularity. Munjaro is a brand new player,
which is terzepetide. It's another compound entirely, and it is
(31:54):
one step above ozembic even because it combines two hormones
that are secreted in our gut, whereas previously it was
just the gop one that I mentioned to eppetiteer. Manjaro
also adds GIP and not to confuse you or the audience,
but we're actually building even more on these gut hormones
(32:16):
in upcoming drugs. So they're all very they're all different,
although do the same thing in our digestive tracks and
the brain to have the end outcome be eating less,
balancing your blood sugar and weight box.
Speaker 1 (32:33):
All right, I'm going to hold you right there for
just a moment. We're talking to doctor Archinas Sadu spelled
sad Hu is the board certified into chronologists and hormones
and she specializes in debut He is the director of
the System Diabetes Program at Houston Methodist and we'll continue
(32:54):
our conversation with her coming up
There's an old adage that if you want to find
a person's real motives, follow the money. When someone tells
you it's not about the money, rest assured it's about
the money. They say it's not about the money because
they know you know it's about the money, and they
(00:21):
have to address the fact that you're thinking, well, all
you care about is the money. So they say, it's
not about the money, It's about the principle. But is it,
because it never is. I tell you what, then, I
won't pay you the money, but I will do what
(00:42):
you want me to do, and we'll see if this
is about the principle or the money. Well, other money,
A little bit. Money matters a little bit. Joe Biden
and the Democrats decimate our oil industry in favor of
electric vehicles when solar, that's a foolish road to take.
(01:06):
And if you ask yourself if they're stupid or purposely
trying to destroy America, a question that we spent eight
years of the Obama administration trying to figure out. Is
Obama just a complete, blithering idiot or is this all
part of an evil plan? And the reaction seemed to
(01:27):
be split, but the answer for the Biden administration seems
a little simpler than that. You just follow the money.
John Stossel, who is technically a libertarian, but he was
on Fox for many years and now he's off on
his own and he's doing some of the best work
(01:49):
in journalism out there. It's magazine style instead of a
daily report, but he tends to go a little deeper,
and we play some of his stuff here on the
show because us we think it's very well done. He's
got a piece on corporate freeloaders where he explains how
the system works. And I wouldn't call the corporation's freeloaders
(02:12):
as much as i'd call them investors. Instead of investing
in research and development in order to win your heart
your decision making in the marketplace, they invest in politicians.
(02:33):
That's where the money comes from. That drives policy, because
when it comes to solar wind electric you don't make
those decisions in a free marketplace. You make those decisions
because you're compelled. You make those decisions out of guilt.
You make those decisions because the government gives you a
(02:54):
subsidy an incentive to do it. So follow the money.
Speaker 2 (03:00):
In America today, the bigger recipient of handouts is not
poor people, it's corporations.
Speaker 1 (03:07):
Imagination at work.
Speaker 2 (03:09):
GE is the biggest industrial corporation in the world. Here's
their CEO with President Obama.
Speaker 3 (03:16):
Jeff Immelt is perhaps the CEO who's most cozy with
President Obama.
Speaker 2 (03:23):
And Jeff Immolt was recently named the country's jobs are
I am so proud and pleased that Jeff has agreed
to share this package.
Speaker 3 (03:31):
General Electric is structuring their business around where government is going,
so everything from high speed rail, solar wind, General Electric
is lining up to get what government's handing out.
Speaker 2 (03:44):
The New York Times reports that government handed out so
many tax breaks to GE thanks to their fierce lobbying,
that despite billions of dollars in profit, they'll pay no
taxes this year. What's upon a time in America, companies
got money from investors and created wealth by inventing things.
Speaker 4 (04:05):
Twenty five years ago.
Speaker 2 (04:06):
My friends and I started with nothing but an idea.
Microsoft did that. They started with nothing and created billions
in shareholder wealth.
Speaker 3 (04:15):
But then Microsoft is free to compete, and compete aggressively
but not unlawfully.
Speaker 2 (04:22):
The government sued Microsoft for offering people free software at
the time.
Speaker 5 (04:27):
Microsoft spent exactly zero dollars on lobbying. They were busy
changing the world. They were busy creating computer revolution and
helping the Internet revolution. And for that they got drawn
into court. They spent millions and hundreds of millions defending
themselves against the Justice Department. So how much money they
spent today on lobbyists? Hundreds of millions of dollars a year.
Speaker 2 (04:51):
They learned their ugly lessons.
Speaker 5 (04:53):
We created a system in which if you don't do it,
you had a competitive disadvantage.
Speaker 1 (05:00):
A public private partnership, a public private partnership.
Speaker 2 (05:03):
Public private partnership. Businesses love to have a partner in government.
This little window maker must have loved the attention it
got by having the Vice president praise its products.
Speaker 1 (05:14):
You're not just churning out windows, You're making some of
the most energy efficient windows of the world.
Speaker 2 (05:19):
Think getting the vice president was a big deal. Heck,
they got the president too.
Speaker 6 (05:24):
And these workers will now have a new mission producing
some of the most energy efficient windows in the world.
Speaker 2 (05:30):
Other companies don't get so much government help, but this
company gave money to the Democrats, and one of their
executives was married to an important Energy Department official. It
sure is nice to get special government help.
Speaker 6 (05:43):
Thank you, mister Vice President, for your unwavering support.
Speaker 2 (05:47):
Left wing think tanks criticize corporate welfare, but somehow green
handouts they're okay.
Speaker 7 (05:53):
Everybody wants to find a better fuel efficient way to
go about their daily business. The government's to invest in
certain companies to pioneer new technologies that I think is
not corporate welfare.
Speaker 2 (06:06):
The business is too dumb to invest in it without
government saying do this. And here's hell.
Speaker 7 (06:11):
The private sector will only invest if they know for
sure that there is a commercial marketplace.
Speaker 2 (06:17):
But you say everybody wants these things, isn't that enough
incentive for private, greedy businesses to make it.
Speaker 7 (06:23):
The free market does not know anything unless we all
collect our interests and say this is of national import
to us.
Speaker 5 (06:30):
Central planning does not work. It doesn't work in any industry,
It doesn't work in any in any kind of economy.
Speaker 2 (06:37):
But since they're going to centrally plan, they'll give out
special favors to their politically savvy people who are best
at lobbying for them.
Speaker 1 (06:45):
Of at least two hundred million dollars is needed.
Speaker 2 (06:48):
And so the government pours billions of your dollars into
projects like the Roscoe wind farm in Texas. It's half
owned by GE.
Speaker 3 (06:55):
Even if this wind farm produces nothing of value, they
are getting money from the US taxpacker.
Speaker 2 (07:02):
Maybe we don't need win turbine. Maybe it's a waste
of money.
Speaker 7 (07:05):
Well, maybe it is, but it should be one thing
that we as a nation are investing in so that
we aren't left behind some.
Speaker 4 (07:11):
Of the cleanest renewable energy for on Earth.
Speaker 2 (07:15):
GE would not agree to be interviewed. Maybe that's a
good thing if it means companies are now getting embarrassed
about the handouts. Thirteen years ago, when I wanted to
confront a business about it's free loading, the ceo is
so brazen he flew me to his headquarters in one
of his fancy jets, cold gold plated ath else. At
(07:36):
the time, this man was the biggest recipient of handouts.
Duayne Andreas, CEO of ethanol maker ADM. You're a pig
feeding at the welfare trough.
Speaker 6 (07:46):
Why should I care?
Speaker 1 (07:48):
Doesn't bother you out a bit.
Speaker 3 (07:50):
Many beneficiaries of corporate welfare really believe that they're being
paid to help the country. What I'm providing is so
good that it ought to be subsidized.
Speaker 5 (08:02):
Unfortunately, a lot of American companies have become muchas off
the government have been. They go to the guvernment to
manipulate the system in their favor. That's what's not business
is about. That's not what capitalism is about.
Speaker 2 (08:15):
But today, unfortunately, it is a way for capitalists to freedom.
Speaker 1 (08:20):
America is a nation that can be defined in a
single word. I was gonna foot him to put number nine.
Not only was it authentic frontier jibbery, it expressed their.
Speaker 2 (08:30):
Curry scene of this day and the Michael Berry Show
j C.
Speaker 1 (08:35):
You're onld Michael Berry Show, go ahead doing sir.
Speaker 6 (08:39):
Uh Yeah. We take out veterans honning. We partner up
with another group and they bring veterans out that have
been in combat and we get to spend We've been
doing it for about four or five years now. We
get to spend at least the weekend with them and
it's really impactful in their lives and on ours. You
get to hear some stories that are amazing, Touch your
(09:01):
touch your heart, make you realize how blessed we are
here to how easy our lives actually are. Well hear
what they go through. But one of the first guys
I took took out hunting. Uh he Uh, I might
get a choked cats to bear with me.
Speaker 1 (09:19):
Friends, either you get choked up because you care so
passionately about veterans and the experience you gave them. I
got a note you take all the time you want
them turning off on Michael phone.
Speaker 6 (09:32):
So we became real good friends. Funny story is about it.
We were out on had three of them with me.
They wanted to go try to get some coyote's, so
I set up a coyote call, and I knew probably
weren't gonna see anything because we weren't hearing them, and
we've been snaring them pretty good. So we put a
good debt in the population. So I set up a
kyote call, get them all in different areas where we
(09:52):
have different lengths to shoot out of. And I laid
down next to Jonathan and uh, We're sitting there, sitting there,
and he's hunted a lot in his life. And he
looked at him and he goes, they ain't coming, are they? No?
I don't think they are. He goes, man, can we
go look for some sheds? I said, yeah, absolutely, man,
we'll go look for some sheds, talking about antler shed
that fall off every year.
Speaker 1 (10:13):
Hunting. Okay, all right, go ahead, no.
Speaker 6 (10:15):
No sheds. It's actually sheds off, they said, their antlers
every year and you can walk around and pick them up.
Pretty cool deal. And so we're walking around and you know,
just two guys in the woods and I said, man,
so I don't. I said, I'm a very blunt PERSONA Man,
I don't. I don't know how to say it. But
you seem pretty normal, man, So what's what's up with you?
And uh he uh, He's like, man, I've got a
(10:35):
tv I and PTSD. So he was actually uh his
taint got hit by an ID and he was actually
m I A for twenty one days. And uh that
started our relationship right there, and uh, every year since then,
it's been coming up on three years now. We meet
up at least once a year. He actually we just
did a veteran hunt two weekends ago and then he
(10:56):
came in to Pew David Worthing skiving flew in and
we went back to the ranch, did some hunting, and
uh we were sitting, uh, we were sitting upside and
I could tell he was getting Uh. We were talking
and you know, talks to get deep over some some
beers and some whiskey drinks. And uh, one of my
(11:17):
wife's friends was there and she went in decided. And
my wife she's like, I think we're getting sreed. She's like,
leave them alone, let them do the things they got
to get this, you know, get it off their chest.
And she's been around to them, um, so she's just like,
let them be. And Uh, he's taught us about somebody
that he served with that he he helped train, I guess,
and uh, he's wore this bracelet on his wrist, you know,
(11:37):
it says, Uh, I'm gonna read it real quick. I
guess it's some purple David Jay Vines. Sam says in
US Marine Corps Iraqi Freedom eleven six K I A H.
And he's always had this bracelet on him. And when
he goes out on trips or hunts or whatever, he
(11:57):
takes the pictures with that thing. And and said to
that guy's dad, who is now a very good friend
slash father to him and sends pictures to him and
his memory and his honor. And he looked at us,
me and my buddy Jason, that we've all become really
good friends and said, hey, I want to do something
with y'all. He took that bracelet off and put it
(12:19):
down next to us. He said, I'm gonna be back
in the year. I want you to wear it for
six months, and you to wear it for six months
and take pictures and send them to me so I
can send him to his dad. And he hasn't taken
this bracelet off in years. And to be entrusted with
something like that is it is really amazing. And you know,
(12:40):
it all started over relationships, over over a deer hunt.
And I've dealt with several of these guys now and
we look at it as age, just a deer man.
It's you know, if you have a scale where you
put one thing on one side and one on the other,
it goes up and down. We look at what they
did and that scale was weighted down heavy on their side,
and we look at it going. Man, we just all
were to being able to do this, give you a
hunt and gives you a deer and just listen to
(13:02):
y'all and talk with y'all, and it's just no comparison.
The one thing I've learned is it's the exact opposite
to them. It's not just a deer to them. Hearing
some of these stories, one of the guys told us
that one of his friends, you know, was blown up
missing an armor leg type deal, and always turned out
in these hunts and finally went on one because he
(13:22):
was debating suicide and shot a deer and was able
to put food on the table. And he told us
that literally this saved that man's life one of these
hunts that he realized he's still a man. He can
still put food on his table to support his family
and man if y'all have opportunities that you own a
ranch or you're part of something, whether it's hunting, fishing.
I know they do fishing trips, to do all kinds
(13:42):
of stuff. Reach out to these different organizations. The one
that we deal with is Combat Ring out Doors, which
was started by two Marines, but they do every branch
of the military and they bring these guys out. Man,
it's truly life changing for them and you get to
see them decompressed. And the two weekends ago, the one
night I took he had TBI and PTSD. He was
hit by three IED's and he just looked at me
(14:05):
while we're in the stand and he said, man, thank
you so much. I was able to unplug for three
days and I really felt peace for the first time
in a while. So it's just it's it's an amazing
experience for everybody.
Speaker 4 (14:19):
J C.
Speaker 1 (14:19):
First of all, thank you for doing that. And I
suspect you would agree with my assessment that you took
more away from that time you spent with that better
and than he did. And that's not to diminish what
it meant to him. It's that very few things in
life will give you the fulfillment that that did.
Speaker 6 (14:41):
Yeah, And it's and I've been blessed with a good family,
wife and kids that you know, they let me take
time away from our schedule to go do this for them,
and it's it's it's even though my family's not always there,
my family's there and we're all saying thank you to them,
and Jenny any better than who the service, thank you.
Speaker 2 (15:01):
You know.
Speaker 1 (15:08):
Yes, one of the things I'll tell you that I've
been doing radio for seventeen years and I've had other
careers and I've done things for people in some way
or another. And I often say this and it makes
people uncomfortable, but it is true. People don't want to
admit this, but that which we do for other people,
(15:33):
we do because we are selfish, extremely selfish. Now people
will say, I am so self less. I do things
for other people to help other people. If doing things
to help other people did not give us a sense
(15:54):
of fulfillment on a profound level, we wouldn't do it.
We wouldn't. And I will tell you that we landed
on combat veterans with PTSD and that has occupied a
great deal of my energy since then. It's been ten
years now, which you celebrated ten years Camp Hope. And
(16:16):
the beauty is especially for guys if you if you
are a hunting and fishing guy, you got to realize
the people who went and served in Afghanistan and Iraq.
You think about the demographic. A large number of those
guys are rednecks from small towns that love to hunt
and fish. And when you think about you've got something
(16:38):
that you don't even think of you it's deer huntings. Easy,
you go deer hunt, or you go out fishing, or
you know, you do outdoors activities. Man, that's you could
take that guy to the ball game, sure that's fine,
but you take him fishing. Oh, man, and I will,
I will promise you this. I will, I will make
(16:59):
this guarantee to you if you do that for a
combat veterans suffering from PTSD. You get out there, you'll
feel so good about yourself as you're going, I'm gonna
take some veterans out because you want the credit, right,
I'm gonna text some veterans out. I'm gonna do this
we have and you'll get out there and the new
will wear off of that penny. The shine will wear off,
(17:20):
and a few hours into it, you will realize you
are going to gain more from this experience than that
guy is, because this is going to put it all
into perspective. Because you sleep like a baby through the night,
because you have full use of all your appendages, you
will find because you don't have horrible nightmares and desires
(17:41):
to kill yourself, and you don't have tattoos that remind
you of their buddy who they had to carry to
the helicopter to be hauled away so that he could
be brought home at least as a body to be buried.
Those are things you never forget. You will from that
experience be forever change.
Speaker 2 (17:58):
You've got the Schoolberry's show.
Speaker 1 (18:01):
All right, I'm going to call this segment, or ask
you to slug this segment as sleep, all things related
to sleep. And here it goes, ask yourself, are you
getting a minimum solid seven hours of sleep per night?
(18:24):
Because if you're not, it will affect every other aspect
of your life, every other aspect. For most of my
life I have gone, on frequent occasion on three or
four hours of sleep, and before I was fifty, I
could get away with that. And one of my great
(18:44):
life skills that everybody who knew me well would always
remark was that I could stay up later than you
can imagine, drink more than you can imagine, smoke more
cigars than you can imagine, eat more fried chicken or
barbecue than you could imagine, and get up two hours
(19:05):
later and do the show without a single person knowing.
And so people will be at my house till four thirty,
Go catch a little cat nap hour, wake up, get
into the studio, do the show. And about eleven thirty,
after we'd gone off air and we're working on production
elements and writing bits and all that, people would email
(19:28):
me from the night before and Ninka, hey did you
do the show? Because I just woke up. Yeah, I
did to tell that's what I do, but that will
wreck your body, wreck it. And I know you're not
doing that, but let me just let me just out
of love for you, our listeners give you a little
bit of advice that you didn't ask for, but I
(19:50):
hope you'll take it in the right vein. If you'll
get more sleep, it will solve a lot of your problems,
including but not limited to weight. So I try to
get eight hours sleep right now. I'm in the middle
of a really good book. So last night I read
in bed, which I like to do because you fall
(20:11):
asleep real nice. But finally my wife was like, all right,
let's go to sleep, and so I did. But I
didn't get my full I didn't get my full night
of sleep like I like to do. But that's a
rare event. Even that was just a little bit short.
You will find it much easier to fast or do
(20:33):
whatever you're dieting on if you have more sleep. If
you are short of sleep, you will find that comfort
food is your friend. It's very, very hard to cut
back your caloric intake on short sleep. You're cranky and
your resistance is down. If you're not getting a full
night of sleep every single night, you're not going to
(20:53):
lose weight. That's a fact. Doctors will tell you that
focus on this sort of stuff. Fat people famously don't
get sleep. They don't they stay up all night, they
turn the TV on, they flip channels all night, they
stay up all night. And whether you eat in bed
late at night, which is also another horrible habit. But
if you do that, you're also extending the night and
(21:16):
not getting enough sleep. You can't possibly do what you
need to do the next day. And this is coming
from a person who has struggled my entire life to
go to sleep because I don't want the data end.
But now I call my parents every night by eight
o'clock and my Mama, you sound like you're going to
bed at when we hang up, I'm going I'm gonna
(21:37):
spend a little time with the kids, catch up on
the day, and I'm going to bed with the goal
of being asleep as early as possible, which I never done.
I have never ever done. My dad always wanted me to.
You got to get more sleep, and that means a
couple of things. That means you've got to shut down
all the digital things you can read about it. I'm
not gonna waste a bunch of your time. But if
(21:58):
you're on that damn phone, nothing you're doing is useful.
You're just killing time. It becomes I hate to overuse
the word addiction, but it becomes sort of an addiction,
becomes a habit. You get habituated to it, and it's
emanating from that blue screen a message to your brain
that says, don't shut down, you don't send the serotonins,
(22:19):
you don't start to slow down, put that thing away,
and don't leave it next Unless you are an overnight
tow truck driver or a fireman, a volunteer fireman, you
do not need to be reached in the middle of
the night. Ninety five percent of people who have their
phone next to their bed. That's the worst thing you
can do, because then you get some idiot like me
(22:40):
that's drunk at two o'clock in the morning calling you
and you're picking up because there's a group going high way.
I'm done, well, I'm sleeping, Michael is two o'clock. We're
all here and we're talking about y who we're what
are you? Ain'ty there?
Speaker 6 (22:55):
Yeah?
Speaker 1 (22:55):
Yes, she's asleep, Okay, Okay, we're here, we're you were
what you're talking about. You don't need that call. That
call will appear as a lost call. The other thing
is people call you at two o'clock in the morning
to bail them out from a DWI or get them
out of trouble. Or you don't need to be that either.
You don't need to help them out of their bad decisions.
Let them dry out in the tank, and late the
(23:18):
next morning they'll they get another call. They give them
a few calls so they get an Oh, they might
call somebody it's closer to them than you are, and
then you didn't have to go pick them up in
the first place and waste all that time. Uh, turn,
put your phone in another room and turn off the ringer.
You don't need the ringer. Geez, turn the damn ringer
off all the time. Put it in another room where
(23:39):
it can't bother you. If at all possible, do these things.
Make your room as dark as possible. No lights, none,
no lights in your room, period, end of story. Make
it cold. Every study you'll read will tell you the
human body is meant to sleep better when it's cold.
There's a number of reason put a blanket, under weighted blankets.
(24:02):
There's all sorts of studies that say waited blankets worth.
I don't like a weighted blanket, but my wife does,
and a lot of other people do. Get to bed
on time with the intention of going to sleep, free
your mind, maybe read a little bit, but set a
time that you're going to go to sleep, and lay there,
and even if you just lay there and can't fall asleep,
(24:22):
make it completely quiet or do your white noise. Some
people do that, and sit there and let your body
de escalate from the stress of the day. You don't
need to worry about Joe Biden and Nancy Pelosi at
exactly that moment. You need to replenish. Drink water, Drink
more water, and when you're done, drink more water. After that,
(24:46):
get every ounce of sleep you can possibly get if
you don't have a comfortable mattress. Go see Mac. Mac
lives off the fact that people want to get better sleep,
and for good reason, because good sleep is critical your
good health. That's all I got on sleeping the moment, Oh, magnesium.
Magnesium allows me to sleep better than anything else.
Speaker 3 (25:15):
Side.
Speaker 1 (25:23):
If you compliment your friend or your friend's wife as
to them looking great. They've lost weight. What are you doing?
Are you working out? Are you intermittent fasting? You look fantastic.
Somebody who's been carrying an extra twenty or sixty pounds
(25:44):
for a very long time, all of a sudden has
a little spring in their step. And it's not just women.
Men carry themselves differently. When they've dropped down three, four
five sizes in their jeans, they start tucking their shirt in.
Oh my goodness, instead of tennis shoes with their genes,
they're wearing loafers, they're wearing dress shoes. They're all of
(26:06):
a sudden getting their hairstyled. It's a change in your
entire presentation. You can see the swagger in people. They've
been married for twenty five years and now all of
a sudden, they're acting like they used to when they
wooed their lover. Well, ozimpic is often the answer. And
I can't pronounce the word. I'll get the pronunciation. It's semiglitudes.
(26:28):
I'm not sure how you pronounce it. But our expert.
We went searching for an expert, and some of you
will know we have talked about this subject before. We
have had other doctors on to talk about this, but
it is such a common phenomenon, cultural trend and a
medical issue, and you know, I'm fascinated by those that
we are having an expert on the matter with us today.
(26:51):
Her name is doctor Archin Nosadu. She is a Board
certified endocrinologist specializing in diabetes and she is the director
of the System Diabetes Program at Houston Methodist. She is
specifically with us to talk about that diabetes drug. It's
actually being used as a diet drug causing some problems
(27:13):
for diabetics who really need the drug. Doctor Sadou, First
of all, why are we hearing ozimpic all the time?
What is so special about this drug?
Speaker 4 (27:25):
Well, thank you for having me here today, Michael. And yes,
it's all over the headlines and it seems to be
something new each time, but it actually it's been in
our toolbox for many years for type two diabetes, which
is what it was originally studied and approved for, because
it really lowered patient's blood sugars dramatically. But in those
(27:47):
studies it was also noted that they had a significant
weight loss. So then subsequently that drug semaglutide was studied
for just weight loss, so people without the diagnosis of
diabetes and again proved itself to be a great drug
to help people lose weight, and then it got FDA
(28:09):
approval for that indication. The drug is the same which
is semaglue hide, but for diabetes it's the brand name
is ozempic, and then for weightless alone it's called Wagovy.
So I think we're everyone's just kind of used to
the first name ozempic, but that's why we hear the
(28:29):
term ozempic all the time. But it could be either
ozempic or with goovy, which is the same drug.
Speaker 1 (28:36):
I want to talk about the differences between that and
why it's marketed separately because that's important for pharmaceutical REGs.
But first explain to me, like I'm in about seventh grade,
what exactly does ozempic or WEGOV do.
Speaker 4 (28:53):
So. Ozempic or the drug semaglue hide is a replica
of a hormone and we have naturally in our gut system,
which is called GLP one, And this hormone is secreted
as soon as we eat something, and it has several duties. Naturally,
(29:14):
one it delays the emptying of the stomach, so food
comes in lower, slower and gets absorbed more efficiently with
balancing the glucose that's being absorbed so that our blood
sugars don't get too high. And two, it also raises
the pincreas's ability to secrete insulin, again balancing blood sugars,
(29:39):
which is where its first effect was most exciting. But
third effect, which was unexpected, was that it actually also
works on the appetite center in the brain to decrease appetite.
And this all makes sense, right, So whenever we eat,
we want to feel full, we want to balance the
nutrients we're absorbing, and then we want to stop eating,
(30:01):
so we just don't keep eating all the time. So
this drug is there for those purposes. And what we've
done is in this synthetic version semagluetide, and there's others
just like it as well. This is just one brand
we've We've given it in a subcutaneous injection form at
(30:22):
much much higher levels than what our gut normally secretes
to enhance these effects of decreased appetite and what you're lowering.
So that's that's how the drugs are working.
Speaker 1 (30:35):
Let's take those one by one. But before we do that,
you said Ozimpic and Wigov are just one brand? Are
there other products out there? It sounds like you're loyal
to or partial to ozimpic. There's Manjara or something like that.
Are those all, as I understand it, they're all semi
(30:56):
glue tide semiglue tides. Are they all about the same?
Is there a reason you prefer ozimpic.
Speaker 4 (31:03):
Well, it's not about preference. So a little bit about
the history. The first drug of the class was actually
a totally different drug called exenotide, but the brand name Baieta,
and that was the very first version of this whole class. Subsequently,
we got loraglatide or also called victosa or sexenda, and
(31:28):
then the most recent one a semiglutide or ozempic, and
regovi really got attention because these were weakly injectable, so
much easier to use, much more tolerable for patients, and
so they gained in popularity. Munjaro is a brand new player,
which is terzepetide. It's another compound entirely, and it is
(31:54):
one step above ozembic even because it combines two hormones
that are secreted in our gut, whereas previously it was
just the gop one that I mentioned to eppetiteer. Manjaro
also adds GIP and not to confuse you or the audience,
but we're actually building even more on these gut hormones
(32:16):
in upcoming drugs. So they're all very they're all different,
although do the same thing in our digestive tracks and
the brain to have the end outcome be eating less,
balancing your blood sugar and weight box.
Speaker 1 (32:33):
All right, I'm going to hold you right there for
just a moment. We're talking to doctor Archinas Sadu spelled
sad Hu is the board certified into chronologists and hormones
and she specializes in debut He is the director of
the System Diabetes Program at Houston Methodist and we'll continue
(32:54):
our conversation with her coming up
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