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October 10, 2019 21 mins

CBD is everywhere: You can buy CBD olive oil, CBD mascara, CBD supplements for your dog- even CBD tampons! Some swear it alleviates everything from insomnia to chronic pain, anxiety and depression. But is it everything it’s cracked up to be? Or is it just the latest fad? Katie weeds out CBD fact from fiction with a little help from Kristen Bell, a CBD devotee, Rob Rosenheck, co-founder of Hollywood’s favorite CBD brand, and Dr. Yasmin Hurd, the country’s leading CBD researcher. She even samples some CBD products—for science!—and shares her thoughts about the experience.

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Episode Transcript

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Speaker 1 (00:00):
Next Question with Katie Curic is a production of I
Heart Radio and Katie Curic Media. Hi everyone, I'm Katie Kuric,
and welcome to Next Question, where we try to understand
this complicated world we're living in and the crazy things
that are happening by asking questions and by listening to
people who really know what they're talking about. At times,

(00:21):
it may lead to some pretty uncomfortable conversations, but stick
with me, everyone, let's all learn together. From your local
pharmacy to stores like Neiman Marcus and Sephora, it seems
you can't go anywhere these days without seeing or hearing
something about c B D phobe D is everywhere, d

(00:45):
C D oil phoebe D sold here. Celebrities like Amy
Schumer and athletes like soccer star Megan Rapino and golfer
Bubba Watson say it helps with everything from anxiety to
nausea to soar my soles. You can even walk into
your local bed, bath and beyond and find CBD for

(01:06):
that's right, your dog. It comes in oils, lotions, bath bombs, pills,
even gummies. And I actually tried a few products prepping
for this podcast. They smell a little like perfume. Let
me try one O. They taste a little like perfume. CBD,
which stands for is a chemical derived from the marijuana plant,

(01:29):
But unlike THHC that's another chemical found in marijuana, it
will not get you high. So my next question why
is CBD suddenly everywhere? And perhaps most importantly, does it
really work? A lot of celebrities these days are jumping

(01:51):
on the CBD bandwagon. Kristen, Hi, you are so sweet
to do this. I'm sorry, I know it's been such
a bear to schedule, but thank you so much. Oh
my god, of course I'm so happy to That's actress
Kristin Bell who's talked a lot about using CBD for

(02:12):
her anxiety. So why did she turn to it and
what is it doing for her? Kristen, when did you
start using CBD? I guess I started about two and
a half years ago. And what prompted you to start it?
You know? I had short of been hearing about it
for a while, and it was originally recommended to me

(02:37):
because my friends who were going on like red carpets
and wearing a high heel for a long time, had
this bomb with CBD in it that they were rubbing
on their ankles to save their feet. And I looked
into this company that made the ball most called Lord Jones,

(02:57):
and I noticed that they had a tincture. And I
noticed at a lot of people online had been saying
that it helps with anxiety because it generally has a
calming effect, and I am a very anxious person. You
noticed a real change, How did it make you feel?
And did it take a while for you to notice
the effects. It was like nothing I had ever tried. Okay,

(03:19):
so I did not notice it immediately. But what I
noticed about after the first I don't know, week or so,
when I drive home from work because I raised two
little girls, I'm on my way home from work going
through Okay, I need to remember to buy a new
lunch pail because that one got stinky. Or I need
to remember to replace the apples because they'll have no

(03:41):
apples for their lunches, like all these silly little things
like you know so and so neat the dentist appointment,
And I'm just going through this sort of mental frantic
list on my way home to get back into mom mode.
And about after the first week, I noticed I was
just enjoying the radio and I wasn't finding myself any
less efficient at home. The dentist appointment was still being made,

(04:03):
the lunch pail will still be going to ask you
who bought the apples. It was still me. It wasn't
a laziness at all. It was simply a slightly calmer
version of me that didn't need to worry frantically in
order to complete a task. Did I notice the effects
right away, No, because there's nothing that you can feel.

(04:24):
But what I did notice is I wasn't having these
about these sort of targeted bouts of anxiety when I
was alone, like in my car, and that's when it
hit me. I was like, oh, this is working for me.
Do you ever wonder, Christian, that it might be a
placebo effect? You know, I do think about that a lot, actually,
because I feel like I would be a candidate for pebo,

(04:48):
to be honest. Um. But I have tried a lot
of things. I mean I I've tried and I like
taking adaptagen sometimes for my anxiety. I've tried like every
little supplement or vitamin that comes on the market, and
I haven't noticed as much of a worry free Christen
as I do with CBD. You know, I know, Christen,

(05:12):
you've also been open about the fact that you like
to smoke plot occasionally. Is there a difference in terms
of the results? Oh, A bajillion degree of difference like this,
Taking CBD you have you are fully functioning. You can
drive your car, you can make a science project with
your child, you can you know, take the l sets,

(05:35):
you can do whatever. There is nothing that messes with
your brain. You feel completely and utterly like yourself. You're
just breathing a little easier and with THHD when you
take something that has C HC and CBD, when you
use a vape or take a gummy or you know,
smoke a joint or something that has an effect on
your mind, and that world is totally different now from

(05:59):
the BBD world. And I, to be honest, like both.
But I'm clearly am raising two children. I'm not smoking
pot every day, you know what I mean? And before
we go, I just wanted to ask you, why do
you think this is such a hot trend right now?
Why do you think that everywhere you look, at least
for me, you've just see C B D a couple

(06:23):
of things. I think that speaks to a lot of
people speaking highly of it and seeing results. I don't
think something that's a snake oil gets this much heat
around it. I also think we are in a state
as humans where there is a lot of depression and
anxiety going around. People are going really fast. We have

(06:44):
our phones. We've been going at such a fast pace
as human beings. We are requiring things that calm us.
And for people that don't want to drink or do drugs,
this much like mindfulness is a very easy, simple effective
for me solution to being less anxious during the day.

(07:08):
It worked for Kristen Bell, but that doesn't necessarily mean
it works for everyone. I decided to try some CBD
products myself, and I got a boatload of them to
prepare for this episode. I even got my husband, John
Mulner involved and made him try a CBD cream for
his aching feet. I did my left foot because my
left foot typically bothers me more than my right foot,

(07:31):
and so I just put some of that CBD cream
on my left foot and it felt pretty good this morning.
It didn't ache really, and it sometimes aches in the morning. Yeah,
you can do it. You're going to try it again.
I would try it again. Now I've been walking around
for a few hours and it's a little it's a
little laky, but um, it felt pretty good this morning,
and because it was morning, I decided to fix myself

(07:53):
a Friday. Did you know they even have c D
d olive oil. I also tried some CBD drops by
this tincture peppermint, and it says high cb D. Place
one full dropper under the tongue hold for sixty seconds
and then swallow. I've got a full dropper full um

(08:17):
under my comp I have to be honest, I didn't
really notice a big difference. Having said that, I'm not
sure I used it regularly enough for it to have
an effect, but clearly it is helping a lot of people.
And I wanted to understand why We're gonna take a
quick break here. We'll be back in a minute to

(08:40):
weed out CBD fact from fiction. Get it weed out.
I reached out to the go to woman for all
things CBD, Dr Yasmine heard she's the director of the
Addiction Institute at Mount Sinai and a professor of psychiatry, neuroscience,
and pharmacological sciences. I asked her to explain and layman's terms,

(09:02):
how CBD works. Understanding how CBD works is also challenging
for scientists. Many people are trying to figure out how
it works. We do know that it is a molecule
that's a cannabinoid that's found in the cannabis and hemp plants,
and it binds two receptors in our body and brain

(09:24):
that are regulating different transmitter systems. And what I mean
by that is that it will change the activity of
cells in different parts of the brain. So t HC
is a psychoactive component on the cannabis plant. That's why
people get the high. The intoxication that binds to the

(09:45):
cannabinoid receptors in our brain and our body. CBD actually
doesn't bind to those receptors that cause the intoxication. But
what it does is that it tweaks different neuro transmitter systems,
So it will turn up one transmitter system and turn
down another so that it stays in homeostasis in a way.

(10:07):
So neurotransmitters are responsible for things like pain or anxiety
or depression exactly, and CBD will alter those transmitter systems
that are involved in many different functions as you said, pain, mood, anxiety.
So it has a broad mechanism of action and that's

(10:30):
one of the things that's been fascinating and frustrating for
the scientists, and that's why we all can figure it
out completely. CBD has been shown to be really effective
in a in a couple of very important areas. What
are those. One of the disorders absolutely that is clear
from clinical trials is childhood epilepsy seizure disorders. So these

(10:53):
caesar disorders such as travaise, CBD is now an f
D approved medication for them. So that has think significantly
moved the field in believing that CBD has medicinal properties.
What about opioid addiction. I know there's exciting research that
you've done about that. We have conducted small clinical studies

(11:14):
that have shown that CBD decreased craving in people who
have an opiate use disorder. It decreased their anxiety related
to their craving as well, which are two key features
for why people relapse. So we're now going to start
a large clinical trial and we'll see whether or not
it replicates. But a lot of the work not only
from our group but from others, have now started to

(11:36):
show that CBD does have potential to decrease craving and
opioid users. So those are two very very exciting areas
and that should counter this notion that it's just snake oil. Right, Absolutely,
CBD is not snake oil. There are people trying to
make it snake oil in promising that it can change

(11:59):
every single thing in our society. Clearly, it seems CBD
holds a lot of promise for a variety of conditions
and that's not lost on people who are hoping to
cash in. And no wonder, the market is projected to
reach twenty billion with the b BY So what is

(12:21):
your concern about this growing industry and the fact that
it's being sold in so many different forms for so
many different problems. The fact that you can buy CBD
on your steak, in your coffee and water, even mess
Gara their CBD mascara, theres CBD mascara, and sadly there's
also CBD tampons. The problem is all of this lends

(12:45):
itself to many people thinking CBD is a snake oil,
because how can one thing help with all of these
different syndromes, disorders, even recreational quote unquote benefits. It can't.
It's a fat like any thing else. So that many
people are just trying to make money without ever having
to prove that their CBD messcara works. They don't have

(13:08):
to do that. They are just riding the wave of
CBD being a fed and wanting a part of that
industry because, like you said, it's gonna be billions of
dollars for me. That does trivialize the potential medicinal properties
that CBD is showing to have. So I want the
public to understand that there may be quote unquote snake

(13:31):
oil components out there regarding CBD that's very separate from
the promise that CBD does show. So dr heard, what
do you say to consumers? How do you know what works,
what doesn't, what's worth trying, what's not? How much is
too much to spend on these products? Well, the month
do you want to spend is going to be up

(13:51):
to you, Like I said, of fact, that someone will
pay fifty dollars for our coffee, you know, that's up
to them. However, for me, in terms of safety, that's
the thing that's the issue. Right, So many people are
consuming CBD and don't even know where it comes from,
so they don't know if CBD is really in the
product they've done studies where they have shown that the

(14:12):
amount of CBD that's actually in the product that's compared
to the label don't match, and in fact those products
might even contain things like lead and pesticides. So the
public needs to be aware. They have to do their
due diligence because now everybody and their mother is getting
into the CBD industry because of being a fat and
the profits that are there, So it is not as

(14:35):
regulated as it should be, and I think the FDA
they're starting to consider what types of regulations that will
be needed for CBD. Why isn't it regulated? I don't
think that the FDA realized how fast this was going
to explode and that they needed to be ahead of
this wave rather than behind it. So they're now catching

(14:57):
up and will start making so sort of guidelines. I
absolutely think that no company should be allowed to say
that CBD can do X, Y or Z unless they
prove it. This seems like a good time for a break,
so we'll be back in a moment. Rob Rosenheck and

(15:20):
Cindy Capa Bianco are the husband and wife co founders
of Lord Jones, the CBD company. Kristen Bell mentioned Rob
told me they'd be happy to have more regulation because
consumers need to know that the products that they're buying
are safe, that they're manufactured in a safe way, that
they're properly labeled, that the dosage is accurate, just like

(15:41):
any other food or any other drug. People want a
regulated system. They want a set of rules to play by.
They want to be able to comply with regulations and
um and put out products that are safe. Robin Cindy
now run a multimillion dollar empire. They start it out
in medical marijuana, but soon found that the real gold

(16:03):
could come from another part of the plant. There was
this other count of ainoid we started to read about
called CBD, and it was associated with all of these
health and wellness benefits, and we became obsessed with it,
and then we started to experiment, and so the first
thing we did was make combinations of CBD and th
HC and so our most popular product was this five
to one ratio, so it had five parts of CBD

(16:25):
to just one part of THHD, and we made that
both in skincare and in ingestibles, and it became our
most popular product formulation. We first introduced hemp derived CBD
only products, so they were our same formulations of skincare
or confections, and we made those available in two thousand seventeen,
and in one month the business grew larger than our

(16:47):
entire THHD business, and we realized that was our future.
Why do you think this CDD business and market has
absolutely exploded? They're basically two reasons for it. The first
is the whole legalization movement of cannabis, So that's been
happening for twenty years, and more consumers are aware of it,

(17:07):
more consumers are in favor of it. A majority of
Americans have access to some form of cannabis in the
state that they live. A majority of Republicans are in
favor of legalization. That truly is an issue that unites us.
And the second piece is the passage of the two
thousand eighteen Farm Bill. So it made these products available
at the same time that people were curious about them,

(17:28):
and that opened up the floodgate. You sent me some samples,
but wow, your products are expensive. Your gum drops cost
fifty a pack, your oils cost up to a hundred bucks.
Could chang rob CBD is an expensive ingredient if you
look at all of the CBD products that are out there,

(17:49):
ores are actually comparably priced. There's a couple of things
that consumers should be aware of, their different kinds of
CBD and different methods of extracting CBD. So when you
grow hemp plants, you get this giant plant. There's a
lot of biomass, but you only get a very tiny
amount of CBD from that plant. And supply and demand

(18:11):
it is, and we don't have enough supply of hemp
right now to provide the demand for CBD. But when
you extract it, you only get a little bit, so
it's an expensive ingredient. The other thing is there's two
different main ways to extract CBD. You can extract the
oil from the plant, or you can distill it down
into what's called an isolate, which is just pure cbd.

(18:32):
It doesn't have the other turpenes and plant waxes and
constituent components of the plant. Isolate is a more refined
form of CBD that's cheaper and not as effective. So
you want to get either a full spectrum or a
broad spectrum oil that's sourced from domestically grown hemp, and

(18:52):
that CBD is more costly and that's why some CBD
products are priced higher. Meanwhile, Rob has been really open
about his depression and talking about what's helped him deal
with it. Can I ask you a personal question, of course,
how often do you use CBD and do you still

(19:13):
use cannabis for your depression or do you feel that
CBD has helped you enough. I do use CBD, and
I do use th hc U CBD every day. I
put it on my face, I do why. It makes
my skin feel nice, and I take it in the
evening to help you sleep, help me sleep sometimes. But

(19:35):
for your depression, you still feel still use cannabis regularly,
a couple of times a week. I really enjoy it.
It's legal now in California, and it takes the edge
off I don't drink alcohol, I don't smoke tobacco, but
I do enjoy cannabis. One thing is clear. We're very

(19:59):
much in the early days of CBD. But for those
who suffer from a whole host of problems from anxiety
to pain to addiction, and for people like Dr Heard
who are trying to help them, this new frontier offers
tremendous hope. What are you most excited about when it
comes to cb D. I'm actually most excited by the

(20:21):
fact that more researchers are getting into this so that
we will be able to finally tease out one how
CBD fully works and have more insight into what disorders
and symptoms it might be beneficial for. I am excited
because I'll start to conduct some clinical trials of our own,

(20:44):
really large ones that we just got a grant for
from the n i H National Institutes of Health, and
we'll finally know whether or not, in a large population,
does it really decrease craving in people with an opiate
use disorder? And that's exciting for me. Next Question with

(21:04):
Katie Couric is a production of I Heart Radio and
Katie Curic Media. The executive producers are Katie Couric, Lauren
Bright Pacheco, Julie Douglas, and Tyler Klang. Our show producers
are Bethan Macalouso and Courtney Litz. The supervising producer is
Dylan Fagin. Associate producers are Emily Pinto and Derek Clemens.
Editing is by Dylan Fagan and Lowell Berlante. Our researcher

(21:26):
is Barbara Keene. For more information on today's episode. Go
to Katie currek dot com and follow us on Twitter
and Instagram at Katie correct For more podcasts from My
Heart Radio, visit the I Heart Radio app, Apple podcast,
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Katie Couric

Katie Couric

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