HeadWise

HeadWise

A podcast about the latest news on migraine disease and headache disorders.

Episodes

September 9, 2026 21 mins

In this episode of HeadWise™, Dr. Alexandra Ross, a pediatric headache psychologist from Streamind Health, joins host Lindsay Weitzel, PhD, to share real strategies for the school year ahead: building routines that stick, using 504 plans for accommodations, sneaking in "micro breaks" during class, and helping kids talk about migraine without the stigma. This episode is for educational purposes only and is not intended to provide me...

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Meet Hope O’Brien, MD, MBA, the new president of the National Headache Foundation’s Board of Directors. In this episode of HeadWise™, Dr. O’Brien shares what led her to headache medicine, the challenges facing headache care today and her vision for the future of NHF.
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August 21, 2026 19 mins
What happens when headache, migraine-like symptoms or other symptoms persist after a concussion? In this episode, host Lindsay Weitzel, PhD, is joined by neurologist Shae Datta, MD, to discuss concussion, post-traumatic headache and the recovery process. They explore what to do after a concussion, when symptoms may require further evaluation and why headache can continue even after other concussion symptoms improve. They also dis...
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Nausea and vomiting are common symptoms associated with migraine, but they can look very different from one person to another. Some people experience mild nausea, while others may have vomiting that makes it difficult to eat, drink or take medication.

In this episode, host Lindsay Weitzel, PhD, is joined by headache medicine specialist Fred Cohen, MD, to discuss nausea and vomiting with migraine. They explore why these symptoms ma...

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July 29, 2026 22 mins
What role could psychedelics play in the future of headache medicine? In this episode of HeadWise, host Lindsay Weitzel, PhD, is joined by Emmanuelle Schindler, MD, PhD, to discuss the latest research on psilocybin and other psychedelics in migraine, cluster headache, and post-traumatic headache. They explore how these compounds are being studied, what early clinical trials have found, safety considerations, and why more research...
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In this episode of HeadWise™, host Lindsay Weitzel, PhD, is joined by Amelia Barrett, MD to explore how emerging research on biological pathways may help explain why some people experience treatment-resistant migraine. The conversation focuses on several actionable pathways involved in medication metabolism, methylation, and neurotransmitter function, and discusses how these processes may influence migraine, medication side effect...
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In this episode, host Lindsay Weitzel, PhD, is joined by neurologist Amelia Barrett, MD, to explore the role histamine may play in migraine and headache disorders. Dr. Barrett explains what histamine is, how it functions in the immune system, and why elevated histamine levels may contribute to headache attacks in some people. They discuss the connection between histamine, inflammation, mast cells, and migraine, along with common f...
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In this episode, host Lindsay Weitzel, PhD, is joined by headache specialist Fred Cohen, MD, to explore one of the most common questions people ask about headache disorders: What does it mean if my head hurts in a specific location?
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May 20, 2026 32 mins
In this episode, host Lindsay Weitzel, PhD is joined by Tim Smith, MD and migraine clinical trial participant Tierra Lillard to explore how migraine clinical trials help advance treatment options and improve care for people living with migraine.
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In this episode, host Lindsay Weitzel, PhD, is joined by neurologist Amelia Barrett, MD, to explore the role of tyramine in headache and migraine. They break down what tyramine is, how it affects the body, and why certain foods may trigger headache or migraine attacks in some people.

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In this week’s episode of HeadWise, Lindsay Weitzel, PhD, and Tim Smith, MD, break down the latest migraine research news. They discuss a new PACAP-targeting migraine treatment in development, research on exercise and migraine frequency, “false non-responders” to CGRP therapies, and new findings on THC/CBD and vaporized cannabis for migraine treatment. Listen now for a closer look at emerging migraine research a...
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Behavioral therapies can play a key role in migraine care. In this episode of HeadWise, Lindsay Weitzel, PhD, is joined by Dawn Buse, PhD, to break down approaches like cognitive behavioral therapy (CBT), biofeedback, relaxation training, mindfulness, and ACT. Learn how these strategies help regulate the nervous system, reduce symptoms, and improve quality of life for people living with migraine.
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Blood sugar may play a bigger role in migraine disease than many people realize. In this episode of HeadWise™, host Lindsay Weitzel, PhD, and guest Laurel Short, DNP, explore how blood sugar fluctuations, insulin, and meal timing may impact headache and migraine, along with simple strategies to help keep levels more stable throughout the day.
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In this episode, host Lindsay Weitzel, PhD, is joined by headache medicine specialist Fred Cohen, MD, director of Headache Intervention in New York City and assistant professor at the Icahn School of Medicine at Mount Sinai, to discuss why headache attacks commonly occur during viral illnesses like the flu, COVID, and other infections. They explore how inflammation and immune responses during illness can trigger headache attacks, ...
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In this episode, host Lindsay Weitzel, PhD, is joined by Sam Kelokates, PT, DPT, founder of Kelos Physical Therapy, to discuss how people living with migraine and other headache disorders can approach exercise safely and effectively. They explore how physical activity can both trigger and help prevent migraine, what the research currently shows, and how to build an exercise routine that supports long-term headache management. The ...
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In this episode, Laurel Short, DNP and host Lindsay Weitzel, PhD, break down the science behind aerobic exercise, strength training, and yoga—and how each can influence migraine frequency, intensity, and overall wellbeing. They also discussion the difference between primary exercise headache and migraine, and why it’s important to talk with a healthcare provider when head pain is triggered by physical activity. You&rs...
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In this episode, host Lindsay Weitzel, PhD, is joined by Dr. Dawn Buse, a psychologist specializing in headache and migraine, and Katie Oakley, who shares her personal journey living with chronic and post-traumatic headache. Together, they explore the role of behavioral therapies in migraine care and how these approaches can support prevention, quality of life, and safer treatment options for people living with migraine—both...
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In this episode of HeadWise™, host Lindsay Weitzel, PhD, welcomes Katy Oakley, the new Chief Executive Officer of the National Headache Foundation (NHF). Katy shares her personal journey living with post-traumatic headache and chronic migraine following a traumatic brain injury in her twenties and how years of daily head pain, delayed diagnosis, and difficulty accessing care shaped her path to leadership within the headache commun...
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In this episode of HeadWise™, host Lindsay Weitzel, PhD, talks with headache specialist Fred Cohen, MD, about the viral migraine remedies circulating on TikTok, Instagram, and social media — and whether any of them are actually helpful. Together, they break down popular home remedies and “migraine hacks,” explaining which approaches may offer real relief, which lack evidence, and which could potentially cause har...
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In this episode of HeadWise™, host Lindsay Weitzel, PhD, talks with Vincent Martin, MD—director of the Headache and Facial Pain Center at the University of Cincinnati—about a foundational and evolving question in headache medicine: Is migraine a systemic disease? Dr. Martin explains why migraine is not always a single neurological disorder and how emerging genetic and population-based research is revealing that only ab...
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