Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals

Amar Krishnaswamy, MD, and Marijan Koprivanac, MD, discuss contemporary follow‑up strategies after TAVR and SAVR, highlighting advances in minimally invasive and robotic surgical approaches that significantly reduce recovery time and postoperative pain. They outline evidence‑based recommendations for cardiac rehabilitation and structured imaging surveillance, emphasizing the critical role of timely follow-ups to detect early valve‑...

Explore the latest ACC/AHA guidelines on acute coronary syndromes with co-authors Venugopal Menon, MD, and Jacqueline Tamis-Holland, MD, joined by Donna Kimmaliardjuk, MD. This discussion covers key updates, including unified STEMI/non-STEMI recommendations, heart team decision-making for multivessel disease, evolving strategies for dual antiplatelet therapy, and the role of mechanical circulatory support in complex cases.

Stanley Hazen, MD, PhD, and Scott Cameron, MD, PhD, discuss emerging evidence linking gut microbiome-derived TMAO to abdominal aortic aneurysm development and progression. They explore its role as both a causative factor and a biomarker, review current risk stratification strategies and highlight future therapeutic approaches aimed at reducing TMAO levels to improve vascular outcomes.

Learn more about the research. https:/...

Hani Najm, MD, and Joanna Ghobrial, MD, discuss the evolving role of transcatheter pulmonary valve implantation in lifetime management of congenital heart disease patients. They explore patient selection, valve durability, imaging strategies for early detection of HALT or HAM and the collaborative heart team approach that optimizes outcomes.

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Venugopal Menon, MD, Director of the Coronary ICU, and Michael Tong, MD, cardiothoracic surgeon specializing in advanced heart failure, discuss contemporary management of post-infarction ventricular septal rupture, a rare but serious complication. They review the role of early transfer to high-volume centers and why definitive surgical closure remains the gold standard. Learn about the impact of temporary mechanical circulatory sup...

Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinical trials aimed at improving post-tr...

Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to identifying and managing cardiovas...

Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved outcomes.

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Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and emerging clinical trials.

Rea...

Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.

Learn more about C5 Research at Cleveland Clinic.
https://my.clevelandclinic.org/research/c5research...

A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes. 

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Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease.

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Tamanna Singh, MD, and Amanda Vest, MBBS, discuss the relationship between obesity and heart failure. They discuss multidisciplinary strategies, including lifestyle interventions and pharmacologic therapies like GLP-1 receptor agonists for managing patients across the spectrum of heart failure. Learn emerging clinical research regarding obesity and heart failure from Cleveland Clinic experts. 

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When a heart is weak after a heart attack, cardiac arrest or surgery, mechanical circulatory support (MCS) can help the heart function while it heals or assist patients long-term.  Cleveland Clinic experts discuss MCS devices, specifically the Impella percutaneous left ventricular assist device (LVAD) and extracorporeal membrane oxygenation (ECMO).

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Amanda Vest, MBBS, explores sex-based differences in heart failure, focusing on biological and social factors that influence disease development, treatment response and outcomes in women. She highlights disparities in risk factors, access to care and clinical trial representation that can influence heart failure outcomes. 

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p...