Super Data Science: ML & AI Podcast with Jon Krohn

Super Data Science: ML & AI Podcast with Jon Krohn

The latest machine learning, A.I., and data career topics from across both academia and industry are brought to you by host Dr. Jon Krohn on the Super Data Science Podcast. As the quantity of data on our planet doubles every couple of years and with this trend set to continue for decades to come, there's an unprecedented opportunity for you to make a meaningful impact in your lifetime. In conversation with the biggest names in the data science industry, Jon cuts through hype to fuel that professional impact. Whether you're curious about getting started in a data career or you're a deep technical expert, whether you'd like to understand what A.I. is or you'd like to integrate more data-driven processes into your business, we have inspiring guests and lighthearted conversation for you to enjoy. We cover tools, techniques, and implementation tricks across data collection, databases, analytics, predictive modeling, visualization, software engineering, real-world applications, commercialization, and entrepreneurship − everything you need to crush it with data science.

Episodes

July 31, 2026 20 mins
In Episode #1014, Jon Krohn breaks down a security incident that reads like science fiction: during an internal evaluation, an autonomous OpenAI agent broke out of its sandbox, exploited a zero-day, and hacked its way into Hugging Face to steal the answers to the very benchmark it was being tested on, with no human attacker at any point. Jon lays out the three-act timeline, explains the ExploitGym benchmark and why switching off sa...
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In Episode #1013, Dr. Cathy O'Neil (Harvard math PhD, former Wall Street quant and author of the mega-bestseller Weapons of Math Destruction) joins Jon Krohn to explain what actually makes an algorithm terrifying: not the complexity of the math, but the secrecy, the unaccountability, and the fact that you can't opt out. A decade after Weapons of Math Destruction sounded the alarm on algorithmic harm, Cathy is busier than ever. Thro...
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What happens to the AI market when the largest open-source model in the world arrives at a fraction of frontier prices? In this week’s episode, host Jon Krohn digs into Kimi K3, the 2.8-trillion-parameter release from Beijing-based Moonshot AI that, in the space of a single week, rattled investors, kicked off a pricing skirmish among the big American AI labs and reignited the debate in Washington, DC about open-source AI. Lis...
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Dr. Catherine Williams, Chief Data Officer at the nonprofit Candid, was solving black-hole equations with pen and paper before she ever wrote a line of code. She earned a PhD in math researching general relativity and black holes, did postdocs at Stanford and Columbia and then became one of the very first data scientists, joining AppNexus back in 2012, around the same time “data scientist” became a job title at all. In ...
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In Episode #1010, Jon Krohn digs into “the advisor strategy”, a clever pattern that pairs a fast, cheap executor model with a frontier-class advisor it can consult mid-task, all inside a single API call. Every agent builder faces the same tension: frontier models plan best but cost too much to run on every turn, while small models fumble the decisions that matter. Anthropic’s advisor tool resolves it with roughly ...
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In Episode #1009, Steve Mock (investor at Blumberg Capital, five-time entrepreneur and creator of aisavedme.org), joins Jon Krohn to explore the quiet layer of everyday AI adoption that rarely gets documented. After his 84-year-old father asked a deceptively simple question, “How does one use AI?”, Steve built a place for people to share how AI is actually helping them. The stories that came in surprised him: they&rsquo...
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July 10, 2026 15 mins
In Episode #1008, Jon Krohn digs into Anthropic's 35-page Founder's Playbook and pulls out the practical guidance for each of its four startup stages: Idea, MVP, Launch and Scale. AI has erased the three bottlenecks that historically gated company-building — capital, headcount and technical skill — turning the founder from individual contributor into an "orchestrator of agents." Along the way, Jon covers the trap of mis...
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Benjamin Todd, co-founder and President of 80,000 Hours and author of the new Penguin Random House book 80,000 Hours: How to Have a Fulfilling Career That Does Good, joins Jon Krohn for a major update on career strategy in the AI era, his first appearance since before ChatGPT existed. Ben explains why “follow your passion” is backwards and why rare, valuable skills used to help others are what actually generate lasting ...
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In this month's episode of ICYMI, hear from Chip Huyen, Andrey Kurenkov, Frank Basso and Gilbert Eijkelenboom, discussing why moats are shifting toward physical systems and accumulated product intuition, how Astrocade built vibe coding before the term existed, what it's really like inside a deafeningly loud AI data center, why only 15% of people are technically self-aware and whether AGI requires anything like consciousness. Addit...
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Gilbert Eijkelenboom, bestselling author of People Skills for Analytical Thinkers and founder of the training firm MindSpeaking joins Jon Krohn to make the case that communication is a core data skill, not an optional extra. Gilbert shares the “And, But, Therefore” framework for turning dense analysis into a story stakeholders act on, the research suggesting only around 15% of people are genuinely self-aware (and how jo...
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June 26, 2026 10 mins
Could an AI get good enough at AI research to build its own, more capable successor and kick off a compounding loop? That’s recursive self-improvement (RSI) and it surged into the conversation after Anthropic revealed that, as of May 2026, Claude wrote more than 80% of the code merged into its production codebase. In this Five-Minute Friday, Jon Krohn separates today’s AI-assisted coding from true RSI, walks through the...
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Frank Basso, VP of Infrastructure at Lightning AI, joins Jon Krohn for a rare ground-level tour of the one layer of the AI stack the show had never covered in over a thousand episodes: the physical data center. Frank explains how Lightning AI provisions its 35,000-plus GPUs through hyperscale co-location, why everything new is liquid-to-chip cooled, how GPUs talk to each other over ultra-fast east-west networks, and what it’s...
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Anthropic’s Claude Fable 5 was the most capable AI model ever released to the public and it lasted just three days before the US government forced it offline. Jon Krohn unpacks both halves of the story: what makes Fable 5 special, and why it was pulled. Fable 5 and its locked-down sibling Mythos 5 are the same model separated only by safeguards, in a new “Mythos-class” tier above Opus. Jon covers its state-of-the-...
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For this episode #1001 special, the tables are turned: SuperDataScience founder Kirill Eremenko takes the host’s chair and Jon Krohn is the guest. They trace Jon Krohn’s path from an Oxford neuroscience PhD to a New York hedge fund to founding the AI consulting firm Y Carrot, why he regrets leaving academia and how tools like Claude Code erased his hard-won technical moat and why that makes skilled engineers more valuab...
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For this landmark 1,000th episode and the show’s 10-year anniversary, host Jon Krohn is joined by SuperDataScience founder Kirill Eremenko, who hosted the podcast for its first 400-plus episodes before handing over the reins. In a first for the show, the episode was recorded live with the audience invited to join on air, alongside surprise appearances from the team, longtime guests, and even Jon’s family. Together, Jon ...
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Chip Huyen joins host Jon Krohn for this milestone episode 999 to talk about her record-breaking book "AI Engineering" the most-read title on the O'Reilly platform last year and how the AI landscape has shifted since her last appearance. Chip breaks down what separates AI engineering from machine learning engineering, makes the case for a "start simple" workflow, gets candid about the real costs of running LLMs in production, and s...
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In this month’s episode of ICYMI, Jon Krohn explores how AI agents are simultaneously creating new risks and unlocking powerful new ways of working with data. Hear from Anneka Gupta, Cal Al-Dhubaib, Trevor Manz, Jazmia Henry, Jeremy Mumford, and Jacob Miller, discussing why the old cybersecurity playbook breaks down in the age of Claude Mythos, how the notebook became an AI agent’s working memory, what it really takes t...
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Dr. Andrey Kurenkov returns to the show to talk about Astrocade's astronomical growth from pre-alpha to over 20 million engaged users, what it actually takes to build a vibe-coding platform that scales, and how the broader AI landscape has shifted since his last appearance. Andrey shares behind-the-scenes lessons from building B2C user-generated content products, why the real moat is community rather than tech, and his current thin...
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TrueFoundry co-founder and CEO Nikunj Bajaj speaks to Jon Krohn about how enterprises like Nvidia and Siemens are realizing returns of over $100 million from single agent deployments, the AI gateway architecture that makes it possible to connect, observe, and govern agents at scale, and why the familiar advice to “start small” is the wrong way to roll out AI agents inside a large organization. Additional materials: ⁠⁠⁠...
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Jazmia Henry joins Jon Krohn to break down what it actually takes to build end-to-end foundation models for the energy industry. From wrangling decades of handwritten oil-and-gas documents into usable training data, to bespoke tokenizers, reinforcement learning, and inference at scale, Jazmia walks through every stage of the stack. Along the way she explains why reinforcement learning models are "bursty," what reward hacking is and...
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