Metabolic Mindset

Metabolic Mindset

Metabolic Mindset is a science-backed podcast that breaks down metabolic physiology into simple, practical strategies you can actually live by. Hosted by dietitian Shara Perry, each episode cuts through nutrition dogma and teaches you how to fuel, train, and live for better energy, hormones, and long-term health.

Episodes

April 13, 2026 71 mins

In this episode of Metabolic Mindset, I’m joined by Zane Griggs (@zanegriggsfitness), a long-time personal trainer and host of the Healthy AF Podcast. Zane and I met years ago when we were both deep in the low carb world. Since then, we’ve independently shifted toward a more pro-metabolic, physiology-first approach to nutrition and training.

This conversation is about what actually works for our clients.

We break down why restrictive...

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Taurine is one of the most misunderstood nutrients in modern nutrition—often associated with energy drinks, but rarely understood for what it actually does in the body.

In this episode of Metabolic Mindset, I discuss the physiology of taurine and why it plays a critical role in metabolic health. From cardiovascular function and calcium signaling to nervous system regulation, electrolyte balance, and bile production, taurine supports...

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In this episode of Metabolic Mindset, Registered Dietitian Shara Perry breaks down why more exercise isn’t always the answer for fat loss. Chronic high-intensity training, under-fueling, and elevated cortisol can actually stall fat loss by breaking down muscle, lowering metabolic rate, and signaling the body to hold onto energy. Shara explains the physiology behind Zone 1 and Zone 2 cardio, how they support mitochondrial health, fa...

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Most supplements on the market don’t actually support your metabolism. In this episode, I break down which supplements are truly worth your time—covering multivitamins, magnesium, electrolytes, vitamin E, creatine, and glycine—and how they support energy production, thyroid function, fat loss, and overall metabolic health. I also explain which popular supplements, like fish oil and pre/probiotics, may actually interfere with metabo...

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Episode 5 – The Randle Cycle: A Physiology-Based Explanation of Fuel Competition and Energy Efficiency

Why do so many people feel better when they reintroduce carbohydrates — yet can’t explain why?

In this episode of Metabolic Mindset, I break down the Randle Cycle, a core concept in metabolic physiology that explains how fat, protein, and carbohydrates compete for oxidation at the cellular level. You’ll learn why high fat intake can...

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In this episode of Metabolic Mindset, we go beyond calories and macros and dive deep into the physiology of chronic dieting and metabolic adaptation. You’ll learn exactly how prolonged calorie restriction alters thyroid function, leptin signaling, cortisol output, mitochondrial efficiency, muscle metabolism, and fat tissue behavior — and why these adaptations make fat loss increasingly difficult over time. This episode explains, at...

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In this episode, we break down why fat loss can stall even when calories are controlled and workouts are consistent. You’ll learn how cortisol, thyroid signaling, fuel availability, and recovery determine whether your body burns fat or holds onto it—and why eating less is often not the answer.

Support the show

Work with me at Nourish (covered by insurance, often $0): https://www.usenourish.com/providers/shara-perry?referralSource=Nou...

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In this episode of Metabolic Mindset, I break down how to calculate calories and macros using a pro-metabolic framework. You’ll learn how to estimate true maintenance calories, adjust intake for fat loss, maintenance, or muscle gain, and set macros in a way that supports energy, hormone health, and metabolic resilience. I cover why protein anchors the system, carbs fuel the metabolism, fats stay moderate, and how carb tolerance exp...

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December 3, 2025 13 mins

What is a pro-metabolic diet, really?
In this episode, Shara breaks down the physiology behind metabolism, why so many mainstream nutrition messages backfire (like “eat less, move more” and “carbs slow your metabolism”), and what it actually means to support the thyroid and mitochondria. You’ll learn the core principles of a pro-metabolic approach, why carbs and minerals matter, and how to start fueling your body without extre...

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