Practical AI

As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security framework and what it means for organizations deploying agentic systems. They examine the key security risks facing agentic systems and discuss how organizations can apply Zero Trust principles to deploy AI agents safely. Along the w...

AI models can win math olympiads… but still struggle to read an analog clock. In this fully connected episode, Dan and Chris break down the latest Stanford AI Index Report and explore what it reveals about the current state of AI. They discuss AI adoption and safety, disappearing junior tech jobs, robotics, AI’s “jagged frontier” of intelligence, and the growing race between the U.S. and China. Along the wa...

What happens when AI agents start acting less like chatbots and more like coworkers? In this episode, Dan and Chris sit down with Craig McLuckie, CEO of Stacklok to explore MCP, Kubernetes, ToolHive, enterprise AI, and the emerging infrastructure powering AI-native applications. From identity management to agent orchestration and system architecture, this conversation dives into how organizations may soon manage entire fleets of AI...

Open Source AI is entering a new era, one shaped by self-improving AI Agents, recursive learning systems, and rapidly evolving AI Tools that blur the line between software and autonomous collaborators. In this episode, Daniel and Chris sit down with Nous Research co-founder and CTO Jeffrey Quesnelle to explore Hermes Agent. Along the way, they discuss models vs. harnesses, the changing role of developers, and one of the biggest que...

U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world.  Blending political savvy and statesmanship with his unique technical understanding as an active Ph.D student in AI at George Mason University (making him the coolest member of Congress!), the congressman shares his perspective about the really hard AI ...

In this fully connected episode, Dan and Chris break down one of the biggest questions in AI today: do open vs. closed models still matter? From the rise of physical AI and edge devices to the shifting landscape of open-source models like LLaMA, they explore whether the “model wars” are becoming irrelevant. The conversation then dives into a bigger transformation, the rise of agentic systems, workflows, and AI-driven in...

In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible implications from "We've been here before. 🙄" to "See ya, cybersecurity! 😱"  It's the end of the world as we know it, and I feel fine. 🙃

Then they have fun with the craziest AI announcement of the year (except for the Mythos one of course)...

Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma AI, to explore how OpenPilot is bringing self-driving to everyday vehicles using open source AI. We dive into the intersection of machine learning, robotics, and simulation, including how world models are enabling training at scale and s...

In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore how the open source community is responding and why this moment could reshape how AI systems are built and secured.

Featuring:

• Chris Benson – Website, LinkedIn, Bluesky, GitHub, X
• Daniel Whitenack – Website, GitHub, X

U...

AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe coding. In this episode, Chris speaks with Miklós Koren of Central European University about how AI is reshaping open source and the software industry. They explore the economics of incentives, evolving collaboration patterns, and what th...

What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at Qualcomm’s Edge Impulse, to discuss the current state and future of Edge AI in 2026. We discuss Gen AI, Small Models, and Cascades of Models, along with real-world constraints like latency, power, and privacy. We also dive in...

What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey from criticizing AI to experimenting with it firsthand. We explore Steve’s programming language Rue, largely built with the help of AI tools like Claude, and discuss what this means for software engineering and the future of coding i...

AI is reshaping global power, from chip manufacturing and computing power to AI governance and US-China relations.  In this episode, Ben Buchanan, Assistant Professor at The Johns Hopkins University and former White House Special Advisor for AI, explores how AI policy, geopolitics, and international cooperation intersect with AI  innovation and AI safety. We discuss the strategic importance of computing power, the future ...

As AI accelerates innovation and adoption, leaders are facing rising cognitive load, shifting systems, and new emotional realities inside their organizations. In this episode, Deloitte’s Chief Innovation Officer Deborah Golden joins us to explore how AI is reshaping leadership, why vulnerability and empathy are critical in this moment, and how anti-fragility, not just resilience, will define the future of work.

Featuring:

• D...

AI is moving fast from research to real-world deployment, and when things go wrong, the consequences are no longer hypothetical. In this episode, Sean McGregor, co-founder of the AI Verification & Evaluation Research Institute and also the founder of the AI Incident Database, joins Chris and Dan to discuss AI safety, verification, evaluation, and auditing. They explore why benchmarks often fall short, what red-teaming at DEFCON...

AI agents are moving from demos to real workplaces, but what actually happens when they run a company? In this episode, journalist Evan Ratliff, host of Shell Game, joins Chris to discuss his immersive journalism experiment building a real startup staffed almost entirely by AI agents. They explore how AI agents behave as coworkers, how humans react when interacting with them, and where ethical and workplace boundaries begin to brea...

As AI increasingly shapes geopolitics, elections, and civic life, its impact on democracy is becoming impossible to ignore. In this episode, Daniel and Chris are joined by security expert Bruce Schneier to explore how AI and technology are transforming democracy, governance, and citizenship. Drawing from his book Rewiring Democracy, they explore real examples of AI in elections, legislation, courts, and public AI models, the risks ...

As generative AI moves into production, traditional guardrails and input/output filters can prove too slow, too expensive, and/or too limited. In this episode, Alizishaan Khatri of Wrynx joins Daniel and Chris to explore a fundamentally different approach to AI safety and interpretability. They unpack the limits of today’s black-box defenses, the role of interpretability, and how model-native, runtime signals can enable safer...

In this start-of-year FC episode, Chris and Daniel break down what really mattered in AI in 2025, and what to expect in 2026. They explore the rise of AI agents, the practical reality of multimodal AI, and how reasoning models are reshaping workflows. The conversation dives into infrastructure and energy constraints, the continued value of predictive models, and why orchestration (not just better models) is becoming the defining sk...